A facile pseudo three component reaction for the synthesis of benzo [4,5]imidazo[1,2-a]pyridine derivatives DOI Creative Commons

G. Vasuki,

Natarajan Nithya

MOJ Bioorganic & Organic Chemistry, Journal Year: 2018, Volume and Issue: 2(4)

Published: Aug. 15, 2018

Background: Benzo[4,5]imidazo[1,2-a]pyridine derivatives were accessed through an efficient pseudo three component reaction between dialdehydes such as o-phthalaldehyde, glutaraldehyde, 2,3-thiophenedicarboxaldehyde and the active methylene 2-(1H-benzo[d]imidazol-2-yl)acetonitrile.The products obtained in a one-pot manner with easy purification further characterized by NMR, FT-IR HRMS spectral data (Figure 1).. Figure 1 Benzo [4,5]imidazo[1,2-a]pyridine.

Language: Английский

review on green multicomponent synthesis of heterocyclic compounds DOI Open Access

Alphonsus D’souza,

Agnes Sylvia D’Souza,

Archana Priyanka Mendonca

et al.

International Journal of Health Sciences, Journal Year: 2022, Volume and Issue: unknown, P. 4601 - 4623

Published: Oct. 6, 2022

Heterocyclic compounds are of very much concern in our daily life. These constitute the largest and most varied family organic compounds. have one or more hetero atoms their structure., Day by day number is increasing rapidly due to enormous synthetic research also utility. They may be cyclic non-cyclic nature. predominantly used as pharmaceuticals, agrochemicals veterinary products. find applications sanitizers, developers, antioxidants, corrosion inhibitors, copolymers, dye stuff anticancer drugs. vehicles synthesis other In this review, we cover biological active heterocyclic that it’s recently synthesized extracted from plants e.g. antibiotics such penicillin’s, cephalosporin; alkaloids vinblastine, morphine, reserpine etc. moiety.

Language: Английский

Citations

1
ChemInform Abstract: Green Chemistry Oriented Multi‐Component Strategy to Hybrid Heterocycles. DOI

Balakrishnan Rajarathinam,

Kandhasamy Kumaravel,

G. Vasuki

et al.

ChemInform, Journal Year: 2016, Volume and Issue: 47(51)

Published: Dec. 1, 2016

Abstract A hybrid heterocyclic scaffold possessing two biologically active moieties with contiguous stereo centers, is accessed in good yields by a catalyst‐free three‐component reaction water at ambient temperature from simple educts.

Language: Английский

Citations

0
Diversity-Oriented Synthesis of Chromenes DOI
Atul Kumar,

Diksha Rajput,

Gowsia Jan

et al.

BENTHAM SCIENCE PUBLISHERS eBooks, Journal Year: 2023, Volume and Issue: unknown, P. 43 - 83

Published: Aug. 7, 2023

Diversity-oriented synthesis (DOS) plays an important role in the construction of various natural products and development diverse small molecules biological significance. In recent years, numerous diversity-oriented approaches have been demonstrated to furnish complex structures with molecular diversity from readily accessible starting materials. This chapter summarizes based on metal-free, transition metal-catalyzed, organocatalyzed reactions for chromene derivatives.

Language: Английский

Citations

0
A facile pseudo three component reaction for the synthesis of benzo [4,5]imidazo[1,2-a]pyridine derivatives DOI Creative Commons

G. Vasuki,

Natarajan Nithya

MOJ Bioorganic & Organic Chemistry, Journal Year: 2018, Volume and Issue: 2(4)

Published: Aug. 15, 2018

Background: Benzo[4,5]imidazo[1,2-a]pyridine derivatives were accessed through an efficient pseudo three component reaction between dialdehydes such as o-phthalaldehyde, glutaraldehyde, 2,3-thiophenedicarboxaldehyde and the active methylene 2-(1H-benzo[d]imidazol-2-yl)acetonitrile.The products obtained in a one-pot manner with easy purification further characterized by NMR, FT-IR HRMS spectral data (Figure 1).. Figure 1 Benzo [4,5]imidazo[1,2-a]pyridine.

Language: Английский

Citations

0