Lipids in Health and Disease, Journal Year: 2025, Volume and Issue: 24(1)
Published: April 16, 2025
Language: Английский
Lipids in Health and Disease, Journal Year: 2025, Volume and Issue: 24(1)
Published: Jan. 30, 2025
The relationship between body roundness index (BRI), a new obesity index, and frailty has not been established. This study aims to compare the associations of traditional mass (BMI) BRI with risk all-cause mortality. clinical data 15,157 participants over 40 years old from National Health Nutrition Examination Survey (NHANES) 2003 2018 were analyzed. Based on weighted logistic regression, COX regression restricted cubic spline, BMI odds mortality estimated. receiver operating characteristic curve (ROC) concordance used evaluate ability predict survival. Weighted showed that trend increasing increase (P for < 0.0001, respectively). After adjusting all confounding factors, association was stronger (OR: 1.20, 95% CI: 1.13–1.27, P 0.0001), slightly weaker 1.14, 1.08–1.21, 0.0001). ROC area under (AUC) predicting 0.628, while AUC 0.603, difference two significant (PDeLong 0.001). In addition, in survival analysis, U-shaped Piecewise based inflection point shows when 7.33, an reduces (HR: 0.85, 0.78–0.92, ≥ increases 1.19, 1.03–1.38, = 0.02); 33.57, 0.84, 0.78–0.91, 1.18, 1.04–1.34, 0.01). Moreover, time-dependent c-index frail people comparable BMI. American population old, both are independently positively associated frailty. than have individuals, abilities
Language: Английский
Citations
1
Journal of Health Population and Nutrition, Journal Year: 2025, Volume and Issue: 44(1)
Published: Jan. 2, 2025
Gallstone disease (GSD) is a common and costly health issue with multifactorial etiology linked to obesity. The Weight-Adjusted-Waist Index (WWI) novel anthropometric measure that incorporates both weight waist circumference, potentially offering better assessment of GSD risk associated adiposity. This study aims evaluate the association between WWI prevalence GSD. We conducted cross-sectional involving 19,426 participants divided into stone (n = 4,398) non-stone 15,028) groups based on ultrasound-confirmed was calculated, its analyzed using logistic regression models, adjusting for confounders such as age, gender, comorbid conditions. 22.6%. Participants had higher mean greater proportion females, Body Mass (BMI) compared those without significantly in group (p < 0.001). fatty liver also Laboratory findings indicated subclinical inflammatory state highest tertile an increased odds ratio (OR 1.23, 95% CI: 1.13–1.35 fully adjusted model). demonstrates superior predictive ability gallstones other obesity markers obese populations. positively GSD, independent traditional factors. These suggest could serve practical screening tool identify individuals at emphasizing need targeted interventions address central
Language: Английский
Citations
0
Frontiers in Cardiovascular Medicine, Journal Year: 2025, Volume and Issue: 11
Published: Jan. 10, 2025
The weight adjusted waist index (WWI) represents a novel indicator for assessing central obesity. objective of this study is to investigate the association between WWI and coronary heart disease (CHD). data 44,528 participants in total were gathered from NHANES database 1999 2020. calculated as circumference (WC, cm) divided by square root body (kg), CHD was determined based on participants' self-reports. examined using multiple logistic regression analysis, restrictive cubic spline (RCS), receiver operating characteristic (ROC) curve, mediation subgroup interaction analyses. This cross-sectional investigation. A included [50.23% male; mean 10.89 (0.01) cm/√kg]. multivariate analysis revealed that three models, one-standard-deviation increment associated with an increased probability occurrence 2.39 (2.22,2.57),1.47 (1.32,1.65), 1.15 (1.00,1.32) times, respectively. Additionally, RCS indicated linear relationship CHD. ROC results showed discriminatory power superior mass (BMI) WC. Glycated hemoglobin (HbA1c) partially mediated Subgroup analyses confirmed age, systolic blood pressure, diabetes status had significant impact (P <0.05). level has been demonstrated be risk Specifically, increases, becomes higher. On basis, it hypothesized may potentially serve independent factor CAD, thereby highlighting substantial value identification management
Language: Английский
Citations
0
Lipids in Health and Disease, Journal Year: 2025, Volume and Issue: 24(1)
Published: Jan. 25, 2025
Abstract Background Stroke has emerged as an escalating public health challenge among middle-aged and older individuals in China, closely linked to glycolipid metabolic abnormalities. The Hemoglobin A1c/High-Density Lipoprotein Cholesterol (HbA1c/HDL-C) ratio, integrated marker of homeostasis, may serve a novel predictor stroke risk. Methods Our investigation utilized data from the China Health Retirement Longitudinal Study cohort (2011–2018). cases were identified based on self-reported, physician-confirmed diagnoses. Logistic regression models established determine correlation between HbA1c/HDL-C prevalence (2011) well cumulative mean (2011–2015) new incidence (2015–2018). Additionally, smoothed curve fitting, subgroup analyses, interaction tests conducted ensure robustness findings. Results In cross-sectional analysis, 8,502 participants enrolled, whom 189 had history stroke. findings revealed significant positive linear relationship after adjusting for covariates (OR: 1.26, 95% CI: 1.09–1.45). When was categorized into tertiles, only highest tertile (T3) showed with compared lowest (T1) (OR:1.71, 1.05–2.77). longitudinal analysis 5,165 participants, 336 new-onset over follow-up period 7 years. Adjusting confounders, higher exhibited increased likelihood 1.14, 1.01–1.29). Using T1 reference, fully adjusted OR 1.65 (95% 1.21–2.24) T2 1.54 1.08–2.19) T3. predictive value risk assessment have been significantly improved traditional HDL-C HbA1c. Consistent associations observed across most stratified subgroups. Conclusions Elevated baseline levels are associated underscoring potential clinical long-term prevention strategies.
Language: Английский
Citations
0
Frontiers in Public Health, Journal Year: 2025, Volume and Issue: 13
Published: Feb. 12, 2025
Background This study explores the longitudinal relationship between Weight-Adjusted Waist Index (WWI), an innovative obesity metric, and stroke incidence in aged 45 older Chinese adults. Methods Data from 9,725 individuals years were analyzed China Health Retirement Longitudinal Study (2011–2020). Baseline characteristics across different quartiles of WWI. Stroke incidents determined through self-reported doctor diagnoses. Multivariate logistic regression analyses curve fitting assessed WWI-stroke risk relationship, adjusting for various demographic, lifestyle, health-related factors. Results Higher WWI associated with age higher prevalence adverse health conditions. In fully adjusted model, participants highest quartile had odds ratio 1.52 (95% CI: 1.19, 1.92) compared to lowest quartile. Curve revealed a linear risk, consistent demographic clinical subgroups. Conclusion is linked increased adults over eight-year period. may serve as effective tool predicting long-term within this population. However, limited by reliance on diagnoses presence potential residual confounding
Language: Английский
Citations
0
Lipids in Health and Disease, Journal Year: 2025, Volume and Issue: 24(1)
Published: April 16, 2025
Language: Английский
Citations
0