Perspective Chapter: Molecular Diagnostics in Viral Outbreak Surveillance DOI
Jennifer Giandhari, Amsha Viraragavan, Michelle Gordon

et al.

IntechOpen eBooks, Journal Year: 2025, Volume and Issue: unknown

Published: April 16, 2025

Understanding and adopting various methods for monitoring viral outbreaks is required pathogen surveillance. Accurate diagnosis can play a significant role in the safe effective treatment prescribed. Africa remains burdened with host of infectious diseases, which challenges healthcare systems proper management diseases. Surveillance are implemented some parts that have infrastructure funding to perform routine testing screening. However, not all this continent equipped necessary tools support. With travel, tourism goods exchange, diseases spread across borders rapidly, posing threat global health, emphasising unified need efforts prevent, detect, act on disease through improved access vaccinations treatments. Effective response depends several elements, including laboratory capacity, skilled health staff, surveillance detect limit illnesses rapidly. Traditional molecular such as genotyping polymerase chain reaction (PCR)-based detection now being complemented like next-generation sequencing clustered regularly interspaced short palindromic repeats (CRISPR). This book chapter aims summarise current broadly describes issue climate change its impact outbreaks.

Language: Английский

Frontiers in superbug management: innovating approaches to combat antimicrobial resistance DOI
Priyanka Chambial, Neelam Thakur, Prudhvi Lal Bhukya

et al.

Archives of Microbiology, Journal Year: 2025, Volume and Issue: 207(3)

Published: Feb. 14, 2025

Language: Английский

Citations

0
Bioconvergence and Non‐Human Primate Models in Human Metapneumovirus Research DOI
Taeho Kwon

Journal of Medical Primatology, Journal Year: 2025, Volume and Issue: 54(2)

Published: Feb. 26, 2025

ABSTRACT Human metapneumovirus (HMPV) poses a significant global health threat. While nonhuman primates (NHPs) remain crucial models, ethical and economic limitations necessitate complementary approaches. Advanced bioconvergence technologies, including organoids, artificial intelligence (AI), quantum computing, offer scalable, cost‐effective, solutions, enhancing HMPV research, antiviral development, future clinical applications.

Language: Английский

Citations

0
Multi-Pathway Study for Oxaliplatin Resistance Reduction DOI Creative Commons
Tong Ye,

Chen Wu,

Jintong Na

et al.

Current Issues in Molecular Biology, Journal Year: 2025, Volume and Issue: 47(3), P. 172 - 172

Published: March 4, 2025

Chemotherapy for cancer frequently uses platinum-based medications, including oxaliplatin, carboplatin, and cisplatin; however, due to their high systemic toxicity, lack of selectivity, drug resistance, other side effects, medications have very limited clinical application. As a first-line medication in antitumor therapy, oxaliplatin must be administered minimize effects while achieving anticancer objectives. A new CDC7 inhibitor called XL413 has demonstrated promising therapeutic variety malignant tumors may properties. This offers fresh viewpoint on how lessen resistance and, specifically, increase the potency already prescribed therapies. In this paper, current developments therapy are discussed, along with many mechanisms oxaliplatin’s treatment challenges, related approaches. We conducted more research that arose during chemotherapy searched ways it order enhance its chemotherapeutic performance. Ultimately, we studied distinct routes relate one another. Meanwhile, XL413, novel inhibitor, perspective possibilities developing approaches innovation point. The search terms “Oxaliplatin, treatment,” etc., were applied X-MOL PubMed databases review’s literature search. Boolean logic was then employed maximize approach. These can offer thorough data cover broad range biological publications. Excluded publications works low relevance, duplicates, or those insufficient information. mechanism effect, amelioration, role main topics 140 ultimately included analysis.

Language: Английский

Citations

0
Cutting-edge AI tools revolutionizing scientific research in life sciences DOI Creative Commons

Katarzyna Lorenc-Kukula

BioTechnologia, Journal Year: 2025, Volume and Issue: unknown

Published: March 7, 2025

Artificial intelligence (AI) is becoming a transformative force in the life sciences, pushing boundaries of possibility. Imagine AI automating time-consuming tasks, uncovering hidden patterns vast datasets, designing proteins minutes instead years, and even predicting disease outbreaks before they occur. This review explores latest tools revolutionizing scientific fields, including research data analysis, healthcare, supporting writing. Beyond processing, reshaping how scientists draft share their findings, enhancing processes ranging from literature reviews to citation management. However, with great power comes responsibility. Are we prepared for this leap? delves into forefront where innovation meets

Language: Английский

Citations

0
Exploring the Intricacies of Antimicrobial Resistance: Understanding Mechanisms, Overcoming Challenges, and Pioneering Innovative Solutions DOI

Shahbaz Ul Haq,

Lingchong Wang, Amjad Islam Aqib

et al.

European Journal of Pharmacology, Journal Year: 2025, Volume and Issue: unknown, P. 177511 - 177511

Published: March 1, 2025

Language: Английский

Citations

0
Artificial intelligence and its application in clinical microbiology DOI
Assia Mairi,

Lamia Hamza,

Abdelaziz Touati

et al.

Expert Review of Anti-infective Therapy, Journal Year: 2025, Volume and Issue: unknown

Published: March 25, 2025

Traditional microbiological diagnostics face challenges in pathogen identification speed and antimicrobial resistance (AMR) evaluation. Artificial intelligence (AI) offers transformative solutions, necessitating a comprehensive review of its applications, advancements, integration clinical microbiology. This examines AI-driven methodologies, including machine learning (ML), deep (DL), convolutional neural networks (CNNs), for enhancing detection, AMR prediction, diagnostic imaging. Applications virology (e.g. COVID-19 RT-PCR optimization), parasitology malaria detection), bacteriology automated colony counting) are analyzed. A literature search was conducted using PubMed, Scopus, Web Science (2018-2024), prioritizing peer-reviewed studies on AI's accuracy, workflow efficiency, validation. AI significantly improves precision operational efficiency but requires robust validation to address data heterogeneity, model interpretability, ethical concerns. Future success hinges interdisciplinary collaboration develop standardized, equitable tools tailored global healthcare settings. Advancing explainable federated frameworks will be critical bridging current implementation gaps maximizing potential combating infectious diseases.

Language: Английский

Citations

0
Perspective Chapter: Molecular Diagnostics in Viral Outbreak Surveillance DOI
Jennifer Giandhari, Amsha Viraragavan, Michelle Gordon

et al.

IntechOpen eBooks, Journal Year: 2025, Volume and Issue: unknown

Published: April 16, 2025

Understanding and adopting various methods for monitoring viral outbreaks is required pathogen surveillance. Accurate diagnosis can play a significant role in the safe effective treatment prescribed. Africa remains burdened with host of infectious diseases, which challenges healthcare systems proper management diseases. Surveillance are implemented some parts that have infrastructure funding to perform routine testing screening. However, not all this continent equipped necessary tools support. With travel, tourism goods exchange, diseases spread across borders rapidly, posing threat global health, emphasising unified need efforts prevent, detect, act on disease through improved access vaccinations treatments. Effective response depends several elements, including laboratory capacity, skilled health staff, surveillance detect limit illnesses rapidly. Traditional molecular such as genotyping polymerase chain reaction (PCR)-based detection now being complemented like next-generation sequencing clustered regularly interspaced short palindromic repeats (CRISPR). This book chapter aims summarise current broadly describes issue climate change its impact outbreaks.

Language: Английский

Citations

0