Cell stem cell, Journal Year: 2024, Volume and Issue: unknown
Published: Oct. 1, 2024
Language: Английский
Cell stem cell, Journal Year: 2024, Volume and Issue: unknown
Published: Oct. 1, 2024
Language: Английский
Journal of Affective Disorders, Journal Year: 2025, Volume and Issue: 378, P. 271 - 280
Published: March 4, 2025
Language: Английский
Citations
1medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 6, 2025
ABSTRACT A deeper understanding of the molecular processes involved in psychological wellbeing older adults is essential for advancing knowledge underlying biological mechanisms. Leveraging proteomics data from 3,262 (mean age=63.5 years, 55% female) English Longitudinal Study Ageing (ELSA), we investigated cross-sectional and longitudinal associations (before after protein measurement) between 276 proteins eudaimonic wellbeing, hedonic life satisfaction, depressive symptoms, over 20-year span. For positive two (DEFB4A ECE1) were longitudinally associated with subsequent trajectory. We further identified higher concentrations 7, 8, 2 linked to lower respectively. Sex differences XCL1 SLAMF7 observed, males. These findings link human regulation several pathways, particularly involving cytokine regulation, neurotrophic signaling, inflammatory immune systems.
Language: Английский
Citations
0Trends in Cognitive Sciences, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
Language: Английский
Citations
0iScience, Journal Year: 2025, Volume and Issue: 28(2), P. 111866 - 111866
Published: Jan. 23, 2025
Language: Английский
Citations
0Trends in Cognitive Sciences, Journal Year: 2024, Volume and Issue: 29(1), P. 85 - 99
Published: Nov. 6, 2024
Language: Английский
Citations
3Cell stem cell, Journal Year: 2024, Volume and Issue: unknown
Published: Oct. 1, 2024
Language: Английский
Citations
2