Automatic prediction of obstructive sleep apnea in patients with temporomandibular disorder based on multidata and machine learning

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Aug. 21, 2024

Obstructive sleep apnea (OSA) is closely associated with the development and chronicity of temporomandibular disorder (TMD). Given intricate pathophysiology both OSA TMD, comprehensive diagnostic approaches are crucial. This study aimed to develop an automatic prediction model utilizing multimodal data diagnose among TMD patients. We collected a range data, including clinical characteristics, portable polysomnography, X-ray, MRI from 55 patients who reported problems. was then analyzed using advanced machine learning techniques. Three-dimensional VGG16 logistic regression models were used identify significant predictors. Approximately 53% (29 out 55) had OSA. Performance accuracy evaluated regression, multilayer perceptron, area under curve (AUC) scores. in 80.00-91.43%. When added algorithm, AUC score increased 1.00, indicating excellent capability. Only obstructive index statistically predicting patients, threshold 4.25 events/h. The learned features convolutional neural network visualized as heatmap gradient-weighted class activation mapping revealing that it focuses on differential anatomical parameters depending absence or presence In OSA-positive cases, nasopharynx, oropharynx, uvula, larynx, epiglottis, brain region recognized, whereas OSA-negative tongue, nose, nasal turbinate, hyoid bone recognized. Prediction heat map analyses support plausibility usefulness this artificial intelligence-based diagnosis providing deeper understanding regions distinguishing between non-OSA.

Language: Английский

Depression and Related Clinical Factors in Adolescent Patients with Temporomandibular Disorder

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 11, 2024

Temporomandibular disorder (TMD) is a musculoskeletal characterized by functional limitations and pain in the masticatory muscle temporomandibular joint. In adolescent, TMD can significantly impact mental health lead to psychosocial disabilities. This study aims investigate correlation between depression, as assessed Symptom-Checklist-90-Revised (SCL-90-R) clinical factors adolescent patients with TMD. included total of 185 adolescents (69 males, 116 females, mean age 15.15 ± 2.17) Korea, who was diagnosed November 2020 May 2023. Patients were categorized into three groups: 46 young aged 10–13, 78 middle 14–16, 61 older 17–18. Clinical data collected from medical records at patients’ initial visit. Depression evaluated SCL-90-R. exhibited strong age. patients, depression scores associated stressful conditions, sleep problems, dysfunction index, presence tinnitus, craniomandibular history trauma, habitual irregular diet. generalized linear model, most significant association aging, followed clenching habits, obsessive-compulsiveness, somatization. contrast, intensity duration not related patients. Also, osteoarthritis panoramic image The results suggest that clinicians evaluate state concise information, enhancing management treatment this population.

Language: Английский

Distinguishing Between Acute and Chronic Temporomandibular Disorder in Adolescent Patients

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 23, 2024

This study compared the clinical and imaging characteristics of chronic temporomandibular disorder (TMD) to those acute TMD in adolescent patients identify factors contributing symptom chronicity with TMD. The 158 participants were divided into (symptom duration < 6 months) ≥ groups. Clinical reports, panoramic radiographs, magnetic resonance images (MRIs) joint retrospectively reviewed between results showed that overall women-to-men ratio among was 1.87:1 did not differ significantly Moreover, group, group a longer treatment duration; smaller anterior posterior spaces; greater nasomaxillary (Na-Mx) midline discrepancy; more prevalent disc displacement (ADD); higher rates bruxism, poor posture, sleep problems, headache, irregular diet. Treatment 1 year most strongly associated TMD, followed by space narrowing, ADD on MRI, Na-Mx discrepancy, bruxism. Therefore, as progresses, tends increase, are likely experience structural changes. Clinicians should consider these findings diagnosis adolescents

Language: Английский