Nanopipettes as a Potential Diagnostic Tool for Selective Nanopore Detection of Biomolecules DOI Creative Commons

Regina Kuanaeva,

Alexander N. Vaneev,

Petr V. Gorelkin

et al.

Biosensors, Journal Year: 2024, Volume and Issue: 14(12), P. 627 - 627

Published: Dec. 19, 2024

Nanopipettes, as a class of solid-state nanopores, have evolved into universal tools in biomedicine for the detection biomarkers and different biological analytes. Nanopipette-based methods combine high sensitivity, selectivity, single-molecule resolution, multifunctionality. The features significantly expanded interest their applications biomolecular detection, imaging, molecular diagnostics real samples. Moreover, ease manufacturing nanopipettes, coupled with compatibility fluorescence electrochemical methods, makes them ideal portable point-of-care diagnostic devices. This review summarized latest progress nanopipette-based nanopore technology biomarkers, DNA, RNA, proteins, peptides, particular β-amyloid or α-synuclein, emphasizing impact on diagnostics. By addressing key challenges expanding diverse areas, nanopipettes are poised to play transformative role future personalized medicine.

Language: Английский

Harvesting sustainable osmotic energy: the art of nanofluidic hydrogel membranes DOI
Brij Mohan, Kamal Singh,

Elnur Ahmadov

et al.

Journal of Energy Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский

Citations

2

Two-Dimensional Material-Based Nanofluidic Devices and Their Applications DOI

Yangjun Cui,

Long Gao, Cuifeng Ying

et al.

ACS Nano, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 9, 2025

Nanofluidics is an interdisciplinary field of study that bridges hydrodynamics, statistical physics, chemistry, materials science, biology, and other fields to investigate the transport fluids ions on nanometric scale. The progress in this field, however, has been constrained by challenges fabricating nanofluidic devices suitable for systematic investigations. Recent advances two-dimensional (2D) have revolutionized development nanofluids. Their ultrathin structure photothermoelectric response make it possible achieve scale control, friction limitation, regulatory response, all which are challenging with traditional solid materials. In review, we provide a comprehensive overview preparation methods corresponding structures three types 2D material-based devices, including nanopores, nanochannels, membranes. We highlight their applications recent exploring physical mechanisms, detecting biomolecules (DNA, protein), developing iontronics improving ion/gas selectivity, generating osmotic energy. discuss facing prospects future advancements field.

Language: Английский

Citations

1

Nanofluids for heat transfer enhancement: a holistic analysis of research advances, technological progress and regulations for health and safety DOI Creative Commons
Emmanuel O. Atofarati, Mohsen Sharifpur, Zhongjie Huan

et al.

Cogent Engineering, Journal Year: 2024, Volume and Issue: 11(1)

Published: Dec. 7, 2024

Nanofluids have emerged as a transformative cooling solutions that offer substantial improvements in various engineering applications require enhanced heat transfer. This review comprehensively analyses the latest research advances, technological progress, and regulatory considerations associated with nanofluids. Beginning an overview of nanofluid properties, composition, preparation methods, we highlight their roles enhancing Detailed examinations experimental studies numerical simulations revealed effectiveness such automobile radiators, electronic cooling, turbine blade solar PV-thermal systems. Health safety were addressed by discussing nanoparticle toxicity, biocompatibility, environmental impacts, along occupational health hazards recommended measures. We scrutinized landscape identified challenges gaps frameworks across Africa, Asia, North America, European Union. A bibliographic analysis progress for transfer provides insights into trends, publication dynamics, key contributors. concludes future prospects potential nanofluids, emphasizing need innovation oversight. underscores scientific advancements while stressing importance protocols robust sustainable technologies.

Language: Английский

Citations

6

Density fluctuations, solvation thermodynamics, and coexistence curves in grand canonical molecular dynamics simulations DOI Creative Commons
Mauricio Sevilla, Luis A. Baptista, Kurt Kremer

et al.

The Journal of Chemical Physics, Journal Year: 2025, Volume and Issue: 162(8)

Published: Feb. 24, 2025

Fluid transport across nanometric channels induced by electric, pressure, and concentration gradients is ubiquitous in biological systems fosters various applications. In this context, computer simulation setups with well-defined open-boundary equilibrium starting states are essential understanding assisting experimental studies. However, computational methods scarce do not typically satisfy all the conditions imposed reality. Namely, absence of external gradients, (1) system interest (SoI) must be at thermodynamic chemical an infinite reservoir particles; (2) fluctuations SoI should sample grand canonical ensemble; (3) local solvation thermodynamics, which extremely sensitive to finite-size effects due solvent depletion, correctly described. This point particularly relevant for out-of-equilibrium systems; (4) finally, method robust enough deal phase transitions coexistence SoI. study, we demonstrate prototypical liquid embedded into a ideal gas particles that adaptive resolution (AdResS) method, coupled particle insertion/deletion steps (AdResS+PI), satisfies these requirements. Therefore, AdResS+PI setup suitable performing stationary non-equilibrium simulations open systems.

Language: Английский

Citations

0

Fluid Flow Measurements in Nanoslits Using Holographic Microscopy DOI Creative Commons
Siyang Yu, Jeremy Orosco, James Friend

et al.

