Aggregation-Induced Emission (AIE), Life and Health

ACS Nano, Journal Year: 2023, Volume and Issue: 17(15), P. 14347 - 14405

Published: July 24, 2023

Light has profoundly impacted modern medicine and healthcare, with numerous luminescent agents imaging techniques currently being used to assess health treat diseases. As an emerging concept in luminescence, aggregation-induced emission (AIE) shown great potential biological applications due its advantages terms of brightness, biocompatibility, photostability, positive correlation concentration. This review provides a comprehensive summary AIE luminogens applied structure dynamic physiological processes, disease diagnosis treatment, detection monitoring specific analytes, followed by representative works. Discussions on critical issues perspectives future directions are also included. aims stimulate the interest researchers from different fields, including chemistry, biology, materials science, medicine, etc., thus promoting development fields life health.

Language: Английский

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Clustering and halogen effects enabled red/near-infrared room temperature phosphorescence from aliphatic cyclic imides

Nature Communications, Journal Year: 2022, Volume and Issue: 13(1)

Published: May 12, 2022

Abstract Pure organic room temperature phosphorescence (RTP) materials become increasingly important in advanced optoelectronic and bioelectronic applications. Current phosphors based on small aromatic molecules show emission characteristics generally limited to short wavelengths. It remains an enormous challenge achieve red near-infrared (NIR) RTP, particularly for those from nonaromatics. Here we demonstrate that succinimide derived cyclic imides can emit RTP the (665, 690 nm) NIR (745 spectral range with high efficiencies of up 9.2%. Despite their rather molecular conjugations, unique stems presence imide unit heavy atoms, effective clustering, electron delocalization halogens. We further atoms like halogen or chalcogen these systems is facilitate intersystem crossing as well extend through-space conjugation enable rigidified conformations. This universal strategy paves way design nonconventional luminophores long wavelength emerging

Language: Английский

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Altering Chain Flexibility of Aliphatic Polyesters for Yellow‐Green Clusteroluminescence in 38 % Quantum Yield

Angewandte Chemie International Edition, Journal Year: 2021, Volume and Issue: 61(6)

Published: Nov. 25, 2021

Preparation of non-conjugated polymers with long-wavelength emission and high quantum yield (QY) is still a huge challenge. Herein, we report the first example linear polyester exhibiting yellow-green clusteroluminescence (CL) QY 38 %. We discovered that P3 balanced flexibility rigidity showed longest CL wavelength highest QY. Systematically photophysical characterization unravel key role ester cluster in formation via aggregate units was visualized. Moreover, demonstrated to be highly selective, quick-responsive (ca. 1.2 min) sensitive detector (detection limit 0.78 μM) for irons owing fast disassociation clusters by irons. This work not only gains further mechanistic insight into but also provides new strategy design high-efficiency CL, meanwhile, enlightens glorious application prospect luminescent polyester.

Language: Английский

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Clusterization-Triggered Color-Tunable Room-Temperature Phosphorescence from 1,4-Dihydropyridine-Based Polymers

Journal of the American Chemical Society, Journal Year: 2021, Volume and Issue: 144(3), P. 1361 - 1369

Published: Dec. 23, 2021

A series of poly(1,4-dihydropyridine)s (PDHPs) were successfully synthesized via one-pot metal-free multicomponent polymerization diacetylenic esters, benzaldehyde, and aniline derivatives. These PDHPs without traditional luminescent units endowed with tunable triplet energy levels by through-space conjugation from the formation different cluster sizes. The large compact clusters can effectively extend phosphorescence wavelength. excitons be stabilized using benzophenone as a rigid matrix to achieve room-temperature phosphorescence. nonconjugated polymeric show emission up 645 nm. combination static dynamic laser light scattering was conducted for insight into structural information on formed in host melt. Moreover, both fluorescence easily tuned variation excitation wavelength, concentration, molecular weight guest polymers. This work provides unique designing host-guest systems new strategy development long wavelength materials.

Language: Английский

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Hyperbranched Polyborate: A Non‐conjugated Fluorescent Polymer with Unanticipated High Quantum Yield and Multicolor Emission

Angewandte Chemie International Edition, Journal Year: 2022, Volume and Issue: 61(29)

Published: May 2, 2022

Abstract Non‐conjugated fluorescent polymers have attracted great attention due to their excellent biocompatibility and environmental friendliness. However, it remains a huge challenge obtain polymer with high fluorescence quantum yield (QY) multicolor emission simultaneously. Herein, we reported three kinds of nonaromatic hyperbranched polyborates ( P1 – P3 ) emission, surprisingly, P2 also exhibits an unanticipated QY (54.1 %). The natural bond orbital (NBO) analysis density functional theory (DFT) calculation results revealed that the synergistic effect rigid BO 3 planar flexible carbon chain, as well through‐space dative in supramolecular aggregate, were key factors contributing ultrahigh . Moreover, applications Fe 3+ ions detection cell imaging investigated. This work provides new perspective for designing non‐conjugated both emission.

