Chinese Journal of Organic Chemistry, Journal Year: 2022, Volume and Issue: 42(9), P. 2867 - 2867
Published: Jan. 1, 2022
Language: Английский
Chinese Journal of Organic Chemistry, Journal Year: 2022, Volume and Issue: 42(9), P. 2867 - 2867
Published: Jan. 1, 2022
Language: Английский
Organic Letters, Journal Year: 2022, Volume and Issue: 24(43), P. 7912 - 7917
Published: Oct. 21, 2022
3-(2-(Ethynyl)phenyl)quinazolinones were designed and synthesized as a class of novel efficient skeletons for phosphorylation/cyclization reactions. Under visible light irradiation, series phosphorylated quinolino[2,1-b]quinazolinones (35 examples, up to 87% yield) first from 3-(2-(ethynyl)phenyl)quinazolinones diarylphosphine oxides by using 4CzIPN photocatalyst under mild conditions. This reaction was also applicable sunlight irradiation. Moreover, the efficiency could be significantly improved continuous-flow
Language: Английский
Citations
27The Journal of Organic Chemistry, Journal Year: 2023, Volume and Issue: 88(18), P. 13279 - 13290
Published: Aug. 31, 2023
A strategy utilizing silver-catalyzed oxidative decarboxylation radical cascade cyclization of arylthiodifluoroacetic acids with alkenes for the simple and efficient preparation difluoromethylated thiochromanes 2,2-disubstituted-N-arylbutanamides derivatives has been developed. This approach includes good functional group tolerance, easily accessible starting materials, operational simplicity.
Language: Английский
Citations
16Organic Chemistry Frontiers, Journal Year: 2023, Volume and Issue: 10(13), P. 3252 - 3258
Published: Jan. 1, 2023
A novel one-pot method for synthesizing polysubstituted pyrrole derivatives via three-component reactions of alkenyl bromides, amines, and isocyanides is reported by Pd catalysis, without additional ligands, with the orderly insertion three isocyanide molecules.
Language: Английский
Citations
12Organic Letters, Journal Year: 2022, Volume and Issue: 24(3), P. 859 - 863
Published: Jan. 12, 2022
Herein a novel and concise approach to pyrrole skeletons via Pd-catalyzed tandem cyclization reactions is investigated. The substrates for the transformation could be readily prepared by phosphoric acid-catalyzed Ugi with available starting materials. In this strategy, two isocyanides participate in sequential isocyanide insertion reactions, chemoselectivity of products regulated steric hindrance isocyanide. A plausible mechanism formation corresponding adducts proposed.
Language: Английский
Citations
19The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(18), P. 13457 - 13471
Published: Sept. 3, 2024
Organic molecules containing a difluoroalkyl group are valuable and versatile chemicals because of their unique physicochemical biological properties. Accordingly, the development efficient practical difluoroalkylation for preparation these compounds is important attractive. Herein, we demonstrate photoredox-catalyzed base-dependent selective carbodifluoroalkylation halodifluoroalkylation alkenes using readily available 2-(allyloxy)arylaldehydes [or 2-(allylamino)arylaldehydes] XCF
Language: Английский
Citations
3Organic & Biomolecular Chemistry, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
A photochemical radical cascade cyclization reaction of isocyanides with α-carbonyl bromides under mild conditions is disclosed for accessing 1,4-dibenzodiazepines, demonstrating good tolerance towards various functional groups.
Language: Английский
Citations
0Green Synthesis and Catalysis, Journal Year: 2025, Volume and Issue: unknown
Published: April 1, 2025
Language: Английский
Citations
0Green Synthesis and Catalysis, Journal Year: 2025, Volume and Issue: unknown
Published: April 1, 2025
Language: Английский
Citations
0The Journal of Organic Chemistry, Journal Year: 2022, Volume and Issue: 88(1), P. 198 - 210
Published: Dec. 22, 2022
A Mn(III)-mediated radical addition/cyclization reaction of isocyanides with aryl boronic acids/diarylphosphine oxides has been developed. series 11-arylated/-phosphorylated dibenzodiazepines were efficiently constructed in moderate to excellent yields under mild conditions via imidoyl process. The present protocol offers novel access functionalized seven-membered N-heterocycles.
Language: Английский
Citations
14Organic Letters, Journal Year: 2022, Volume and Issue: 24(8), P. 1668 - 1672
Published: Feb. 22, 2022
A green, sustainable, and straightforward method for the synthesis of unsymmetrical oxalamides via photoinduced C–N/C═O bond formation bromodifluoroacetamide, amine, H2O through a triple-cleavage process has been developed. In addition, this approach also provides access to known bioactive compounds, feasible reaction mechanism is proposed. Moreover, advantages transformation, including mild conditions, broad substrate scope, operational simplicity, make protocol attractive further applications.
Language: Английский
Citations
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