A Comprehensive Review on Exploring the Potential of Phytochemicals and Biogenic Nanoparticles for the Treatment of Antimicrobial-Resistant Pathogenic Bacteria
Shibasini Murugan,
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T. Senthilvelan,
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Mani Govindasamy
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et al.
Current Microbiology,
Journal Year:
2025,
Volume and Issue:
82(2)
Published: Jan. 18, 2025
Language: Английский
Pioneering study of Egyptian Neem and Jojoba extracts with molecular docking combat hospital multidrug resistant bacteria
Brazilian Journal of Microbiology,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 8, 2025
Language: Английский
Sustainable synthesis of copper oxide nanoparticles with antibacterial activity using siderophores produced by Pseudomonas sp. ABC1
Walter Cañón Mancisidor,
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Bárbara Rodríguez Escalona,
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Katherine Delgado Vargas
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et al.
Research Square (Research Square),
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 11, 2025
Abstract
Copper
oxide
nanoparticles
(CuO
NPs)
have
significant
applications
in
bioscience
and
biomedicine.
Numerous
physical
chemical
methods
exist
for
synthesizing
CuO
NPs;
however,
the
biogenic
synthesis
of
using
bacterial
metabolites
offers
a
sustainable
approach
to
obtaining
metal
with
specific
shapes
sizes.
In
this
study,
we
produced
NPs
through
production
system
based
on
secondary
Pseudomonas
sp.
ABC1.
We
characterized
generated
various
techniques
evaluated
their
application
as
antibacterial
agents.
The
crystalline
structures
were
confirmed
by
X-ray
diffraction,
which
showed
diffraction
planes
corresponding
pattern.
Energy-dispersive
spectroscopy
composition
NPs.
Scanning
electron
microscopy
images
displayed
spherical
particles
arranged
independently,
an
average
size
19
nm.
exhibited
inhibitory
effect
Escherichia
coli
Staphylococcus
aureus,
resulting
growth
inhibition
after
24
hours
incubation.
Our
results
underscore
potential
siderophores
activity.
Language: Английский
Exploring the Antimicrobial Potential of Azadirachta Indica Against Pseudomonas Aeruginosa a Natural Approach to Combat Drug Resistance
Dilbar Hussain,
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A Hassan,
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Bushra Rehman
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et al.
Indus journal of bioscience research.,
Journal Year:
2025,
Volume and Issue:
3(2), P. 316 - 322
Published: Feb. 25, 2025
Pseudomonas
aeruginosa
is
a
multidrug-resistant
pathogen
known
for
its
ability
to
form
biofilms,
leading
chronic
infections
and
reduced
antibiotic
effectiveness.
Natural
plant
extracts,
such
as
neem
(Azadirachta
indica),
have
shown
promising
antimicrobial
properties.
This
study
evaluates
the
antibacterial
anti-biofilm
activities
of
extracts
against
P.
aeruginosa.
Phytochemical
screening
was
conducted
on
ethanol
methanol
identify
bioactive
compounds.
Antimicrobial
susceptibility
testing
performed
using
agar
well
diffusion
method,
while
minimum
inhibitory
concentration
(MIC)
bactericidal
(MBC)
were
determined.
Biofilm
inhibition
assessed
crystal
violet
assay
at
varying
extract
concentrations
(50,
100,
250,
500
µg/mL).
analysis
confirmed
presence
flavonoids,
phenolic
compounds,
alkaloids,
tannins,
saponins,
terpenoids,
with
showing
higher
concentrations.
Neem
exhibited
dose-dependent
activity,
highest
zone
22
mm
µg/mL
an
MIC
100
µg/mL.
The
MBC
determined
be
250
µg/mL,
confirming
neem’s
biofilm
showed
that
formation
by
20%
50
85%
indicating
strong
anti-adherence
activity.
Statistical
significant
differences
(p
<
0.05)
between
different
concentrations,
doses
demonstrating
stronger
inhibition.
demonstrated
potent
effects
aeruginosa,
results
comparable
some
conventional
antibiotics.
compounds
flavonoids
contributes
efficacy.
Given
increasing
challenge
resistance,
may
serve
potential
natural
agent
or
adjunct
therapy.
