Magnetic Fluorescent Quantum Dots Nanocomposites in Food Contaminants Analysis: Current Challenges and Opportunities DOI Open Access
Jincheng Xiong, Huixia Zhang,

Linqian Qin

et al.

International Journal of Molecular Sciences, Journal Year: 2022, Volume and Issue: 23(8), P. 4088 - 4088

Published: April 7, 2022

The presence of food contaminants can cause foodborne illnesses, posing a severe threat to human health. Therefore, rapid, sensitive, and convenient method for monitoring is eagerly needed. complex matrix interferences samples poor performance existing sensing probes bring significant challenges improving detection performances. Nanocomposites with multifunctional features provide solution these problems. combination the superior characteristics magnetic nanoparticles (MNPs) quantum dots (QDs) fabricate fluorescent (MNPs@QDs) nanocomposites are regarded as an ideal probe analysis. high-efficiency pretreatment rapid fluorescence concurrently integrated into one platform using MNPs@QDs nanocomposites. In this review, contemporary synthetic strategies MNPs@QDs, including hetero-crystalline growth, template embedding, layer-by-layer assembly, microemulsion technique, one-pot method, described in detail, their advantages limitations discussed. recent advances detecting metal ions, pathogens, toxins, pesticides, antibiotics, illegal additives comprehensively introduced from perspectives modes review ends current opportunities practical applications prospects analysis, aiming promote enthusiasm research.

Language: Английский

Metal-organic frameworks-based nanozymes for combined cancer therapy DOI
Shuaishuai Ding, Ling He, Xiu‐Wu Bian

et al.

Nano Today, Journal Year: 2020, Volume and Issue: 35, P. 100920 - 100920

Published: Aug. 14, 2020

Language: Английский

Citations

122

Graphene and other 2D materials: a multidisciplinary analysis to uncover the hidden potential as cancer theranostics DOI Creative Commons
Laura Fusco, Arianna Gazzi, Guotao Peng

et al.

Theranostics, Journal Year: 2020, Volume and Issue: 10(12), P. 5435 - 5488

Published: Jan. 1, 2020

Cancer represents one of the main causes death in world; hence development more specific approaches for its diagnosis and treatment is urgently needed clinical practice. Here we aim at providing a comprehensive review on use 2-dimensional materials (2DMs) cancer theranostics. In particular, focus graphene-related (GRMs), graphene hybrids, graphdiyne (GDY), as well other emerging 2DMs, such MXene, tungsten disulfide (WS2), molybdenum (MoS2), hexagonal boron nitride (h-BN), black phosphorus (BP), silicene, antimonene (AM), germanene, biotite (black mica), metal organic frameworks (MOFs), others. The results reported scientific literature last ten years (>200 papers) are dissected here with respect to wide variety combinations imaging methodologies therapeutic approaches, including drug/gene delivery, photothermal/photodynamic therapy, sonodynamic immunotherapy. We provide unique multidisciplinary approach discussing literature, which also includes detailed section characterization methods used analyze material properties, highlighting merits limitations different approaches. this show strong potential 2DMs theranostics, highlight issues that prevent translation these materials. Overall, hope shed light hidden vast panorama new

Language: Английский

Citations

111

Dimeric prodrug-based nanomedicines for cancer therapy DOI

Shumeng Li,

Xinzhu Shan,

Yuequan Wang

et al.

Journal of Controlled Release, Journal Year: 2020, Volume and Issue: 326, P. 510 - 522

Published: July 25, 2020

Language: Английский

Citations

98

Multifunctional Prussian blue-based nanomaterials: Preparation, modification, and theranostic applications DOI
Xianwen Wang, Liang Cheng

Coordination Chemistry Reviews, Journal Year: 2020, Volume and Issue: 419, P. 213393 - 213393

Published: June 8, 2020

Language: Английский

Citations

96

Fascinating MXene nanomaterials: emerging opportunities in the biomedical field DOI
Xiangping Lin, Zhongjun Li,

Jinmei Qiu

et al.

