A systematic review to identify assessment instruments for social isolation or loneliness in adults with heart failure

Deleted Journal, Journal Year: 2025, Volume and Issue: 2(1)

Published: March 7, 2025

Abstract Social isolation and loneliness are frequently associated with heart failure. It is unclear how these constructs assessed in adults living failure which warrants further exploration. This review aimed to identify social a systematic reported according PRISMA registered Prospero on 18 March 2024 [CRD42024518571]. The bibliographic databases, MEDLINE, CINAHL, Scopus were searched from inception 20 2024. Original quantitative studies assessing and/or of using patient-reported instrument written English language included. Joanna Briggs Institute Critical Appraisal checklists used assess the quality included studies. results presented narratively. Thirty (17 cohort studies, 9 cross-sectional 2 RCTs, case control) 529,665 participants (mean age ranged 52 83 years, 57% women) University California Los Angeles Loneliness Scale was most commonly while composite measures network size frequency contacts exert deleterious effects both mental physical health, significantly diminishing life satisfaction. improved use assessment instruments may contribute more effective interventions, ultimately enabling care that enhance health outcomes

Language: Английский

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Depressive symptoms partially mediate the relationship between psychosocial factors and epigenetic age acceleration in a multi-racial/ethnic sample of older adults

Brain Behavior & Immunity - Health, Journal Year: 2025, Volume and Issue: 45, P. 100994 - 100994

Published: April 13, 2025

Psychosocial factors, including cumulative psychosocial stress and loneliness, have been linked to epigenetic aging in older adults. Further, depressive symptoms established relationships with both factors aging. However, it is not known whether mediate the association between aging.We conducted linear regression models examine associations stress, five age acceleration (AA) measures estimated by DNA methylation a multi-racial/ethnic sample of 2681 adults from Health Retirement Study (mean age: 70.4 years). For all identified associations, we tested for effect modification sex educational attainment performed mediation analysis characterize role on these associations.Psychosocial were each associated at least one measure AA (FDR q < 0.05). observed interactions DunedinPACE, as well loneliness GrimAA, PhenoAA, females individuals without college degree appearing more sensitive effects Depressive mediated 24 % 35 HannumAA, 40 37 GrimAA respectively. this study may help elucidate relationship aging, which critical understanding biological mechanisms through contribute age-related disease.

Language: Английский

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The Ambivalent Impact of Digital Technology on Loneliness: Navigating Connection and Isolation in the Digital Age

Sinergi International Journal of Psychology, Journal Year: 2025, Volume and Issue: 2(3), P. 181 - 197

Published: April 18, 2025

Loneliness and social isolation have gained increasing attention as significant public health concerns, exacerbated by the COVID-19 pandemic. This study explores psychological, social, demographic dimensions of loneliness, emphasizing its impact on mental well-being. A systematic literature review was conducted using multiple academic databases, including PubMed, Scopus, Web Science. The findings confirm that loneliness is strongly associated with depression, anxiety, psychological distress, young women older adults being particularly vulnerable. Digital technology has played a dual role, offering both support and, in some cases, reinforcing disconnection. Regional disparities highlight economic insecurity limited healthcare access further exacerbate developing nations. discussion emphasizes importance targeted policy interventions, community-based programs, integration into primary healthcare, awareness campaigns. Technology should be used strategically to enhance connectivity rather than replace face-to-face interactions. identifies key research gaps, such need for longitudinal studies assess long-term intervention effectiveness. Future explore intersection socioeconomic determinants develop holistic, evidence-based strategies mitigating effects. Addressing requires multifaceted, collaborative approach integrating economic, technological solutions overall

Language: Английский

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Sex differences in the impact of marital status on coronary artery disease outcomes in Korea

Coronary Artery Disease, Journal Year: 2025, Volume and Issue: unknown

Published: April 17, 2025

Background Coronary artery disease (CAD) outcomes are influenced by social determinants, including marital status. However, research on the sex-specific effects of status CAD is limited. This study aimed to evaluate relationship between and clinical patients with stratified according sex in Korea. Methods A total 3476 who underwent percutaneous coronary intervention (PCI) were enrolled this retrospective observational study. Patients categorized into married nonmarried groups based demographic data at time admission. The primary endpoint was all-cause mortality. Results Among population, 20.7% women 11.5% men PCI for nonmarried. For 87.1% women, cause being death a spouse, whereas 48.3% unmarried men, most common unmarried. During median follow-up 53.3 months, analysis using Cox proportional hazard regression model, associated higher [adjusted ratio (HR): 2.24, 95% confidence interval (CI): 1.22–4.09, P = 0.009] cardiovascular (adjusted HR: 2.63, CI: 19.91–5.80, 0.017) deaths but not women. Conclusion Marital independently predicted adverse highlighting importance approaches assessment determinants care. Future studies should explore broader economic factors inform targeted interventions.

Language: Английский

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Social Isolation Is Associated With the Acceleration of Death and Incident Cardiovascular Disease in Adults With Chronic Kidney Disease

Journal of the American Heart Association, Journal Year: 2025, Volume and Issue: unknown

Published: May 22, 2025

Background Individuals with chronic kidney disease are at markedly increased risk of incident cardiovascular diseases (CVDs) and premature death. The impact social isolation on adverse outcomes in remained understudied. Methods This prospective cohort study included 13 090 individuals from the UK Biobank. exposure was categorized into 3 levels: least, moderately, most isolated. Using accelerated failure time restricted mean survival analyses. Results Compared being least isolated, moderate associated acceleration all‐cause death a ratio 0.87 (95% CI, 0.82–0.93; P <0.001) 0.76 0.70–0.82; <0.001), respectively, differences 49.1 71.6 days within 10 years. We observed marginal association (time ratio, 0.93 [95% 0.87–0.99]; =0.039) 0.79–0.96]; =0.005) CVD. But significant only for stroke, not coronary artery disease. Based pathways revealed by directed acyclic graph constructed using Bayesian network, we conducted inverse odds ratio–weighted mediation to decompose total effect death, found that CVD sarcopenia mediated 21.8% 7.1–43.0) Conclusions Social is shortened accelerates onset support warrants attention prevention these high‐risk individuals.

