Viruses,
Journal Year:
2024,
Volume and Issue:
16(1), P. 100 - 100
Published: Jan. 9, 2024
SARS-CoV-2
caused
the
COVID-19
pandemic.
may
elevate
risk
of
cognitive
impairment
and
even
cause
dementia
in
infected
individuals;
it
accelerate
decline
elderly
patients
with
dementia,
possibly
Alzheimer's
disease
(AD)
patients.
However,
mechanisms
underlying
interplay
between
AD
are
still
unclear.
To
investigate
associations
progression
infection,
we
conducted
a
series
bioinformatics
research
into
SARS-CoV-2-infected
cells,
patients,
We
identified
common
differentially
expressed
genes
(DEGs)
these
DEGs
enriched
certain
pathways,
such
as
immune
responses
cytokine
storms.
constructed
gene
interaction
network
signaling
transduction
module
center
Nature Aging,
Journal Year:
2023,
Volume and Issue:
3(6), P. 722 - 733
Published: May 22, 2023
Coronavirus
Disease
2019
(COVID-19)
vaccination
has
resulted
in
excellent
protection
against
fatal
disease,
including
older
adults.
However,
risk
factors
for
post-vaccination
COVID-19
are
largely
unknown.
We
comprehensively
studied
three
large
nursing
home
outbreaks
(20-35%
cases
among
residents)
by
combining
severe
acute
respiratory
syndrome
coronavirus
2
(SARS-CoV-2)
aerosol
monitoring,
whole-genome
phylogenetic
analysis
and
immunovirological
profiling
of
nasal
mucosa
digital
nCounter
transcriptomics.
Phylogenetic
investigations
indicated
that
each
outbreak
stemmed
from
a
single
introduction
event,
although
with
different
variants
(Delta,
Gamma
Mu).
SARS-CoV-2
was
detected
samples
up
to
52
d
after
the
initial
infection.
Combining
demographic,
immune
viral
parameters,
best
predictive
models
mortality
comprised
IFNB1
or
age,
ORF7a
ACE2
receptor
transcripts.
Comparison
published
pre-vaccine
transcriptomic
genomic
signatures
uncovered
unique
IRF3
low/IRF7
high
signature
post-vaccine
outbreaks.
A
multi-layered
strategy,
environmental
sampling,
immunomonitoring
early
antiviral
therapy,
should
be
considered
prevent
homes.
Journal of Global Health,
Journal Year:
2024,
Volume and Issue:
14
Published: March 7, 2024
Despite
numerous
observations
of
neuropsychological
deficits
immediately
following
severe
acute
respiratory
syndrome
coronavirus
2
(SARS-CoV-2)
infection,
little
is
known
about
what
happens
to
these
over
time
and
whether
they
are
affected
by
changes
in
fatigue
any
psychiatric
symptoms.
We
aimed
assess
the
prevalence
at
6-9
months
again
12-15
after
disease
2019
(COVID-19)
explore
it
was
associated
with
Brain Behavior & Immunity - Health,
Journal Year:
2023,
Volume and Issue:
28, P. 100595 - 100595
Published: Jan. 23, 2023
The
objective
of
the
current
investigation
was
to
examine
associations
between
symptomatic
COVID-19
history,
neurocognitive
function,
and
psychiatric
symptoms
using
cognitive
task
performance,
functional
brain
imaging,
a
prospective
population
survey.
Viruses,
Journal Year:
2024,
Volume and Issue:
16(1), P. 100 - 100
Published: Jan. 9, 2024
SARS-CoV-2
caused
the
COVID-19
pandemic.
may
elevate
risk
of
cognitive
impairment
and
even
cause
dementia
in
infected
individuals;
it
accelerate
decline
elderly
patients
with
dementia,
possibly
Alzheimer's
disease
(AD)
patients.
However,
mechanisms
underlying
interplay
between
AD
are
still
unclear.
To
investigate
associations
progression
infection,
we
conducted
a
series
bioinformatics
research
into
SARS-CoV-2-infected
cells,
patients,
We
identified
common
differentially
expressed
genes
(DEGs)
these
DEGs
enriched
certain
pathways,
such
as
immune
responses
cytokine
storms.
constructed
gene
interaction
network
signaling
transduction
module
center
