Overview of Nrf2 as a target in ovary and ovarian dysfunctions focusing on its antioxidant properties DOI Creative Commons

Taha Ghantabpour,

Nasim Goudarzi,

Houman Parsaie

et al.

Journal of Ovarian Research, Journal Year: 2025, Volume and Issue: 18(1)

Published: March 22, 2025

Female infertility is a common issue caused by various factors, such as hormonal imbalances, age-related decline in oocyte quality, and lifestyle choices. Ovarian dysfunction prevalent cause, impacting fertility damaging cells impairing functions. Oxidative stress (OS) condition resulting from an imbalance between natural antioxidants the generation of oxidants. This phenomenon acts double-edged sword, playing crucial role signaling mechanism both physiological pathological processes related to female reproductive system. OS linked ovarian dysfunction, leading cell damage reduced fertility. Nrf2 key regulator oxidative homeostasis, helping defend against improve function women age. Therefore, this review aims highlight system, focusing on its antioxidant properties.

Language: Английский

Ultrasound-assisted extraction combined with enzyme hydrolysis enhanced the anti-aging effects and bioactivity of longan flower, mulberry, and roselle: Phytochemical profiling and in vivo C. elegans validation DOI

Kuo‐Ching Jan,

Mohsen Gavahian

Food Bioscience, Journal Year: 2025, Volume and Issue: unknown, P. 106686 - 106686

Published: April 1, 2025

Language: Английский

Citations

1
Overview of Nrf2 as a target in ovary and ovarian dysfunctions focusing on its antioxidant properties DOI Creative Commons

Taha Ghantabpour,

Nasim Goudarzi,

Houman Parsaie

et al.

Journal of Ovarian Research, Journal Year: 2025, Volume and Issue: 18(1)

Published: March 22, 2025

Female infertility is a common issue caused by various factors, such as hormonal imbalances, age-related decline in oocyte quality, and lifestyle choices. Ovarian dysfunction prevalent cause, impacting fertility damaging cells impairing functions. Oxidative stress (OS) condition resulting from an imbalance between natural antioxidants the generation of oxidants. This phenomenon acts double-edged sword, playing crucial role signaling mechanism both physiological pathological processes related to female reproductive system. OS linked ovarian dysfunction, leading cell damage reduced fertility. Nrf2 key regulator oxidative homeostasis, helping defend against improve function women age. Therefore, this review aims highlight system, focusing on its antioxidant properties.

Language: Английский

Citations

0