
Vaccine, Journal Year: 2025, Volume and Issue: 59, P. 127296 - 127296
Published: May 24, 2025
Vaccine hesitancy (VH) poses a major challenge to achieving high COVID-19 vaccination rates. Universities, with mandatory primary dose policies but optional boosters, offer unique setting study VH dynamics. This aimed estimate prevalence and identify key factors influencing across booster doses among university students. In this cross-sectional study, all actively enrolled students at the University of Waterloo, Ontario, Canada, during Winter 2024 were invited complete an online survey. Means standard deviations calculated for scores proportions binary VH. Differences compared using paired t-tests chi-square. Generalized Estimating Equations was applied model changes in from boosters predictors Interaction terms tested evaluate dose-specific effects on Among 4453 respondents, increased 17 % 33.4 higher (Mean ± SD: 10.9 8.1) than 7.3 7.1). Women (aOR = 1.06, 95 CI 1.01-1.11) younger 1.62, 1.25-2.10) showed largest increases, especially boosters. Students low perceived risk, negative perceptions boosters' safety effectiveness, intention follow government recommendations, no prior flu or meningococcal exhibited greatest increases when shifting doses. Conversely, religious affiliation those whose decisions unaffected by mandates smaller The rise appears driven demographic, psychological, behavioral factors. Tailored interventions that promote clear communication, improve access, strengthen confidence recommendations rather reliance are critical reducing sustaining vaccine uptake population.
Language: Английский