Trends in Prevalence of Rome IV Disorders of Gut‐Brain Interaction During the COVID‐19 Pandemic: Results From a Nationally Representative Sample of Over 160,000 People in the US DOI Open Access
Christopher V. Almario, So Yung Choi, William D. Chey

et al.

Neurogastroenterology & Motility, Journal Year: 2025, Volume and Issue: unknown

Published: March 10, 2025

We hypothesized that disorders of gut-brain interaction (DGBI) increased during the pandemic due to enteropathic nature SARS-CoV-2, together with potential for COVID-19 pandemic-related stress negatively impact axis. To test our hypothesis, we conducted a series pre-specified cross-sectional surveys initiated at beginning trend prevalence Rome IV DGBI over time among nationally representative sample more than 160,000 people in US. From May 2020 2022, performed online adults ≥ 18 years old administered gastroduodenal and bowel questionnaires (e.g., chronic idiopathic constipation [CIC], functional bloating, dyspepsia, irritable syndrome [IBS]) along sociodemographic comorbidity questions. Multivariable logistic regression was used adjust confounders. Overall, 160,154 completed surveys. During pandemic, IBS (6.1% [May 2020] 11.0% 2022]; +0.188%/month; adjusted p < 0.001) CIC (6.0% 6.4% +0.056%/month; time. Among those IBS, largest increase seen mixed (+0.085%/month), followed by (+0.041%/month) diarrhea (+0.037%/month). No changes were other examined DGBI. observed significant increases CIC. Further research exploring pathophysiologic mechanisms underlying these findings whether trends persist beyond is warranted.

Language: Английский

Trends in Prevalence of Rome IV Disorders of Gut‐Brain Interaction During the COVID‐19 Pandemic: Results From a Nationally Representative Sample of Over 160,000 People in the US DOI Open Access
Christopher V. Almario, So Yung Choi, William D. Chey

et al.

Neurogastroenterology & Motility, Journal Year: 2025, Volume and Issue: unknown

Published: March 10, 2025

We hypothesized that disorders of gut-brain interaction (DGBI) increased during the pandemic due to enteropathic nature SARS-CoV-2, together with potential for COVID-19 pandemic-related stress negatively impact axis. To test our hypothesis, we conducted a series pre-specified cross-sectional surveys initiated at beginning trend prevalence Rome IV DGBI over time among nationally representative sample more than 160,000 people in US. From May 2020 2022, performed online adults ≥ 18 years old administered gastroduodenal and bowel questionnaires (e.g., chronic idiopathic constipation [CIC], functional bloating, dyspepsia, irritable syndrome [IBS]) along sociodemographic comorbidity questions. Multivariable logistic regression was used adjust confounders. Overall, 160,154 completed surveys. During pandemic, IBS (6.1% [May 2020] 11.0% 2022]; +0.188%/month; adjusted p < 0.001) CIC (6.0% 6.4% +0.056%/month; time. Among those IBS, largest increase seen mixed (+0.085%/month), followed by (+0.041%/month) diarrhea (+0.037%/month). No changes were other examined DGBI. observed significant increases CIC. Further research exploring pathophysiologic mechanisms underlying these findings whether trends persist beyond is warranted.

Language: Английский

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