Biomaterials Science, Journal Year: 2021, Volume and Issue: 9(16), P. 5437 - 5471

Published: Jan. 1, 2021

In recent years, there has been rapid progress in MXene research due to its distinctive two-dimensional structure and outstanding properties. Especially biomedical applications, MXenes have attracted widespread favor with numerous studies on biosafety, bioimaging, therapy, biosensing, although their development is still the experimental stage. A comprehensive understanding of current status biomedicine will promote use clinical applications. Here, we review advances research. First, introduce methods synthesis, surface modification functionalization MXenes. Then, summarize biosafety biocompatibility, paving way for specific On this basis, nanostructures are described respect antibacterial, cancer tissue regeneration biosensor Finally, discuss as a promising candidate material further applications biomedicine.

Language: Английский

Citations

92

Titanium-based nanomaterials for cancer theranostics DOI
Xianwen Wang, Xiaoyan Zhong, Liang Cheng

et al.

Coordination Chemistry Reviews, Journal Year: 2020, Volume and Issue: 430, P. 213662 - 213662

Published: Nov. 6, 2020

Language: Английский

Citations

91

Two-dimensional nanocoating-enabled orthopedic implants for bimodal therapeutic applications DOI
Song Wang, Chunyan Duan, Weizhong Yang

et al.

Nanoscale, Journal Year: 2020, Volume and Issue: 12(22), P. 11936 - 11946

Published: Jan. 1, 2020

A multifunctional two-dimensional nanocoating consists of graphene oxide nanosheets, polydopamine nanofilm, and oligopeptide constructed on porous sulfonated polyetheretherketone for the purpose bone infection treatment.

Language: Английский

Citations

81

Recent Development of Photothermal Agents (PTAs) Based on Small Organic Molecular Dyes DOI

Shibo Lv,

Yuyang Miao, Dapeng Liu

et al.

ChemBioChem, Journal Year: 2020, Volume and Issue: 21(15), P. 2098 - 2110

Published: March 23, 2020

Photothermal therapy (PTT) has attracted great attention due to its noninvasive and effective use against cancer. Various photothermal agents (PTAs) including organic inorganic PTAs have been developed in the last decades. Organic based on small-molecule dyes exhibit potential for future clinical applications considering their good biocompatibility easy chemical modification or functionalization. In this review, we discuss recent progress of enhanced PTT. We summarize strategies improve light penetration PTAs, methods enhance conversion efficiency, how optimize PTAs' delivery into deep tumors, resist photobleaching under repeated laser irradiation. hope that review can rouse interest researchers field help them fabricate next-generation cancer therapy.

Language: Английский

Citations

73

Specific Forms of Graphene Quantum Dots Induce Apoptosis and Cell Cycle Arrest in Breast Cancer Cells DOI Open Access

Tien-Hsiung Ku,

Wenting Shen,

Chien‐Te Hsieh

et al.

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(4), P. 4046 - 4046

Published: Feb. 17, 2023

Graphene quantum dots (GQDs), nanomaterials derived from graphene and carbon dots, are highly stable, soluble, have exceptional optical properties. Further, they low toxicity excellent vehicles for carrying drugs or fluorescein dyes. Specific forms of GQDs can induce apoptosis could be used to treat cancers. In this study, three (GQD (nitrogen:carbon = 1:3), ortho-GQD, meta-GQD) were screened tested their potential inhibit breast cancer cell (MCF-7, BT-474, MDA-MB-231, T-47D) growth. All decreased viability after 72 h treatment specifically affected proliferation. An assay the expression apoptotic proteins revealed that p21 p27 up-regulated (1.41-fold 4.75-fold) treatment. particular, ortho-GQD-treated cells showed G2/M phase arrest. The induced in estrogen receptor-positive lines. These results indicate these cycle arrest specific subtypes potentially treating

Language: Английский

Citations

27

Biodegradable CoS2 nanoclusters for photothermal-enhanced chemodynamic therapy DOI
Xianwen Wang, Xiaoyan Zhong, Zhengbao Zha

et al.

Applied Materials Today, Journal Year: 2019, Volume and Issue: 18, P. 100464 - 100464

Published: Nov. 3, 2019

Language: Английский

Citations

68