Biomaterial-based drug delivery systems in the treatment of inner ear disorders DOI Creative Commons
Hong Cheng, Bin Zhang, Pei Jiang

et al.

Journal of Nanobiotechnology, Journal Year: 2025, Volume and Issue: 23(1)

Published: April 17, 2025

Inner ear disorders are among the predominant etiology of hearing loss. The blood-labyrinth barrier limits ability drugs to attain pharmacologically effective concentrations within inner ear; consequently, delivering systemically is insufficient for effectively treating disorders. Hence, it imperative create efficient, minimal or non-invasive methods administering ear. However, development such a system hindered by three main factors: anatomical unavailability, lack sustained drug delivery, and individual variability. Advances in biomaterials technology have created new opportunities overcoming existing barriers, offering great hope treatment Hydrogel- nanoparticle-based delivery systems can carry targeted designated locations long-term, release. Furthermore, range devices, including microneedles, micropumps, cochlear implants, when paired with biomaterials, enhance ear, making more effective. Therefore, biomaterial-based offer possibility extensive clinical uses promise restore millions patients

Language: Английский

Bioinspired superwetting oil–water separation strategy: toward the era of openness DOI

Zhuoxing Liu,

Yifan Si, Cunlong Yu

et al.

Chemical Society Reviews, Journal Year: 2024, Volume and Issue: 53(20), P. 10012 - 10043

Published: Jan. 1, 2024

Bioinspired superwetting oil–water separation strategy is summarized from confined-space to open-space, static dynamic devices. Strategies are evaluated and compared current challenges feasible solutions emphasized.

Language: Английский

Citations

23

Interfacial fluid manipulation with bioinspired strategies: special wettability and asymmetric structures DOI
Haoyu Bai, Tianhong Zhao, Moyuan Cao

et al.

Chemical Society Reviews, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Bioinspired fluid manipulating interfaces possessing special wettability, an asymmetric structure, and a geometric gradient were systematically reviewed, including history, classification, mechanisms, fabrication applications.

Language: Английский

Citations

5

Phase Separation Derived Anisotropic Adhesive Structural Color Hydrogel Films For Flexible Electronics DOI
Yu Wang, Yi Cheng, Lijun Cai

et al.

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: 34(46)

Published: June 28, 2024

Abstract Hydrogels hold great promise in the field of flexible electronics. Attempts this area tend to microstructure design hydrogels, giving them specific adhesion and multi‐sensing functions. Here, a novel phase separation‐derived anisotropic adhesive structural color hydrogel film is presented for visually The generated by template replicating colloidal crystal using separation emulsions hydrophilic monomer (acrylic acid, AA), hydrophobic (lauryl methacrylate, LMA), co‐monomer ([2‐(methacryloyloxy) ethyl] dimethyl‐(3‐sulfopropyl) ammonium hydroxide (SBMA)), surfactants (hexadecyl trimethyl bromide, CTAB) initiator (ammonium persulphate (APS)). appearance results asymmetric morphologies film, imparting with performance. Attributed formation inverse opal scaffold structure, featured vivid color, showing superior capability self‐reporting mechanical behavior. Additionally, benefitting from presence abundant ions, exhibits conductivity. Thus, resultant demonstrated stable dual‐signal sensing properties involving color‐changing conductivity feedback ability respond human activities. These features make proposed highly potential electronic field.

Language: Английский

Citations

11

Liquid metal hybrid antibacterial hydrogel scaffolds from 3D printing for wound healing DOI
Jinbo Li, Yu Wang, Lu Fan

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 496, P. 153805 - 153805

Published: July 7, 2024

Language: Английский

Citations

11

Flexible liquid-diode microtubes from multimodal microfluidics DOI Creative Commons
Chaoyu Yang, Wenzhao Li, Yuanjin Zhao

et al.

Proceedings of the National Academy of Sciences, Journal Year: 2024, Volume and Issue: 121(28)

Published: July 3, 2024

Directional transport of liquids is great importance in energy saving, chemical/biomedical engineering, and microfluidics applications. Despite considerable progress engineering different open surfaces to achieve liquid manipulation, the realization diode-like enclosed spaces still challenging. Here, a flexible diode microtube presented for directional within confined using pulsed microfluidics. The microtubes exhibit sophisticated microstructures on inner wall, replicated from precisely controlled flow configuration microfluidic channel. Under effect asymmetric pinning unbalanced Laplace pressure, such enable closed channels. More importantly, by integrating situ lithography with system, segmented diodes are fabricated as assembly units construction fluidic–electronic circuits that perform logic operations. These results demonstrate capacity present liquid-diode flexible, directional, programmable transport. We believe it can an avenue designing advanced fluidic circuit-based devices toward versatile practical

Language: Английский

Citations

10

Structural Color Colloidal Photonic Crystals for Biomedical Applications DOI Creative Commons

Wenhui Zhang,

Yangnan Hu, Pan Feng

et al.

Advanced Science, Journal Year: 2024, Volume and Issue: unknown

Published: July 31, 2024

Photonic crystals are a new class of optical microstructure materials characterized by dielectric constant that varies periodically with space and features photonic bandgap. Inspired natural such as butterfly scales, series artificial developed for use in integrated platforms, biosensing, communication, other fields. Among them, colloidal (CPCs) have gained widespread attention due to their excellent properties advantages, ease preparation functionalization. This work reviews the classification self-assembly principles CPCs, details some latest biomedical applications large-area, high-quality CPCs prepared using advanced methods, summarizes existing challenges CPC construction application, anticipates future development directions optimization strategy. With further advancements, expected play more critical role biosensors, drug delivery, cell research, fields, bringing significant benefits research clinical practice.

Language: Английский

Citations

10

Hydrogel-based hollow microfibers for functional esophageal carcinoma remodeling DOI Creative Commons

Linlin Shi,

Siyu Hao,

Jun Li

et al.

Cell Reports Physical Science, Journal Year: 2025, Volume and Issue: unknown, P. 102358 - 102358

Published: Jan. 1, 2025

Language: Английский

Citations

1

Developing 3D bioprinting for organs-on-chips DOI
Zhuhao Wu, Rui Liu, Ning Shao

et al.

Lab on a Chip, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Organs-on-chips (OoCs) can be directly fabricated by 3D bioprinting techniques, which enhance the structural and functional fidelity of organ models broaden applications OoCs.

Language: Английский

Citations

1

Magnetic structural color microspheres for the multiplex detection of acute kidney injury biomarkers DOI
Haiwen Su,

Haoyu Ren,

Zhihong Xuan

et al.

Analytica Chimica Acta, Journal Year: 2025, Volume and Issue: 1346, P. 343767 - 343767

Published: Feb. 3, 2025

Language: Английский

Citations

1

Developing mRNA Nanomedicines with Advanced Targeting Functions DOI Creative Commons
Ji Wang, Lijun Cai, Ning Li

et al.

Nano-Micro Letters, Journal Year: 2025, Volume and Issue: 17(1)

Published: Feb. 21, 2025

The emerging messenger RNA (mRNA) nanomedicines have sprung up for disease treatment. Developing targeted mRNA has become a thrilling research hotspot in recent years, as they can be precisely delivered to specific organs or tissues enhance efficiency and avoid side effects. Herein, we give comprehensive review on the latest progress of with targeting functions. its carriers are first described detail. Then, mechanisms passive targeting, endogenous active outlined, focus various biological barriers that may encounter during vivo delivery. Next, emphasis is placed summarizing mRNA-based organ-targeting strategies. Lastly, advantages challenges clinical translation mentioned. This expected inspire researchers this field drive further development technology.

Language: Английский

Citations

1