Additively manufactured functionally graded biodegradable porous zinc DOI Creative Commons
Yageng Li,

P. Pavanram,

Jie Zhou

et al.

Biomaterials Science, Journal Year: 2020, Volume and Issue: 8(9), P. 2404 - 2419

Published: Jan. 1, 2020

First report on the effect of topology design biodegradation, mechanical properties, and cell responses additively manufactured Zn.

Language: Английский

Additive manufacturing of metallic lattice structures: Unconstrained design, accurate fabrication, fascinated performances, and challenges DOI
Liang‐Yu Chen, Shun‐Xing Liang, Yujing Liu

et al.

Materials Science and Engineering R Reports, Journal Year: 2021, Volume and Issue: 146, P. 100648 - 100648

Published: Oct. 1, 2021

Language: Английский

Citations

390

Design and Optimization of Lattice Structures: A Review DOI Creative Commons
Chen Pan, Yafeng Han,

Jiping Lu

et al.

Applied Sciences, Journal Year: 2020, Volume and Issue: 10(18), P. 6374 - 6374

Published: Sept. 13, 2020

Cellular structures consist of foams, honeycombs, and lattices. Lattices have many outstanding properties over foams such as lightweight, high strength, absorbing energy, reducing vibration, which has been extensively studied concerned. Because excellent properties, lattice widely used in aviation, bio-engineering, automation, other industrial fields. In particular, the application additive manufacturing (AM) technology for fabricating pushed development designing to a new stage made breakthrough progress. By searching large number research literature, primary work this paper reviews structures. First, based on introductions about lattices definition classification are concluded. Lattice divided into two general categories paper: uniform non-uniform. Second, performance introduced detail. addition, methods structures, i.e., traditional processing manufacturing, evaluated. Third, main concern during design is develop highly functional unit cells, summarized three different methods, geometric cell based, mathematical algorithm generated, topology optimization. Forth, non-uniform reviewed from aspects gradient These include Voronoi-tessellation, size method (SGM), matching scaling (SMS), homogenization, optimization, construction (HOC). Finally, future prospected aspects.

Language: Английский

Citations

383

Substrate curvature as a cue to guide spatiotemporal cell and tissue organization DOI Creative Commons
Sebastien J. P. Callens,

Rafael J.C. Uyttendaele,

Lidy E. Fratila‐Apachitei

et al.

Biomaterials, Journal Year: 2019, Volume and Issue: 232, P. 119739 - 119739

Published: Dec. 27, 2019

Recent evidence clearly shows that cells respond to various physical cues in their environments, guiding many cellular processes and tissue morphogenesis, pathology, repair. One aspect is gaining significant traction the role of local geometry as an extracellular cue. Elucidating how affects cell behavior is, indeed, crucial design artificial scaffolds understand growth remodeling. Perhaps most fundamental descriptor surface curvature, a growing body confirms curvature spatiotemporal organization tissues. While well-defined differential geometry, remains somewhat ambiguously treated biological studies. Here, we provide more formal framework, based on notions mean Gaussian summarize available guidance at levels. We discuss involved mechanisms, highlighting interplay between tensile forces substrate forms foundation guidance. Moreover, show relatively simple computational models, some application flow, are able capture experimental remarkably well. Since principles could be leveraged for regeneration, implications geometrical scaffold also discussed. Finally, perspectives future research opportunities provided.

Language: Английский

Citations

269

Additively manufactured biodegradable porous iron DOI
Yageng Li, Holger Jahr,

Karel Lietaert

et al.

Acta Biomaterialia, Journal Year: 2018, Volume and Issue: 77, P. 380 - 393

Published: July 6, 2018

Language: Английский

Citations

251

Reversible energy absorbing meta-sandwiches by FDM 4D printing DOI
Mahdi Bodaghi, Ahmad Serjouei, Ali Zolfagharian

et al.

International Journal of Mechanical Sciences, Journal Year: 2020, Volume and Issue: 173, P. 105451 - 105451

Published: Jan. 15, 2020

Language: Английский

Citations

210

Multi-material additive manufacturing technologies for Ti-, Mg-, and Fe-based biomaterials for bone substitution DOI Creative Commons
N.E. Putra, Mohammad J. Mirzaali, I. Apachitei

et al.

Acta Biomaterialia, Journal Year: 2020, Volume and Issue: 109, P. 1 - 20

Published: April 6, 2020

The growing interest in multi-functional metallic biomaterials for bone substitutes challenges the current additive manufacturing (AM, =3D printing) technologies. It is foreseeable that advances multi-material AM will not only allow complex geometrical designs, but also improve their multi-functionalities by tuning types or compositions of underlying base materials, thereby presenting unprecedented opportunities advanced orthopedic treatments. technologies are yet to be extensively explored fabrication biomaterials, especially substitutes. aim this review present viable options state-of-the-art Ti-, Mg-, and Fe-based used as starts with a brief tissue engineering, design requirements, highlight advantages using over conventional methods. Five suitable metal 3D printing compared against requirements AM. Of these technologies, extrusion-based shown have greatest potential meet biomaterials. Finally, recent progress including utilization reviewed so identify knowledge gaps propose directions further research development applicable Addressing critical defect requires assistance porous As one most technology challenged its viability This article reviews how been can Progress on manufacturing, discussed direct future advancing additively manufactured

Language: Английский

Citations

178

Additively manufactured biodegradable porous metals DOI Creative Commons
Yageng Li, Holger Jahr, Jie Zhou

et al.

