Advanced Functional Materials,
Journal Year:
2023,
Volume and Issue:
33(46)
Published: July 9, 2023
Abstract
Skin
photodamage,
which
is
induced
by
ultraviolet
(UV)
radiation,
a
prevalent
cause
of
skin
damage.
In
this
study,
transdermal
drug
delivery
system
developed
for
the
topical
treatment
composed
tetrahedral
framework
nucleic
acids
(tFNAs)
and
lipoic
acid
(LA).
The
tFNAs‐LA
(TLA)
nanocomposite
exhibits
excellent
biocompatibility,
as
well
antioxidant,
anti‐apoptotic,
anti‐inflammatory
capabilities.
tFNA,
carrier,
facilitates
TLA
cell
entry
penetration,
while
loaded
LA
enhances
antioxidant
photodamaged
human
dermal
fibroblast
(HDF),
promotes
proliferation
migration
inhibiting
apoptosis
activation
reactive
oxygen
species
production.
Moreover,
modulates
apoptosis‐related
proteins
NF‐κB
signaling
pathways,
increasing
cellular
secretion
suppressing
inflammatory
responses
in
HDF
cells.
vivo
experiment,
application
tissue
healing
skin,
regulates
expression
inflammation
collagen‐related
proteins.
It
suggested
that
ability
enables
non‐invasive
therapy
highlighting
potential
employing
acid‐based
systems
disease.
International Journal of Molecular Sciences,
Journal Year:
2023,
Volume and Issue:
24(18), P. 13874 - 13874
Published: Sept. 9, 2023
Phenolic
compounds
or
polyphenols
are
among
the
most
common
of
secondary
metabolism
in
plants.
Their
biosynthesis
is
characteristic
all
plant
cells
and
carried
out
with
participation
shikimate
acetate-malonate
pathways.
In
this
case,
various
structures
formed,
such
as
phenylpropanoids,
flavonoids,
oligomeric
polymeric
phenolic
nature.
number
already
exceeds
10,000.
The
diversity
phenolics
affects
their
biological
activity
functional
role.
Most
representatives
characterized
by
interaction
reactive
oxygen
species,
which
manifests
itself
not
only
plants
but
also
human
body,
where
they
enter
through
food
chains.
Having
a
high
activity,
successfully
used
medicines
nutritional
supplements
for
health
population.
accumulation
depend
on
many
factors,
including
physiological-biochemical,
molecular-genetic,
environmental
factors.
review,
we
present
latest
literature
data
structure
classes
compounds,
antioxidant
biosynthesis,
molecular
genetic
aspects
(genes
transfactors).
Since
grow
significant
changes
planet,
response
to
action
abiotic
factors
(light,
UV
radiation,
temperature,
heavy
metals)
at
level
composition
these
metabolites,
well
metabolic
regulation,
considered.
Information
given
about
important
necessary
components
nutrition
pharmaceutically
valuable
substances
Proposals
promising
areas
research
development
field
presented.
Photochemical & Photobiological Sciences,
Journal Year:
2022,
Volume and Issue:
21(3), P. 275 - 301
Published: Feb. 21, 2022
Abstract
The
Environmental
Effects
Assessment
Panel
of
the
Montreal
Protocol
under
United
Nations
Environment
Programme
evaluates
effects
on
environment
and
human
health
that
arise
from
changes
in
stratospheric
ozone
layer
concomitant
variations
ultraviolet
(UV)
radiation
at
Earth’s
surface.
current
update
is
based
scientific
advances
have
accumulated
since
our
last
assessment
(Photochem
Photobiol
Sci
20(1):1–67,
2021).
We
also
discuss
how
climate
change
affects
depletion
radiation,
change.
resulting
interlinking
depletion,
UV
are
assessed
terms
air
quality,
carbon
sinks,
ecosystems,
health,
natural
synthetic
materials.
further
highlight
potential
impacts
biosphere
extreme
events
occurring
with
increasing
frequency
as
a
consequence
These
other
interactive
examined
respect
to
benefits
its
Amendments
providing
life
Earth
by
controlling
production
various
substances
contribute
both
Photochemical & Photobiological Sciences,
Journal Year:
2023,
Volume and Issue:
22(5), P. 937 - 989
Published: April 21, 2023
This
assessment
provides
a
comprehensive
update
of
the
effects
changes
in
stratospheric
ozone
and
other
factors
(aerosols,
surface
reflectivity,
solar
activity,
climate)
on
intensity
ultraviolet
(UV)
radiation
at
Earth's
surface.
The
is
performed
context
Montreal
Protocol
Substances
that
Deplete
Ozone
Layer
its
Amendments
Adjustments.