Language: Английский

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Secondary through-space interactions facilitated single-molecule white-light emission from clusteroluminogens

Nature Communications, Journal Year: 2022, Volume and Issue: 13(1)

Published: June 17, 2022

Clusteroluminogens refer to some non-conjugated molecules that show visible light and unique electronic properties with through-space interactions due the formation of aggregates. Although mature systematic theories molecular photophysics have been developed study conventional conjugated chromophores, it is still challenging endow clusteroluminogens designed photophysical by manipulating interactions. Herein, three donor-acceptor structures different halide substituents are synthesized. These compounds multiple emissions even single-molecule white-light emission in crystalline state. The intensity ratio these easily manipulated changing atom excitation wavelength. Experimental theoretical results successfully disclose nature emissions: conjugation for short-wavelength fluorescence, charge transfer based on secondary long-wavelength room-temperature phosphorescence. introduction not only enriches their varieties but also inspires establishment novel aggregate clusteroluminescence.

Language: Английский

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Highly efficient and persistent room temperature phosphorescence from cluster exciton enables ultrasensitive off-on VOC sensing

Matter, Journal Year: 2022, Volume and Issue: 5(10), P. 3499 - 3512

Published: July 30, 2022

Language: Английский

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Accessing Excitation‐ and Time‐Responsive Afterglows from Aqueous Processable Amorphous Polymer Films through Doping and Energy Transfer

Advanced Materials, Journal Year: 2022, Volume and Issue: 34(31)

Published: June 10, 2022

Abstract Smart afterglow materials in response to excitation and delay time, including crystals, polymeric films, carbon dots, have attracted considerable attention on account of their fundamental value photophysics promising applications optoelectronics. However, the fabrication amorphous flexible polymer films with fine control remains underexplored. Herein, new doped based sodium alginate aromatic carboxylates are developed, which demonstrate following advantages: (i) easy fast through aqueous solution process, (ii) flexible, transparent, re‐dissolvable characteristics, (iii) multi‐tunable colors from blue red even white control. Specifically, better controllability can be achieved co‐doping triplet‐to‐singlet Förster resonance energy transfer (TS‐FRET). Multimode advanced anti‐counterfeiting these is demonstrated using excitation‐ time‐dependent as well TS‐FRET‐mediated colors.

Language: Английский

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Excited-State Intramolecular Proton Transfer Dyes with Dual-State Emission Properties: Concept, Examples and Applications

Molecules, Journal Year: 2022, Volume and Issue: 27(8), P. 2443 - 2443

Published: April 10, 2022

Dual-state emissive (DSE) fluorophores are organic dyes displaying fluorescence emission both in dilute and concentrated solution the solid-state, as amorphous, single crystal, polycrystalline samples or thin films. This comes contrast to vast majority of fluorescent which typically show intense but quenched media solid-state owing π-stacking interactions; a well-known phenomenon called aggregation-caused quenching (ACQ). On contrary, molecular rotors with significant number free rotations have been engineered strong aggregated-state thanks restriction intramolecular motions. is concept aggregation-induced (AIE). DSE far less explored despite fact that they at crossroad ACQ AIE phenomena allow targeting applications (bio-conjugation, sensing, imaging) (organic electronics, data encryption, lasing, luminescent displays). Excited-State Intramolecular Proton Transfer (ESIPT) particularly suitable engineer dyes. Indeed, ESIPT fluorescence, relies on phototautomerism between normal tautomeric species, characterized by along large Stokes’ shift, an enhanced photostability sensitivity close environment, feature prone be used bio-sensing. A drawback needs overcome their weak intensity solution, detrimental motions excited-state. Several strategies proposed regard. In past few years, growing examples DSE-ESIPT indeed emerged literature, enriching database such attractive review aims brief concise overview exploitation luminescence for optimization properties. perspective, synergistic approach synthesis, spectroscopy ab initio calculations has proven efficient tool construction fluorophores.

Language: Английский

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Polymerization-Induced Crystallization of Dopant Molecules: An Efficient Strategy for Room-Temperature Phosphorescence of Hydrogels

Journal of the American Chemical Society, Journal Year: 2023, Volume and Issue: 145(6), P. 3763 - 3773

Published: Feb. 7, 2023

Conventional hydrogels such as polyacrylamide and polyacrylic acid ones seldom exhibit phosphorescences at ambient conditions, which limit their applications optical materials. We propose demonstrate here a facile strategy to afford these with room-temperature phosphorescence by polymerization-induced crystallization of dopant molecules that results in segregation confinement the gel matrix carbonyl groups thus clusterization-induced phosphorescence. As model system, crown ethers (CEs) are dissolved an aqueous solution concentrated acrylamide greatly increases solubility CEs. During polymerization process, CEs crystallize form large spherulites hydrogel. The arises from drastically reduced after conversion monomers polymers during synthesis. resultant composite hydrogel water content 67 wt % exhibits extraordinary behavior yet maintains good stretchability resilience. found partial is squeezed confined situ-formed crystals, leading clusters emission. shows green emission peak 512 nm lifetime 342 ms. afterglow detectable naked eye for several seconds. This has universality, validated other different polymeric matrices molecules. development mechanical phosphorescent properties should merit design multifunctional soft machines biomedical engineering fields.

Language: Английский

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