Morphometric Blastocyst Assessment: A Retrospective Study Examining the Relationship Between Blastocyst Diameter and Area and Pregnancy Outcomes in Assisted Reproduction Technology Cycles DOI Open Access
Romualdo Sciorio, Pierfrancesco Greco, Luca Tramontano

et al.

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(8), P. 2827 - 2827

Published: April 19, 2025

Objective: In assisted reproductive technology (ART), achieving a successful pregnancy requires optimizing an embryo culture and selecting the single with highest implantation potential, capable of resulting in healthy pregnancy. The primary goal this study was to determine correlation between blastocyst area diameter outcomes ART treatments. Methods: study, were measured whether these morphometric features could predict couples undergoing ICSI. This is retrospective trial analyzing 665 patients who underwent cycle transfer on day 5. Results: Both assessed significantly associated ongoing outcomes. Our results showed that rate (IR) clinical (CPR) higher ≥ 25,000 µm2 compared <25,000 (IR: 69.8% versus 47.9%, p < 0.001; CPR: 65.5% 45.9% 0.001). Additionally, 170 µm resulted IR CPR embryos 68.8% 36.6%, 66.3 35.7%, Conclusions: Blastocyst variables, being objective measurable, are not subject intra-operator variability may serve as promising predictors viability success. These assessments assist embryologists potential from cohort, well identifying those reduced chance generating

Language: Английский

Non-Male Factor Only—ICSI Can Overcome Oocyte Factor in PCOS Patients DOI Open Access

Yasmin Shibli Abu Raya,

Nardin Aslih, Yuval Atzmon

et al.

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(1), P. 244 - 244

Published: Jan. 3, 2025

Background: In this research, we retrospectively studied the influence of IVF vs. ICSI technique on embryo morphokinetics by means a time-lapse incubator in fresh cycles. Methods: A total 2645 treatment cycles resulting ovum pick-up 11,471 fertilized oocytes were included research from 2018 to 2022. The embryos grouped according or ICSI. Embryonic development was monitored using incubator, and they transferred day 3 5. Results: group developed faster had less fragmentation. However, fewer 2PNs achieved more discarded compared IVF. When sibling treated with either analyzed, found that resulted quicker higher KIDScores. Discussion: anovulation PCOS subgroups primary contributors high KIDScores oocytes, indicating might have beneficial effects oocyte factors, similar positive results it provides when male factors are involved. Conclusions: Women undergoing better used spontaneous This study reveals is superior female factor infertility.

Language: Английский

Citations

0
Merging synthetic and real embryo data for advanced AI predictions DOI Creative Commons
Oriana Presacan, Alexandru Dorobanțiu, Vajira Thambawita

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: March 21, 2025

Accurate embryo morphology assessment is essential in assisted reproductive technology for selecting the most viable embryo. Artificial intelligence has potential to enhance this process. However, limited availability of data presents challenges training deep learning models. To address this, we trained two generative models using datasets—one created and made publicly available, one existing public dataset—to generate synthetic images at various cell stages, including 2-cell, 4-cell, 8-cell, morula, blastocyst. These were combined with real train classification stage prediction. Our results demonstrate that incorporating alongside improved performance, model achieving 97% accuracy compared 94.5% when solely on data. This trend remained consistent tested an external Blastocyst dataset from a different clinic. Notably, even exclusively data, achieved high 92%. Furthermore, combining both yielded better than single model. Four embryologists evaluated fidelity through Turing test, during which they annotated inaccuracies offered feedback. The analysis showed diffusion outperformed adversarial network, deceiving 66.6% versus 25.3% lower Fréchet inception distance scores.

Language: Английский

Citations

0
Human embryo stage classification using an enhanced R(2 + 1)D model and dynamic programming with optimized datasets DOI

Abbas Barhoun,

Mohammad Ali Balafar, Amin Golzari Oskouei

et al.

Biomedical Signal Processing and Control, Journal Year: 2025, Volume and Issue: 107, P. 107841 - 107841

Published: March 28, 2025

Language: Английский

Citations

0
Morphometric Blastocyst Assessment: A Retrospective Study Examining the Relationship Between Blastocyst Diameter and Area and Pregnancy Outcomes in Assisted Reproduction Technology Cycles DOI Open Access
Romualdo Sciorio, Pierfrancesco Greco, Luca Tramontano

et al.

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(8), P. 2827 - 2827

Published: April 19, 2025

Objective: In assisted reproductive technology (ART), achieving a successful pregnancy requires optimizing an embryo culture and selecting the single with highest implantation potential, capable of resulting in healthy pregnancy. The primary goal this study was to determine correlation between blastocyst area diameter outcomes ART treatments. Methods: study, were measured whether these morphometric features could predict couples undergoing ICSI. This is retrospective trial analyzing 665 patients who underwent cycle transfer on day 5. Results: Both assessed significantly associated ongoing outcomes. Our results showed that rate (IR) clinical (CPR) higher ≥ 25,000 µm2 compared <25,000 (IR: 69.8% versus 47.9%, p < 0.001; CPR: 65.5% 45.9% 0.001). Additionally, 170 µm resulted IR CPR embryos 68.8% 36.6%, 66.3 35.7%, Conclusions: Blastocyst variables, being objective measurable, are not subject intra-operator variability may serve as promising predictors viability success. These assessments assist embryologists potential from cohort, well identifying those reduced chance generating

Language: Английский

Citations

0