Changes
UV
low-
mid-latitudes
(0-60°)
during
last
25
years
have
generally
been
small
(e.g.,
typically
less
than
4%
per
decade,
increasing
some
sites
decreasing
others)
were
mostly
driven
by
cloud
cover
atmospheric
aerosol
content,
caused
partly
climate
change
measures
to
control
tropospheric
pollution.
Without
Protocol,
erythemal
(sunburning)
irradiance
northern
southern
latitudes
50°
would
increased
10-20%
between
1996
2020.
For
exceeding
50°,
Index
(UVI)
surged
25%
(year-round
tip
South
America)
more
100%
(South
Pole
spring).
Variability
Antarctica
was
very
large
four
years.
In
spring
2019,
minimum
historical
(1991-2018)
range
Pole,
while
near
record-high
values
observed
2020,
which
up
80%
above
mean.
Arctic,
highest
irradiances
record
measured
March
April
example
monthly
average
UVI
over
site
Canadian
Arctic
70%
higher
(2005-2019)
average,
often
this
mean
three
standard
deviations.
Under
presumption
all
countries
will
adhere
future
concentrations
remain
constant,
(30-60°)
projected
decrease
2015
2090
2-5%
north
4-6%
south
due
recovering
ozone.
for
tropics
are
≤
3%.
However,
industrial
regions
currently
affected
air
pollution,
increase
as
reduce
pollutants
gradually
restore
intensities
those
cleaner
atmosphere.
Since
most
substances
controlled
also
greenhouse
gases,
phase-out
these
may
avoided
warming
0.5-1.0
°C
mid-latitude
continents,
1.0
Arctic;
however,
uncertainty
calculations
large.
We
assess
climate,
focusing
poleward
shift
zones,
discuss
role
Antarctic
hole
2019
devastating
"Black
Summer"
fires
Australia.
Additional
topics
include
advances
measuring
modeling
radiation;
methods
determining
personal
exposure;
effect
management
(stratospheric
injections)
relevant
plants;
possible
revisions
vitamin
D
action
spectrum,
describes
wavelength
dependence
synthesis
previtamin
Photochemical & Photobiological Sciences,
Journal Year:
2023,
Volume and Issue:
22(5), P. 1049 - 1091
Published: Feb. 1, 2023
Terrestrial
organisms
and
ecosystems
are
being
exposed
to
new
rapidly
changing
combinations
of
solar
UV
radiation
other
environmental
factors
because
ongoing
changes
in
stratospheric
ozone
climate.
In
this
Quadrennial
Assessment,
we
examine
the
interactive
effects
ozone,
climate
on
terrestrial
biogeochemical
cycles
context
Montreal
Protocol.
We
specifically
assess
organisms,
agriculture
food
supply,
biodiversity,
ecosystem
services
feedbacks
system.
Emphasis
is
placed
role
extreme
events
altering
exposure
potential
biodiversity.
also
address
responses
plants
increased
temporal
variability
radiation,
change
(e.g.
drought,
temperature)
crops,
driving
breakdown
organic
matter
from
dead
plant
material
(i.e.
litter)
biocides
(pesticides
herbicides).
Our
assessment
indicates
that
interact
various
ways
affect
structure
function
ecosystems,
by
protecting
layer,
Protocol
continues
play
a
vital
maintaining
healthy,
diverse
land
sustain
life
Earth.
Furthermore,
its
Kigali
Amendment
mitigating
some
negative
consequences
limiting
emissions
greenhouse
gases
carbon
sequestration
vegetation
pool.
Scientific Reports,
Journal Year:
2019,
Volume and Issue:
9(1)
Published: Sept. 3, 2019
Abstract
The
Montreal
Protocol
on
Substances
that
Deplete
the
Ozone
Layer
has
been
hailed
as
most
successful
environmental
treaty
ever
(
https://www.unenvironment.org/news-and-stories/story/montreal-protocol-triumph-treaty
).
Yet,
although
our
main
concern
about
ozone
depletion
is
subsequent
increase
in
harmful
solar
UV
radiation
at
Earth’s
surface,
no
studies
to
date
have
demonstrated
its
effectiveness
regard.
Here
we
use
long-term
Index
(UVI)
data
derived
from
high-quality
spectroradiometer
measurements
demonstrate
success
curbing
increases
radiation.
Without
this
landmark
agreement,
UVI
values
would
increased
mid-latitude
locations
by
approximately
20%
between
early
1990s
and
today
quadruple
mid-latitudes
2100.
In
contrast,
an
analysis
of
multiple
clean-air
sites
shows
maximum
daily
remained
essentially
constant
over
last
~20
years
all
seasons,
may
even
decreased
slightly
southern
hemisphere,
especially
Antarctica,
where
effects
were
larger.
Reconstructions
total
show
evidence
increasing
levels
1980s,
but
unfortunately,
there
are
available
prior
confirm
these
with
direct
observations.
