Small,
Journal Year:
2023,
Volume and Issue:
19(49)
Published: Aug. 17, 2023
Despite
great
advances
in
understanding
the
biological
behaviors
of
chiral
materials,
effect
chirality-configured
nanoparticles
on
tissue
regeneration-related
processes
remains
poorly
understood.
Herein,
chirality
MoS2
quantum
dots
(QDs)
is
tailored
by
functionalization
with
l-/d-penicillamine,
and
profound
effects
QDs
cellular
activities,
angiogenesis,
regeneration
are
thoroughly
investigated.
Specifically,
d-MoS2
show
a
positive
promoting
growth,
proliferation,
migration
human
umbilical
vein
endothelial
cells.
The
expression
vascular
growth
factor
(VEGF),
nitric
oxide
synthase
(eNOS),
fibroblast
(FGF)
group
substantially
up-regulated,
resulting
enhanced
tube
formation
activity.
This
distinct
phenomenon
largely
due
to
higher
internalization
efficiency
than
l-MoS2
chirality-dependent
nano-bio
interactions.
In
vivo
angiogenic
assay
shows
level
markers
newly-formed
skin
tissues
that
group,
leading
an
accelerated
re-epithelialization
improved
regeneration.
findings
angiogenesis
activity
provide
new
insights
into
nanomaterials,
which
also
opens
up
path
rational
design
nanomaterials
for
application.
Micromachines,
Journal Year:
2023,
Volume and Issue:
14(9), P. 1786 - 1786
Published: Sept. 18, 2023
Exploring
bio-inspired
nanomaterials
(BINMs)
and
incorporating
them
into
micro/nanodevices
represent
a
significant
development
in
biomedical
applications.
Nanomaterials,
engineered
to
imitate
biological
structures
processes,
exhibit
distinctive
attributes
such
as
exceptional
biocompatibility,
multifunctionality,
unparalleled
versatility.
The
utilization
of
BINMs
demonstrates
potential
diverse
domains
micro/nanodevices,
encompassing
biosensors,
targeted
drug
delivery
systems,
advanced
tissue
engineering
constructs.
This
article
thoroughly
examines
the
various
BINMs,
including
those
originating
from
proteins,
DNA,
biomimetic
polymers.
Significant
attention
is
directed
toward
these
entities
subsequent
ramifications
that
arise.
review
explores
biomimicry’s
structure–function
correlations.
Synthesis
mosaics
include
bioprocesses,
biomolecules,
natural
structures.
These
nanomaterials’
interfaces
use
functionalization
geometric
adaptations,
transforming
delivery,
nanobiosensing,
organ-on-chip
cancer-on-chip
models,
wound
healing
dressing
mats,
antimicrobial
surfaces.
It
provides
an
in-depth
analysis
existing
challenges
proposes
prospective
strategies
improve
efficiency,
performance,
reliability
devices.
Furthermore,
this
study
offers
forward-thinking
viewpoint
highlighting
avenues
for
future
exploration
advancement.
objective
effectively
utilize
maximize
application
progression
thereby
propelling
rapidly
developing
field
its
promising
future.
Advanced Materials,
Journal Year:
2024,
Volume and Issue:
36(18)
Published: Jan. 19, 2024
Abstract
Machine
learning
holds
significant
research
potential
in
the
field
of
nanotechnology,
enabling
nanomaterial
structure
and
property
predictions,
facilitating
materials
design
discovery,
reducing
need
for
time‐consuming
labor‐intensive
experiments
simulations.
In
contrast
to
their
achiral
counterparts,
application
machine
chiral
nanomaterials
is
still
its
infancy,
with
a
limited
number
publications
date.
This
despite
great
advance
development
new
sustainable
high
values
optical
activity,
circularly
polarized
luminescence,
enantioselectivity,
as
well
analysis
structural
chirality
by
electron
microscopy.
this
review,
an
methods
used
studying
provided,
subsequently
offering
guidance
on
adapting
extending
work
nanomaterials.
An
overview
within
framework
synthesis–structure–property–application
relationships
presented
insights
how
leverage
study
these
highly
complex
are
provided.
Some
key
recent
reviewed
discussed
Finally,
review
captures
achievements,
ongoing
challenges,
prospective
outlook
very
important
field.
Journal of the American Chemical Society,
Journal Year:
2024,
Volume and Issue:
146(15), P. 10640 - 10654
Published: April 3, 2024
Foreign
ions
as
additives
are
of
great
significance
for
realizing
excellent
control
over
the
morphology
noble
metal
nanostructures
in
state-of-the-art
seed-mediated
growth
method;
however,
they
remain
largely
unexplored
chiral
synthesis.
Here,
we
report
on
a
Cu2+-dominated
strategy
that
can
direct
concave
Au
nanoparticles
with
C3-dominant
centers.
The
introduction
trace
amounts
Cu2+
process
is
found
to
dominate
chirality
transfer
from
molecules
nanoparticles,
leading
formation
VC
geometry.
Both
experimental
and
theoretical
results
further
demonstrate
correlation
between
nanoparticle
structure
optical
nanoparticle.
ion
by
selectively
activating
deposition
atoms
along
[110]
[111]
directions,
facilitating
VC.
We
be
employed
generate
variety
enriched
geometric
desired
chiroptical
properties.
Concave
also
exhibit
appealing
catalytic
activity
selectivity
toward
electrocatalytic
oxidation
enantiomers
comparison
helicoidal
nanoparticles.
ability
tune
controlled
manner
simply
manipulating
opens
up
promising
creating
nanomaterials
increasing
architectural
diversity
chirality-dependent
applications.