Acta Biomaterialia, Journal Year: 2020, Volume and Issue: 115, P. 29 - 50

Published: Aug. 24, 2020

Partially due to the unavailability of ideal bone substitutes, treatment large bony defects remains one most important challenges orthopedic surgery. Additively manufactured (AM) biodegradable porous metals that have emerged since 2018 provide unprecedented opportunities for fulfilling requirements an implant. First, multi-scale geometry these implants can be customized mimic human in terms both micro-architecture and mechanical properties. Second, a structure with interconnected pores possesses surface area, which is favorable adhesion proliferation cells and, thus, ingrowth. Finally, freeform geometrical design such biomaterials could exploited adjust their biodegradation behavior so as maintain structural integrity implant during healing process while ensuring disappears afterwards, paving way full regeneration. While AM been studied far shown many unique properties compared solid counterparts, degree flexibility has not yet fully optimize performance. In order develop implants, it take advantage potential through detailed systematic study on behavior, properties, biocompatibility, regeneration This review paper presents state art focused effects material type, processing, design, post-AM treatments vitro vivo performance Mg, Fe, Zn well alloys. We also identify number knowledge gaps encountered adopting applications suggest some promising areas future research.

Language: Английский

Citations

158

Additively manufactured metallic biomaterials DOI Creative Commons
Elham Davoodi, Hossein Montazerian,

Anooshe Sadat Mirhakimi

et al.

Bioactive Materials, Journal Year: 2021, Volume and Issue: 15, P. 214 - 249

Published: Dec. 30, 2021

Metal additive manufacturing (AM) has led to an evolution in the design and fabrication of hard tissue substitutes, enabling personalized implants address each patient's specific needs. In addition, internal pore architectures integrated within additively manufactured scaffolds, have provided opportunity further develop engineer functional for better integration, long-term durability. this review, latest advances different aspects metallic biomaterials are highlighted. After introducing metal AM processes, biocompatible metals adapted integration with machines presented. Then, we elaborate on tools approaches undertaken porous scaffold engineered architecture including, topology optimization techniques, as well unit cell patterns based lattice networks, triply periodic minimal surface. Here, new possibilities brought by functionally gradient structures meet conflicting requirements thoroughly discussed. Subsequently, constraints physical characteristics constructs reviewed terms input parameters such features processing parameters. We assess proposed applications regeneration types efforts made towards their clinical translation. Finally, conclude review emerging directions perspectives development medical industry.

Language: Английский

Citations

153

High performance, microarchitected, compact heat exchanger enabled by 3D printing DOI Creative Commons
Tisha Dixit, Ebrahim Al-Hajri, Manosh C. Paul

et al.

Applied Thermal Engineering, Journal Year: 2022, Volume and Issue: 210, P. 118339 - 118339

Published: March 18, 2022

Additive manufacturing has created a paradigm shift in materials design and innovation, providing avenues opportunities for geometric freedom customizations. Here, we report microarchitected gyroid lattice liquid–liquid compact heat exchanger realized via stereolithography additive as single ready-to-use unit. This lightweight (∼240 kg/m3) (with conjoined headers), with an engineered porosity of 80% separating wall thickness 300 μm, surface to volume ratio 670 m2/m3. X-ray computed tomography imaging confirms defect-free 3D printed exchanger. The thermo-hydraulic characteristics were experimentally measured using water the working fluid. measurements indicate that evinces overall transfer coefficient 120-160W/m2K hot fluid Reynolds number Reh range 10-40. Additionally, finite element analysis was conducted evaluate experimental results show -a 55% increase effectiveness additively manufactured comparison thermodynamically equivalent, most-efficient, counter-flow at one tenth its size. superiority our architected extant work is also demonstrated.

Language: Английский

Citations

143

3D printing metal implants in orthopedic surgery: Methods, applications and future prospects DOI Creative Commons
Meng Meng, Jinzuo Wang,

Huagui Huang

et al.

Journal of Orthopaedic Translation, Journal Year: 2023, Volume and Issue: 42, P. 94 - 112

Published: Sept. 1, 2023

Currently, metal implants are widely used in orthopedic surgeries, including fracture fixation, spinal fusion, joint replacement, and bone tumor defect repair. However, conventional difficult to be customized according the recipient's skeletal anatomy characteristics, leading difficulties meeting individual needs of patients. Additive manufacturing (AM) or three-dimensional (3D) printing technology, an advanced digital fabrication technique capable producing components with complex precise structures, offers opportunities for personalization. We systematically reviewed literature on 3D over past 10 years. Relevant animal, cellular, clinical studies were searched PubMed Web Science. In this paper, we introduce method characteristics biometals summarize properties their applications surgery. On basis, discuss potential possibilities further generalization improvement. technology has facilitated use different procedures. By combining medical images from techniques such as CT MRI, allows based injured tissue. Such patient-specific not only reduce excessive mechanical strength eliminate stress-shielding effects, but also improve biocompatibility functionality, increase cell nutrient permeability, promote angiogenesis growth. addition, advantages low cost, fast cycles, high reproducibility, which can shorten patients' surgery hospitalization time. Many trials have been conducted using implants. modeling software, operation equipment, demand implant materials, lack guidance relevant laws regulations limited its application. There personalization, promotion osseointegration, short production cycle, material utilization. With continuous learning software by surgeons, improvement development materials that better meet needs, regulations, applied more surgeries. Precision, intelligence, personalization future direction orthopedics. It is reasonable believe will deeply integrated artificial 4D printing, big data play a greater role eventually become important part economy. aim latest developments engineers surgeons design closely mimic morphology function native bone.

Language: Английский

Citations

100