Asian Journal of Organic Chemistry,
Journal Year:
2022,
Volume and Issue:
11(2)
Published: Jan. 21, 2022
Abstract
An
efficient
iron‐catalyzed
allylation
of
cycloalkyl
hydroperoxides
with
allylic
sulfones
via
C−C
bond
cleavage
is
presented.
This
protocol
provides
an
approach
to
a
wide
range
distally
allylated
ketones
good
functional
group
tolerance
and
high
regioselectivity
under
redox‐neutral
conditions.
Preliminary
mechanistic
study
implies
radical
process
might
be
involved
in
this
reaction.
Chemical Society Reviews,
Journal Year:
2024,
Volume and Issue:
53(5), P. 2326 - 2349
Published: Jan. 1, 2024
This
review
summarizes
the
advances
in
metal-catalyzed
asymmetric
reactions
enabled
by
organic
peroxides
that
have
been
found
to
exhibit
multifunctionalities,
for
instance,
applied
as
stoichiometric
reactants,
reagents,
or
catalytic
amount
reagents.
Journal of the American Chemical Society,
Journal Year:
2023,
Volume and Issue:
145(32), P. 17527 - 17550
Published: Aug. 2, 2023
The
C–O
bond
is
ubiquitous
in
biologically
active
molecules,
pharmaceutical
agents,
and
functional
materials,
thereby
making
it
an
important
group.
Consequently,
the
development
of
bond-forming
reactions
using
catalytic
strategies
has
become
increasingly
research
topic
organic
synthesis
because
more
conventional
methods
involving
strong
base
acid
have
many
limitations.
In
contrast
to
ionic-pathway-based
methods,
copper-promoted
radical-mediated
formation
experiencing
a
surge
interest
owing
renaissance
free-radical
chemistry
photoredox
catalysis.
This
Perspective
highlights
appraises
state-of-the-art
techniques
this
burgeoning
field.
contents
are
organized
according
different
reaction
types
working
models.
Trends in Chemistry,
Journal Year:
2023,
Volume and Issue:
5(3), P. 174 - 200
Published: Feb. 14, 2023
Organic
peroxides
are
becoming
popular
intermediates
for
novel
chemical
transformations.
The
weak
O-O
bond
is
readily
reduced
by
transition
metals,
including
iron
and
copper,
to
initiate
a
radical
cascade
process
that
breaks
C-C
bonds.
Great
potential
exists
the
rapid
generation
of
complexity,
originating
from
ability
couple
resulting
free
radicals
with
wide
range
partners.
First,
this
review
article
discusses
history
synthesis
organic
peroxides,
providing
context
necessary
understand
methodology.
Then,
it
highlights
91
examples
recent
applications
functionalization
bonds
accessed
through
metal-mediated
reduction
peroxides.
Finally,
we
provide
some
comments
about
safety
when
working
Chemical Science,
Journal Year:
2024,
Volume and Issue:
15(13), P. 4757 - 4762
Published: Jan. 1, 2024
α-Keto-,
β-acetoxy-
and
β-amidoalkylsilyl
peroxides
are
prepared
from
various
precursors
utilized
for
Fe-catalyzed
visible-light-promoted
radical
functionalization
with
coupling
partners
under
mild
conditions
a
broad
substrate
scope.
Chemical Communications,
Journal Year:
2023,
Volume and Issue:
59(88), P. 13175 - 13178
Published: Jan. 1, 2023
An
NHC
organocatalytic
radical
acylation
of
cycloalkyl
silyl
peroxides
with
aldehydes
was
developed
for
the
efficient
and
rapid
synthesis
long-chain
1,6-/1,7-/1,8-diketones,
especially
unsymmetrical
ones.
Chemical Communications,
Journal Year:
2021,
Volume and Issue:
57(69), P. 8652 - 8655
Published: Jan. 1, 2021
An
efficient
copper-catalyzed
radical
ring-opening
halogenation
with
HX
(aq)
is
described.
This
protocol
provides
a
practical
access
to
distally
chlorinated,
brominated
and
iodinated
alkyl
ketones
nitriles
moderate
good
yields.
The Journal of Organic Chemistry,
Journal Year:
2021,
Volume and Issue:
86(17), P. 11987 - 11997
Published: Aug. 10, 2021
A
cheap
iron-catalyzed
C–C
bond
cleavage/thiolation
and
selenylation
of
cycloalkyl
hydroperoxides
are
presented.
This
redox-neutral
protocol
provides
efficient
access
to
diverse
distal
keto-functionalized
thioethers
selenium
compounds.
Remarkably,
only
some
amounts
disulfides
required
for
this
transformation.
