Nanophotonic-enhanced photoacoustic imaging for brain tumor detection

Journal of Nanobiotechnology, Journal Year: 2025, Volume and Issue: 23(1)

Published: March 5, 2025

Photoacoustic brain imaging (PABI) has emerged as a promising biomedical modality, combining high contrast of optical with deep tissue penetration ultrasound imaging. This review explores the application photoacoustic in tumor imaging, highlighting synergy between nanomaterials and state art techniques to achieve high-resolution deeper tissues. PABI leverages effect, where absorbed light energy causes thermoelastic expansion, generating waves that are detected converted into images. technique enables precise diagnosis, therapy monitoring, enhanced clinical screening, specifically management complex diseases such breast cancer, lymphatic disorder, neurological conditions. Despite integration agents radiation, providing comprehensive overview current methodologies, major obstacles treatment, future directions for improving diagnostic therapeutic outcomes. The underscores significance robust research tool medical method, potential revolutionize disease diagnosis treatment.

Language: Английский

Permittivity-asymmetric chiral metasurfaces empowered by bound states in the continuum

Frontiers in Physics, Journal Year: 2025, Volume and Issue: 13

Published: April 2, 2025

The intrinsic chirality of natural materials is usually weak or absent. To enlarge circular dichroism, chiral metasurfaces supporting bound states in the continuum have been widely investigated. These demonstrated considerable potential to achieve high quality (Q) factors but require ultra-small structure asymmetry and complicated fabrication processes. Here we propose a novel approach break in-plane symmetry by introducing refractive index perturbations. Furthermore, demonstrate efficient emission from resonant which are composed two slant titanium dioxide (TiO 2 ) bars arranged on square lattice. Numerical calculations indicate that our at normal incidence achieves near-unity dichroism 0.99 an ultra-high Q factor exceeding 106 . relationship between perturbations CD has also studied, offering flexibility enhance tailor simultaneously. Our may lead applications lasers, light detectors, biosensing, nonlinear filters.

Language: Английский

Chirality Quantification for High‐Performance Nanophotonic Biosensors

Small Methods, Journal Year: 2025, Volume and Issue: unknown

Published: April 8, 2025

Abstract Recent advancements in chiral metabolomics have facilitated the discovery of disease biomarkers through enantioselective measurement metabolites, offering new opportunities for diagnosis, prognosis, and personalized medicine. Although photonic nanomaterials emerged as promising platforms biosensing, enhancing sensitivity enabling detection biomolecules at extremely low concentrations, a deeper understanding relationship between structural optical chirality is crucial optimizing these platforms. This perspective examines recent methods quantifying chirality, including Hausdorff Chirality Measure (HCM), Continuous (CCM), Osipov‐Pickup‐Dunmur (OPD), Graph‐Theoretical (GTC) measure. These approaches advanced both materials biomolecules, well its correlation with responses. work emphasizes role quantification improving biosensor performance explores potential near‐field chiroptical studies to enhance sensor capabilities. Finally, this addresses key challenges outline future research directions advancing biosensors, focus on nano‐bio interface interactions drive development next‐generation sensing technologies.

Language: Английский