Diastereoselective construction of structurally diverse trifluoromethyl bispiro-[oxindole-pyrrolidine-chromanone]s through [3+2] cycloaddition reactions DOI
Zheng Li, Lu Yu,

You‐Ping Tian

et al.

Tetrahedron, Journal Year: 2021, Volume and Issue: 98, P. 132297 - 132297

Published: June 18, 2021

Language: Английский

Synthesis of Cyclohexenone(aryl)iodonium Salts and Their Application in Construction of Fused aza‐Heterocyclic Skeletons DOI
Shuoshuo Zhang,

Lingzhi Xu,

Xuemin Li

et al.

Advanced Synthesis & Catalysis, Journal Year: 2024, Volume and Issue: 366(21), P. 4462 - 4469

Published: July 23, 2024

Abstract A class of cyclohexenone(aryl)iodonium salts was readily prepared from 2‐iodocyclohexenones and arenes under mild conditions. This novel series hypervalent iodonium building blocks exhibits dual characteristics hyperiodonium α,β‐unsaturated cyclic ketones, enabling access to intricate aza‐heterocycles. The reaction these with arylamines or aryl sulfonamides affords 2‐acylaziridines, while 2‐aminobenzimidazoles 2‐aminoimidazoles leads the formation 1 H ‐imidazo[1,2‐ a ]imidazole‐fused compounds. transformation is postulated proceed through an exclusive hyperiodonium‐mediated N ‐Michael addition followed by ‐annulation cascade.

Language: Английский

Citations

1
Advanced glycation end-products (AGE) trapping agents: Design and synthesis of nature inspired indeno[2,1-c]pyridinones DOI
Anaga Nair,

D Basavaraja,

Billu Abraham

et al.

Bioorganic Chemistry, Journal Year: 2020, Volume and Issue: 105, P. 104375 - 104375

Published: Oct. 13, 2020

Language: Английский

Citations

11
Palladium-catalyzed directing group assisted and regioselectivity reversed cyclocarbonylation of arylallenes with 2-iodoanilines DOI
Jian‐Shu Wang, Lingyun Yao, Jun Ying

et al.

Organic Chemistry Frontiers, Journal Year: 2020, Volume and Issue: 8(4), P. 792 - 798

Published: Dec. 8, 2020

A palladium-catalyzed regioselective cyclocarbonylation ofN-(2-pyridyl)sulfonyl (N-SO2Py)-2-iodoanilines with allenes was developed. The regioselectivity of arylallenes reversed. Control experiments and DFT calculations were performed to understand the reaction details.

Language: Английский

Citations

9
3‐Arylidene‐4‐Chromanones and 3‐Arylidene‐4‐Thiochromanones: Versatile Synthons towards the Synthesis of Complex Heterocycles DOI
Ayisha F. Begum, K. K. Balasubramanian, Bhagavathy Shanmugasundaram

et al.

Asian Journal of Organic Chemistry, Journal Year: 2022, Volume and Issue: 11(10)

Published: Aug. 16, 2022

Abstract Heterocyclic compounds are well‐known for their use in the synthesis of drugs and drug intermediates. This review provides a systematic survey on chemical complex heterocyclic containing multi‐stereocentres using 3‐arylidene‐4‐chromanones last two decades. Regioselective stereoselective heterocycles involving 3‐arylidene‐chromanones 3‐arylidene‐thiochormanones dealt under various reaction headings such as epoxidation, Michael addition, 1,3‐dipolar cycloaddition, [3+2] [4+2] Diels‐Alder reaction, sulfa‐Michael/aldol cascade reactions, asymmetric employing bifunctional catalysts, chiral phase‐transfer squaramide etc . These synthetic highlights demonstrate utility versatile synthons rapid assemblage condensed heterocyles spiro ‐fused towards development pharmaceutically active compounds. A brief highlight methods 3‐arylidene‐4‐chromanone derivatives is also dealt. creates platform further improvement skeletal design potential candidates.

Language: Английский

Citations

6
A Synthetic Overview of Enones Aziridination DOI
Dinesh Chandra,

Puneet Kumar,

Ajay Yadav

et al.

ChemistrySelect, Journal Year: 2022, Volume and Issue: 7(22)

Published: June 9, 2022

Abstract Aziridines are an important class of synthetic intermediates that widely used in the synthesis useful compounds and found pharmaceuticals, natural products, other functional materials. Several with aziridine ring system exhibit significant biological activity as well. Consequently, aziridines has been focus intense research over last two decades. Despite numerous successful methods, no review article exclusively on Enone aziridination published to date. Therefore, up‐to‐date developments from enones, which convenient precursors, by nucleophilic addition reactions described advantages, limitations, mechanistic pathways.

Language: Английский

Citations

5
Ethylbenzene Hydroperoxide: An efficient oxidizing agent for diastereoselective synthesis of Spiroepoxy oxindoles DOI

Praveen K. Valmiki,

Mohan Banyangala,

Sunil Varughese

et al.

Tetrahedron Letters, Journal Year: 2022, Volume and Issue: 108, P. 154126 - 154126

Published: Sept. 5, 2022

Language: Английский

Citations

5
Diastereoselective construction of structurally diverse trifluoromethyl bispiro-[oxindole-pyrrolidine-chromanone]s through [3+2] cycloaddition reactions DOI
Zheng Li, Lu Yu,

You‐Ping Tian

et al.

Tetrahedron, Journal Year: 2021, Volume and Issue: 98, P. 132297 - 132297

Published: June 18, 2021

Language: Английский

Citations

4