Journal of Heterocyclic Chemistry,
Journal Year:
2024,
Volume and Issue:
61(7), P. 1045 - 1056
Published: May 8, 2024
Abstract
In
this
study,
a
highly
effective
microwave‐assisted
method
employing
multicomponent
domino
Knoevenagel/phospha‐Michael
reaction
has
been
established.
This
approach
facilitates
the
synthesis
of
novel
set
pyrazolylphosphonate
derivatives
in
good
yields
by
combining
aryl
aldehydes
with
pyrazolones
and
trialkylphosphites,
utilizing
piperidine
as
Bronsted
base
catalyst.
All
pyrazolylphosphonates
have
characterized
means
IR,
1
H‐NMR,
13
C‐NMR,
HRMS
analyses
physical
methods.
protocol
can
be
its
eco‐friendly
nature,
exceptional
efficiency
terms
product
yields,
short
times.
Applied Organometallic Chemistry,
Journal Year:
2021,
Volume and Issue:
35(9)
Published: June 22, 2021
Several
catalytic
reactions
such
as
Ullmann,
Chan–Lam,
Huisgen
1,3‐dipolar
cycloaddition,
[2
+
3]
condensation,
and
coupling
under
suitable
conditions
have
been
used
for
the
synthesis
of
fundamental
structures
containing
a
carbon–nitrogen
(C–N)
bond.
Graphene
oxide
(GO)
its
derivatives
heterogeneous
catalysts
attracted
considerable
attention
organic
building
blocks.
Loading
GO
with
copper
complexes
or
nanoparticles,
one
most
abundant
low
toxic
transition
metals,
allowed
to
design
new
composites
predominant
ability
C–N
bond
formation.
In
this
review
article,
we
present
comprehensive
overview
on
blocks
amines,
triazoles,
tetrazoles,
propargyl
imidazoles,
benzodiazepines
using
loaded
nanoparticles.
European Journal of Organic Chemistry,
Journal Year:
2022,
Volume and Issue:
2022(32)
Published: April 12, 2022
Abstract
A
C(5)−H
remote
functionalization
of
8‐aminoquinoline
derivatives
with
para
‐quinone
methides,
affording
direct
access
to
unsymmetrical
tri(hetero)arylmethanes
in
69–96
%
yield
is
described.
This
method
provides
diverse
a
broad
scope
and
regioselective
manner.
The
transformation
works
well
electron‐rich
electron‐deficient
substrates.
Organic & Biomolecular Chemistry,
Journal Year:
2022,
Volume and Issue:
20(34), P. 6831 - 6843
Published: Jan. 1, 2022
The
total
synthesis
of
antibacterial
amycolasporin
A,
(±)
amycolasporins
B
and
C
their
analogues
(18,
19,
30a
30d–30f)
was
introduced;
30d
obviously
inhibited
bacterial
biofilm
formation
promoted
intracellular
ROS
release.
Acta Crystallographica Section E Crystallographic Communications,
Journal Year:
2021,
Volume and Issue:
77(6), P. 663 - 667
Published: May 28, 2021
The
title
molecule,
C
29
H
N
3
O
4
S,
adopts
a
conformation
with
the
two
phenyl
substituents
disposed
on
opposite
sides
of
mean
plane
isoquinoline
unit.
In
crystal,
corrugated
layers
molecules
are
formed
by
N—H...O,
C—H...N
and
C—H...S
hydrogen
bonds
together
C—H...π(ring)
interactions.
These
connected
C—H...O
contacts.
Hirshfeld
surface
analysis
crystal
structure
indicates
that
most
important
contributions
for
packing
from
H...H
(45.2%),
C...H/H...C
(20.2%),
O...H/H...O
(15.8%)
N...H/H...N
(11.0%)
Journal of Heterocyclic Chemistry,
Journal Year:
2024,
Volume and Issue:
61(7), P. 1045 - 1056
Published: May 8, 2024
Abstract
In
this
study,
a
highly
effective
microwave‐assisted
method
employing
multicomponent
domino
Knoevenagel/phospha‐Michael
reaction
has
been
established.
This
approach
facilitates
the
synthesis
of
novel
set
pyrazolylphosphonate
derivatives
in
good
yields
by
combining
aryl
aldehydes
with
pyrazolones
and
trialkylphosphites,
utilizing
piperidine
as
Bronsted
base
catalyst.
All
pyrazolylphosphonates
have
characterized
means
IR,
1
H‐NMR,
13
C‐NMR,
HRMS
analyses
physical
methods.
protocol
can
be
its
eco‐friendly
nature,
exceptional
efficiency
terms
product
yields,
short
times.