Nature Communications,
Journal Year:
2024,
Volume and Issue:
15(1)
Published: April 25, 2024
Abstract
Asymmetric
transformations
and
synthesis
have
garnered
considerable
interest
in
recent
decades
due
to
the
extensive
need
for
chiral
organic
compounds
biomedical,
agrochemical,
chemical,
food
industries.
The
field
of
inorganic
catalysts,
garnering
its
contributions
asymmetric
transformations,
has
witnessed
remarkable
advancements
emerged
as
a
highly
innovative
research
area.
Here,
we
review
latest
developments
this
dynamic
emerging
comprehensively
understand
advances
nanocatalysts
stimulate
further
progress
catalysis.
ACS Nano,
Journal Year:
2024,
Volume and Issue:
18(13), P. 9543 - 9556
Published: March 22, 2024
Chirality
transfer
from
chiral
molecules
to
nanomaterials
represents
an
important
topic
for
exploring
the
origin
of
chirality
in
many
natural
and
artificial
systems.
Moreover,
developing
a
promising
class
holds
great
significance
various
applications,
including
sensing,
photonics,
catalysis,
biomedicine.
Here
we
demonstrate
geometric
control
tunable
optical
pentatwinned
Au
nanoparticles
with
5-fold
rotational
symmetry
using
seed-mediated
growth
method.
A
distinctive
pathway
are
observed
decahedra
as
seeds,
comparison
single-crystal
seeds.
By
employing
different
peptides
inducers,
two
distinct
(pentagonal
nanostars
pentagonal
prisms)
obtained.
The
intriguing
formation
evolution
twinned
structure
analyzed
crystallographic
perspective
upon
maneuvering
interplay
molecules,
surfactants,
reducing
agents.
interesting
effects
molecular
on
tuning
also
explored.
Finally,
theoretically
experimentally
investigate
far-field
near-field
properties
through
numerical
simulations
single-particle
chiroptical
measurements.
ability
tune
controlled
manner
step
toward
development
increasing
architectural
complexity
applications.
ACS Nano,
Journal Year:
2023,
Volume and Issue:
18(1), P. 641 - 651
Published: Dec. 19, 2023
Titanium
dioxide
(TiO2)
has
attracted
significant
attention
in
the
fields
of
antibacterial
activity
and
pollutant
degradation
due
to
its
well-known
photocatalytic
properties.
However,
application
TiO2
is
significantly
limited
by
large
band
gap
width,
which
only
allows
excitation
ultraviolet
light
below
400
nm.
Here,
we
propose
use
surface
chiral
functionalization
tune
thus
enabling
it
be
excited
near-infrared-region
(NIR),
resulting
effective
separation
electron–hole
pairs.
By
controlling
solvent
polarity
forming
numerous
weak
interactions
(such
as
hydrogen
bonding)
between
ligands
TiO2,
successfully
prepared
superparticles
(SPs)
that
exhibited
a
broad
circular
dichroism
(CD)
absorption
at
792
Under
circularly
polarized
(CPL)
808
nm,
SPs
induced
pairs
generating
hydroxyl
singlet
oxygen
radicals.
Antibacterial
tests
under
CPL
NIR
showed
excellent
performance,
with
inhibition
rates
99.4%
100%
against
Gram-positive
Gram-negative
bacteria,
respectively.
Recycling–reuse
experiments
biocompatibility
evaluation
material
demonstrated
are
stable
safe
materials,
indicating
potential
aspects
medical
implants.
Advanced Functional Materials,
Journal Year:
2023,
Volume and Issue:
34(10)
Published: Nov. 29, 2023
Abstract
Here,
the
development
of
chiral
D
‐/
L
‐Cu
x
OS
nanoparticle‐engineered
metal–organic
frameworks
(Fe‐MIL‐88B‐NH
2
),
denoted
as
OS@Fe‐MOFs,
for
cuproptosis
and
ferroptosis
synergistic
therapy
is
described.
The
OS@Fe‐MOF
displayed
intense
circular
dichroism
(CD)
bands
at
488
nm
due
to
chirality
transfer
from
penicillamine
ligands.
Chiral
showed
tumor
microenvironment‐triggered
catalytic
therapeutic
activity
by
simultaneously
depleting
‐glutathione
(GSH)
generating
potent
reactive
oxygen
species
in
cancer
cells.
In
vivo
experimental
results
synchronously
demonstrated
with
higher
efficiency
therapy.
findings
revealed
that
copper/iron
ions
released
induced
augmented
oxidative
stress
ferroptosis,
which
synergizes
enhanced
index
determined
be
1.94,
while
D,L
1.75
1.84,
respectively.
To
best
knowledge,
this
first
report
a
nanomaterial
capable
inducing
ferroptosis‐cuproptosis
cancers.
should
invigorate
studies
pursuing
rational
design
nanomaterials
efficacious
based
on
ferroptosis.
ACS Nano,
Journal Year:
2024,
Volume and Issue:
18(20), P. 12589 - 12597
Published: May 6, 2024
Circular
polarization-resolved
Raman
scattering
methods
include
optical
activity
(ROA)
and
its
derivative─surface-enhanced
(SEROA).
These
spectroscopic
modalities
are
rapidly
developing
due
to
their
high
information
content,
stand-off
capabilities,
rapid
development
of
Raman-active
chiral
nanostructures.
enable
a
direct
readout
the
vibrational
energy
levels
molecules,
crystals,
nanostructured
materials,
making
it
possible
study
complex
interactions
dynamic
interfaces
between
them.
They
were
shown
be
particularly
valuable
for
nano-
biotechnological
fields
encompassing
particles
with
nanoscale
chirality
that
combine
strong
intense
polarization
rotation.
This
perspective
dives
into
recent
advancements
in
ROA
SEROA,
distinction
from
surface-enhanced
scattering,
potential
these
information-rich
label-free
spectroscopies
detection
biomolecules.