Language: Английский

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A bibliometric review and visualization of research on myocardial ischemia/reperfusion injury in patients with diabetes mellitus from 2004 to 2024

Medicine, Journal Year: 2025, Volume and Issue: 104(22), P. e42707 - e42707

Published: May 30, 2025

The incidence of diabetes mellitus (DM) is increasing annually, and hearts patients with DM are more sensitive to myocardial ischemia/reperfusion (MI/R) injury. However, the specific mechanisms remain unknown. Through a bibliometric analysis published research, this study primarily summarizes clarifies current status research on diabetic MI/R Publications related injury in from January 1, 2004, July 31, 2024, were obtained by searching Web Science Core Collection. method was adopted using Excel 2021, CiteSpace, VOSviewer, Pajek R package "Bibliometrix." In total, 634 papers 221 reviews during period that fit criteria. number annual scientific publications citations has steadily increased. majority these studies 1164 institutions 70 countries, China United States ranking first second, respectively, terms publication volume. Among leading field, Air Force Military Medical University, Wuhan University Hong Kong found occupy top positions. Keyword reveals recent hotspots include antidiabetic agents, anesthetics extracellular vesicles. Emerging trends such as ferroptosis, mitophagy, gut microbiota closely future directions. This provided detailed overview key contributors, institutions, highlighting changes progression leads world paper production; however, international cooperation essential for enhancing quality research. our study, we literature visualization will help investigators gain deeper understanding progress into

Language: Английский

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The 6 Pillars of Lifestyle Medicine and Prevalence of Cardiovascular and Cardiometabolic Diseases in Brazil: A Cross-Sectional, Population-Based Study Involving 88,531 Adults

American Journal of Lifestyle Medicine, Journal Year: 2025, Volume and Issue: unknown

Published: June 5, 2025

Objective: We aimed to estimate the prevalence of cardiovascular diseases (CVDs) and cardiometabolic (CMB) in Brazil, their relationship with a healthy lifestyle score based on six pillars medicine proposed by American College Lifestyle Medicine. Methods: Data were derived from 2019 Brazilian National Health Survey, nationwide cross-sectional study. The CVDs/CMB was medical-endorsed, self-reported diagnoses weighted for sample strata. A (0-14 points; higher score, better) incorporates physical activity, diet, sleep, mental health, risky substance use, social connections. Results: Among 88,531 adults included analysis (mean age: 47.1 years; 52.9% female), ranged 1.9% (stroke) 25.9% (hypertension). Weighted Poisson regression models, adjusted age, sex, socioeconomic status, geographic disparities, showed an inverse linear between prevalence. Participants highest quartile exhibited lower heart [0.48 (95% CI: 0.43, 0.53)], stroke [0.35 0.29, 0.43)], hypertension [0.85 0.80, 0.90)], diabetes [0.80 0.70, 0.91)], dyslipidemia [0.73 0.66, 0.80)], obesity [0.81 0.74, 0.88)], compared lowest ( P < 0.001 all). Conclusions: Higher scores are associated major Brazil.

Language: Английский

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Alexithymia and estimated 10-year cardiovascular disease risk in healthy adults: a community-based cross-sectional study

Frontiers in Psychology, Journal Year: 2024, Volume and Issue: 15

Published: Dec. 4, 2024

This cohort study aimed to explore whether and what extent alexithymia would be associated with cardiovascular disease (CVD) risk over an estimated 10-year period, above established clinical cofactors (i.e., depressive symptoms, quality of life, sociodemographic, anthropometric, lifestyle, biological data), in a low-risk population blood donors.

Language: Английский

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The impact of loneliness on healthcare costs and service utilisation and the cost-effectiveness of loneliness interventions: a systematic review

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 16, 2024

Abstract Introduction Loneliness is an unpleasant, subjective experience that can affect people at all stages of life. Given its association with a range physical and mental health problems, it important to assess the costs loneliness healthcare system. The current study aimed to: (i) review literature on social care impacts loneliness, (ii) economic evaluations interventions address loneliness. Methods We conducted systematic studies published from 2008 2023 by searching five bibliographic databases, two sources grey literature, reference lists relevant reviews. Studies estimating cost expenditure, resource utilisation were included impact Return investment, return cost-effectiveness interventions. reported either or outcomes included. No limitations placed inclusion for populations, age groups, language. quality appraisal narrative synthesis results. Results 39 eligible studies: Five estimated expenditure 22 use, 18 Most focused older adult populations. Findings relating cost/expenditure service use inconsistent varied: some excess costs/expenditure associated while others found lower Economic evaluation covered wide different intervention types. They generally indicated be cost-effective, but less likely cost-saving not consistently effective in reducing Discussion Inconsistent varied findings system meant was difficult synthesise Therefore, we cannot derive confident conclusions about related this review. Future research should prioritise care, direct randomised controlled trials long-term follow-ups appropriately these evidence gaps. Research younger populations also considered priority.

Language: Английский

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