Nature Synthesis, Journal Year: 2024, Volume and Issue: unknown
Published: Sept. 10, 2024
Language: Английский
Nature Communications, Journal Year: 2025, Volume and Issue: 16(1)
Published: Jan. 3, 2025
Language: Английский
Citations
0
Trends in Chemistry, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
Language: Английский
Citations
0
Trends in Chemistry, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 1, 2025
Language: Английский
Citations
0
Organic Letters, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 20, 2025
A radical fluorosulfonylation of allyl bromides was achieved under electroreductive conditions. This catalyst-free protocol employs mild conditions and enables straightforward access to a new structurally diverse variety previously inaccessible sulfonyl fluorides. We have also illustrated the synthetic value this method by performing scaled-up reactions product derivatization.
Language: Английский
Citations
0
Organic Letters, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 28, 2025
Herein, we describe the successful development of an azido-fluorosulfonylation reaction alkenes under photoredox catalysis, which could allow installation two "clickable" groups, -N3 and -SO2F, on a C-C double bond, with TMSN3 as azide source. The utilization difunctionalization products is also demonstrated in construction library 1,2,3-triazolesulfonyl fluoride compounds well drug molecule ligation by merging copper-catalyzed azide-alkyne cycloaddition (CuAAC) sulfur(VI) exchange (SuFEx), generations click reactions. Mechanistic studies suggest radical fluorosulfonylation/azidation mechanism unveil FSO2N3 new potential fluorosulfonyl precursor.
Language: Английский
Citations
0
Macromolecules, Journal Year: 2025, Volume and Issue: unknown
Published: March 24, 2025
Abiotic sequence-defined polymers hold tremendous promise for applications in nanotechnology, materials science, biomedicine, and data storage. Yet, their synthesis often demands complex, iterative procedures involving multiple deprotection or activation steps. To address this challenge, we present a highly efficient "AB + AC" orthogonal coupling strategy that integrates copper-catalyzed azide–alkyne cycloaddition (CuAAC) iridium-catalyzed AAC (IrAAC). This approach leverages the exceptional chemoselectivity of each reaction to construct oligotriazoles without need protecting groups. Notably, by employing distinct terminal alkyne thioalkyne substrates, our method enables precise, stepwise elongation macromolecular chains on gram scale, even when incorporating diverse functional monomers, underscoring its practicality large-scale applications. Comprehensive analyses via size exclusion chromatography, mass spectrometry, nuclear magnetic resonance techniques confirm high purity structural accuracy resulting oligomers. Moreover, clear fragmentation patterns observed tandem spectrometry (MS/MS) highlight suitability these triazole-rich architectures high-fidelity encoding, thereby paving way advanced high-density information Overall, work not only expands synthetic toolbox creating precision but also offers robust platform development next-generation with tunable properties broad technological relevance.
Language: Английский
Citations
0
ChemistryEurope, Journal Year: 2025, Volume and Issue: unknown
Published: March 27, 2025
Mechanochemical S(VI) exchange reactions are developed on chiral S(VI)–F and S(VI)–Cl centers that fast, solvent–free, high–yielding, enantiospecific. This approach is used to synthesize a range of sulfonimidate esters sulfonimidamides from sulfonimidoyl fluorides chlorides under mild reaction conditions. The broad scope this method demonstrated by its successful reactivity with phenols both primary secondary anilines. Furthermore, substitution in 4–nitrophenol‐derived species substituted (SuPhenEx) successfully achieved. faster, greener, reduces the need for formation fluorinated species, while retaining many advantages SuFEx related reactions.
Language: Английский
Citations
0
Progress in Polymer Science, Journal Year: 2025, Volume and Issue: unknown, P. 101957 - 101957
Published: April 1, 2025
Language: Английский
Citations
0
Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)
Published: April 20, 2024
Abstract The synthesis of sequence-regulated oligosulfates has not yet been established due to the difficulties in precise reactivity control. In this work, we report an example a multi-directional divergent iterative method furnish based on chain homologation approach, which fluorosulfate unit is regenerated. oligosulfate sequences are determined by high resolution mass spectrometry hydrolyzed fragments, and polysulfate periodic copolymers synthesized using oligomeric bisfluorosulfates bi-directional fashion. synthetic utility ligation demonstrated preparing crosslinked network polymers as adhesive materials.
Language: Английский
Citations
3
Chem, Journal Year: 2024, Volume and Issue: 10(6), P. 1644 - 1654
Published: May 9, 2024
Language: Английский
Citations
3