Language: Английский
Valorization of noni-leaf tea as a by-product of nanofiltration for the green synthesis of copper oxide nanoparticles with improved antimicrobial properties
Materials Science and Engineering B,
Journal Year:
2025,
Volume and Issue:
317, P. 118172 - 118172
Published: Feb. 28, 2025
Language: Английский
Neutering Pathogens through Green Synthesized Nanoparticles
Microbial Pathogenesis,
Journal Year:
2025,
Volume and Issue:
unknown, P. 107495 - 107495
Published: March 1, 2025
Language: Английский
The Composition of the Dispersion Medium Determines the Antibacterial Properties of Copper (II) Oxide Nanoparticles Against Escherichia coli Bacteria
Nanomaterials,
Journal Year:
2025,
Volume and Issue:
15(6), P. 469 - 469
Published: March 20, 2025
Copper
(II)
oxide
nanoparticles
(CuO
NPs)
attract
much
attention
as
a
promising
antimicrobial
agent.
We
studied
the
antibacterial
properties
of
three
types
CuO
NPs
against
Escherichia
coli
bacteria:
flake-shaped
particles
with
diameter
50–200
nm
and
thickness
10–20
(CuO-CD
synthesized
by
chemical
deposition),
spherical
size
20–90
(CuO-EE
obtained
electrical
explosion),
rod-shaped
length
100–200
30
×
70
(CuO-CS
commercial
sample).
tested
how
shape,
size,
concentration
NPs,
composition
dispersion
medium
affected
NPs.
prepared
dispersions
based
on
distilled
water,
0.9%
NaCl
solution,
LB
broth
Lennox
used
Triton
X-100
sodium
dodecyl
sulfate
(SDS)
stabilizers.
The
was
1–100
mg
L−1.
showed
that
stabilizer
type
had
greatest
influence
effects
observed
maximum
effect
for
all
NP
dispersed
in
water
without
stabilizer,
well
SDS
stabilizer.
inhibition
culture
growth
under
CuO-EE
(by
30%)
1.3–1.8
times
depending
particles).
In
saline
were
minimal;
some
cases,
even
promoted
bacterial
growth.
increased
but
decreased
them
water.
Finally,
among
particle
types,
CuO-CS
turned
out
to
be
most
bactericidal,
which
is
probably
due
their
morphology
small
diameter.
At
same
time,
aggregation
colloidal
systems
we
did
not
have
linear
action
properties.
These
results
can
development
coatings
preparations
achieve
efficiency,
taking
into
account
expected
conditions
use.
Language: Английский
The dual role of bio-inspired palladium nanoparticles in antibacterial action and wound healing: An in vitro and in vivo study
Ashwini Singhal,
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Gyan Prakash Meghwal,
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Apurva Jaiswal
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et al.
Journal of King Saud University - Science,
Journal Year:
2025,
Volume and Issue:
0, P. 1 - 12
Published: April 18, 2025
Language: Английский
Biogenic Copper and Copper Oxide Nanoparticles to Combat Multidrug-Resistant Staphylococcus aureus: Green Synthesis, Mechanisms, Resistance, and Future Perspectives
Biotechnology Reports,
Journal Year:
2025,
Volume and Issue:
unknown, P. e00896 - e00896
Published: May 1, 2025
Language: Английский
Dual-functional copper oxide nanofluids for transformer: Synergistic enhancement of antimicrobial and insulating properties
Haidan Lin,
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Lijie Xu,
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Qunying Yu
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et al.
AIP Advances,
Journal Year:
2025,
Volume and Issue:
15(5)
Published: May 1, 2025
Oil
in
transformer
insulation
systems
critically
safeguards
grids,
yet
microbial
contamination
catastrophically
compromises
dielectric
integrity,
threatening
grid
resilience
worldwide.
To
address
this
dual
challenge
of
biocontamination
and
degradation,
we
engineered
bifunctional
copper
oxide
nanofluids
(CuO
NFs)
through
crystallographic
tailoring
surface
charge
optimization.
Two
dominant
actinomycetes
(Mycoplana
Rothia),
isolated
from
operational
transformers,
achieved
up
to
98.19%
96.32%
inactivation
rates
when
exposed
CuO
NFs,
coupled
with
a
1.62-fold
increase
AC
breakdown
voltage
compared
base
oil,
owing
the
designed
monoclinic-phase
nanoparticles
(+20.14
±
1.5
mV)
that
disrupted
integrity
via
electrostatic
adhesion
reactive
oxygen
species
(ROS)
generation,
which
is
first
demonstration
nanoscale
ROS-mediated
antimicrobial
mechanisms
oil-immersed
systems.
This
work
provides
robust
strategy
for
development
NFs
mitigate
enhance
insulating
properties.
Language: Английский