Organic & Biomolecular Chemistry,
Journal Year:
2019,
Volume and Issue:
17(42), P. 9390 - 9402
Published: Jan. 1, 2019
Diastereoselective
[3
+
2]-cycloadditions
of
oxindoles
with
α,β-disubstituted
nitroethylenes:
regioreversed
spiropyrrolidines
show
potent
MRSA
activity.
Current Green Chemistry,
Journal Year:
2020,
Volume and Issue:
7(1), P. 53 - 104
Published: Feb. 18, 2020
:
Nanoparticle
catalyzed
synthesis
is
a
green
and
convenient
method
to
achieve
most
of
the
chemical
transformations
in
water
or
other
solvents.
ensures
an
easy
isolation
process
catalyst
as
well
products
from
reaction
mixture
avoiding
hectic
work
up
procedure.
Zinc
oxide
biocompatible,
environmentally
benign
economically
viable
nanocatalyst
with
effectivity
comparable
metal
employed
several
strategies.
This
review
mainly
focuses
on
recent
applications
zinc
biologically
important
heterocyclic
molecules
under
sustainable
conditions.
Application
organic
synthesis:
Considering
achievable
advantages
this
nanocatalyst,
presently
research
groups
are
paying
attention
anchoring
zincoxide
its
modified
structure
types
conversions
e.g.
multicomponent
reactions,
ligand-free
coupling
cycloaddition
reaction,
etc.
The
limitations
also
demonstrated.
present
study
aims
highlight
multifaceted
ZnO
towards
diverse
motifs.
Being
promising
biocompatible
nanoparticle,
has
contribution
fields
synthetic
chemistry
medicinal
chemistry.
Copper
is
an
abundant,
low
cost,
and
redox-plural
(0/I/II/III)
transition
element,
frequently,
its
salts
or
complexes
are
used
for
efficient
molecular
transformations
of
natural
products,
bioactive
molecules,
agrochemicals,
organic
functional
materials,
thus
representing
ideal
candidate
developing
sustainable
metal-based
catalytic
protocols.
Current,
green,
process
development
trends
involve
alternate
energy
inputs
(e.g.
microwaves
sources
in
mechanochemistry
photochemistry)
produce
chemicals
with
the
utmost
level
waste
minimisation.
This
work
details
recent
copper-based
methodologies
that
yield
scaffolds
high
pharmaceutical
importance,
such
as
but
not
limited
to
propargylamines,
pyrroles,
dihydropyridines.
The Chemical Record,
Journal Year:
2024,
Volume and Issue:
24(11)
Published: Oct. 21, 2024
Abstract
Pyrrole‐embedded
organic
molecules
received
a
considerable
importance
due
to
their
numerous
biological
and
material
applications.
Hence,
several
synthetic
strategies
have
been
devised
for
the
construction
of
diverse
pyrrole
analogues
over
years.
Among
these,
Clauson‐Kaas
reaction
is
one
most
widely
used
protocols
synthesis
various
N
‐substituted
pyrroles.
This
review
briefly
describes
along
with
modifications
detailed
account
on
its
applications
in
sectors
synthesis.