Langmuir, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 26, 2025

To understand the mechanisms driving fluid flow behavior in nanofluidics so that they may be used for on-chip biomedical and chemical applications, fluid's motion itself needs to observable measurable, a difficult challenge at these small scales. We present new method measuring both slow fast flows using high-speed digital holographic microscopy. measure evaporation-driven 25 7 nm tall nanoslit channels, showing consequent speed is about 15 times slower than open atmospheric evaporation due confinement of channel. also measured surface acoustic wave-driven channel, 0.12 m/s from wave propagation 39.7 MHz interacting with A process eliminate many sources noise produce results provided, that─in particular─spatial averaging useful determine dewetting channel over time.

Language: Английский

Citations

0

Thermal Diffusion Mediated Nucleation of Vapor Bubbles on Metal Microspheres DOI
Chenliang Xia,

Zhibin Hu,

Fulong Wang

et al.

International Journal of Mechanical Sciences, Journal Year: 2025, Volume and Issue: unknown, P. 110099 - 110099

Published: Feb. 1, 2025

Language: Английский

Citations

0

Scalable, Light Rechargeable Energy Storage Based on Osmotic Effects and Photochemical Reactions in a Hair‐Thin Filament DOI Open Access
Puguang Peng, Qian Han, Feiyao Yang

et al.

Advanced Energy Materials, Journal Year: 2025, Volume and Issue: unknown

Published: March 6, 2025

Abstract Scalable high‐performance distributed energy management systems (DERMS) on one micron‐scale fiber pose significant challenges. Here, an ultrafine single filamentary iontronic power source (10 µm thickness) is presented that utilizes ion transport within graphene oxide (GO) nanoconfined channels and silver halide interfacial redox reactions to achieve impressive gravimetric (884.95 W kg⁻¹) densities (108.7 Wh kg⁻¹), alongside rapid photo‐recharging capabilities seconds. The controlled ultrasonic spraying technique enables the seamless integration of stable GO filaments, preserving integrity other active layers. Through a detailed investigation dynamics, electrochemical pathway proposed, demonstrating polarization resistance filament battery over certain length, facilitating scalability. These devices exhibit consistent performance across wide temperature range under various environmental conditions, maintaining stability after 10 000 bending cycles. world's thinnest rechargeable battery, with total diameter ≈120 reported, offering promising solution for next‐generation smart textiles, microelectronic circuits, wearable DERMS.

Language: Английский

Citations

0

Fiber-assisted nanoparticle tracking analysis meets nanorheology: a novel approach for probing viscoelastic properties at the nanoscale DOI Creative Commons
Torsten Wieduwilt, Hannah C. Geisler, Ronny Förster

et al.

Nanophotonics, Journal Year: 2025, Volume and Issue: unknown

Published: March 24, 2025

Abstract This study introduces fiber-assisted nanoparticle tracking analysis (FaNTA) as a platform for nanorheology that utilizes an advanced antiresonant optical fiber to analyze the viscoelastic properties of fluids at nanoscale. The confines colloidal nanotracers within fiber-integrated microchannel, significantly extending observation times and improving statistical accuracy. FaNTA system consists custom-designed microstructured fiber, dedicated setup, sophisticated data processing including image filtering, enabling precise determination hydrodynamic diameter thus local viscosity. demonstrates capabilities concept in context rheology by measuring viscosity glycerol-water solutions different concentrations using 50 nm gold nanospheres nanoprobes. By analyzing their individual diffusive motion, accurately determines fluid viscosities with results closely match literature values, validating efficacy nanorheological applications. FaNTA’s high accuracy performance nano- microrheological measurements highlight its broad potential nanoscale materials science, dynamic process studies, life environmental sciences, nanochemistry. innovative approach provides valuable extension current methods offers characterization wide range

Language: Английский

Citations

0

Resistance-Restorable Nanofluidic Memristor and Neuromorphic Chip DOI
Ke Liu, Yong Wang, Miao Sun

et al.

Nano Letters, Journal Year: 2025, Volume and Issue: unknown

Published: April 12, 2025

Resistance drift due to residual ions limits the accuracy of memristor-based neuromorphic computing. Here, we demonstrate nanofluidic memristors based on voltage-driven ion filling within Ångström channels, immersed in asymmetrically concentrated electrolyte solutions. Inspired by brain's waste clearance, restore conductance after 20,000 cycles removing trapped ions, paving way for endurance enhancement. The devices exhibit hour-long retention and ultralow energy consumption (∼0.2 fJ per spike channel). By tuning voltage, frequency, pH, emulate short-term synaptic plasticity. Finally, demonstrated first 4 × memristor array capable recognizing mathematical operators. Our work that fluidic are promising energy-efficient, long-retention, chips.

Language: Английский

Citations

0

Faraday Lithography DOI

Yuxiang Yin,

Bingyan Liu, Yanru Chen

et al.

Nano Letters, Journal Year: 2025, Volume and Issue: unknown

Published: April 28, 2025

As Moore's Law continues to push critical dimension (CD) scaling in integrated circuits, conventional photolithography approaches fundamental resolution limits. While alternative strategies such as self-aligned double patterning and directed self-assembly address these challenges, they introduce process complexity manufacturing variability. Here we develop Faraday lithography (FL), a novel approach that hybridizes nanoscale 3D printing with nanofabrication overcome limitations. FL achieves remarkable 35 nm features atomic-scale precision (0.95 line edge roughness) excellent local CD uniformity while maintaining simplicity. The technique demonstrates unique capabilities for 2D/3D across diverse substrates, whose conductivity or transparency has no influence. Unlike existing methods, accomplishes this without additional steps complex material requirements. This combination of high resolution, capability, versatility positions both valuable complement current technologies potential catalyst semiconductor nanomanufacturing innovation.

Language: Английский

Citations

0