Handbook of CH‐Functionalization,
Journal Year:
2022,
Volume and Issue:
unknown, P. 1 - 41
Published: Oct. 2, 2022
Abstract
The
activation
and
functionalization
of
the
benzylic
CH
bond
by
transition
metal
catalysts
have
gathered
much
attraction
owing
to
their
occurrence
in
agrochemicals,
pharmaceuticals,
fine
chemicals.
Among
various
active
catalysts,
ruthenium
gained
upper
hand,
as
they
are
comparatively
economic
well
show
versatile
catalytic
activity.
Ruthenium
efficiently
activates
C(sp
3
)H
effects
alkylation,
arylation,
allylation,
vinylation,
cyanation,
silylation,
amination,
amidation,
oxidation
reactions.
Advanced Synthesis & Catalysis,
Journal Year:
2020,
Volume and Issue:
362(19), P. 3987 - 4009
Published: Aug. 4, 2020
Abstract
In
recent
years,
oxidative
dehydrogenation
(ODH)
of
amines
has
proven
to
be
an
efficient,
clean
and
fundamental
route
for
the
synthesis
nitriles.
This
review
focuses
on
different
types
reactions
oxidation
nitriles
such
as
transition
metal‐catalysis,
photoactivation,
acceptorless
dehydrogenation,
nitroxyl
radical‐mediated,
N,O‐doped
mesoporous
carbon.
Emphasis
is
placed
ODH
corresponding
using
ruthenium
catalysts.
Metal
free
systems
utilizing
iodine,
TEMPO
its
derivatives,
TCCA
with
or
without
additives
are
also
discussed.
The
carbon
elaborated.
Attention
given
major
improvements,
achievements,
challenges
that
still
remain
in
field
nitrile
from
amines.
magnified
image
Catalysis Science & Technology,
Journal Year:
2021,
Volume and Issue:
11(21), P. 7018 - 7028
Published: Jan. 1, 2021
A
Ru
complex,
stabilized
by
an
annulated
mesoionic
carbene
ligand,
catalyzes
the
aerobic
oxidation
of
a
host
primary
amines
to
amides
in
high
yields
and
excellent
selectivity.
Kinetics,
Hammett
DFT
studies
provide
mechanistic
insight.
Organic & Biomolecular Chemistry,
Journal Year:
2023,
Volume and Issue:
21(11), P. 2429 - 2439
Published: Jan. 1, 2023
Amide
bonds
are
ubiquitous
and
regarded
as
an
essential
constituent
of
many
biologically
active
drug
molecules
fine
chemicals.
We
report
a
practical
operationally
simple
ruthenium-based
catalytic
system
for
the
hydration
nitriles
aerobic
oxidation
primary
amines
to
corresponding
amides.
Both
reactions
proceed
without
any
external
oxidant
in
water
under
conditions
exhibit
broad
substrate
scope.
The
mechanistic
investigation
was
executed
with
aid
control
experiments
kinetic
spectroscopic
studies
reaction
mixture.
Journal of Coordination Chemistry,
Journal Year:
2020,
Volume and Issue:
73(12), P. 1848 - 1859
Published: June 17, 2020
Three
new
ruthenium(II)
carbonyl
complexes
that
bear
phenoxy-imine
chelate
ligands,
[RN
=
CH(C6H4O)]2Ru(CO)2
(1:
R
2,6-Me2C6H3;
2:
4-OMeC6H4;
3:
4-ClC6H4)
have
been
synthesized.
These
mononuclear
were
fully
characterized
by
elemental
analysis,
FT‒IR,
and
1H
13C
NMR.
Furthermore,
the
molecular
structures
of
1-3
determined
X-ray
crystal
diffraction
analysis.
In
presence
NaHCO3
as
base,
Ru
showed
moderate
to
good
catalytic
activities
for
conversion
aldehydes
nitriles
via
dehydration
aldoximes.
Applied Organometallic Chemistry,
Journal Year:
2021,
Volume and Issue:
35(9)
Published: June 16, 2021
Abstract
Treatment
of
Ru
3
(CO)
12
with
one
equivalent
2‐indolyl‐6‐pyridinyl‐alcohol
ligands
2‐(C
8
H
6
N)‐6‐(CR
1
R
2
OH)C
5
N
(R
=
Me
(
L1H
);
C
L2H
,
−(CH
)
4
‐
L3H
);&
L4H
))
in
refluxing
THF
afforded
the
corresponding
trinuclear
ruthenium
clusters
L(μ
‐H)Ru
9
1a
–
1d
),
respectively.
All
novel
complexes
were
well
characterized
by
NMR,
elemental
analyses
and
IR
spectra.
Structures
1c
further
determined
X‐ray
crystallographic
studies.
Complexes
applied
to
catalytic
Oppenauer‐type
oxidation
secondary
alcohols
acetone
as
oxidant,
complex
was
found
be
most
efficient
catalyst.
