Structural Water Molecules Confined in Soft and Hard Nanocavities as Bright Color Emitters DOI Creative Commons
Jia‐Feng Zhou, Taiqun Yang, Bo Peng

et al.

ACS Physical Chemistry Au, Journal Year: 2021, Volume and Issue: 2(1), P. 47 - 58

Published: Oct. 14, 2021

Molecules confined in the nanocavity and nanointerface exhibit rich, unique physicochemical properties, e.g., chromophore β-barrel can of green fluorescent protein (GFP) exhibits tunable bright colors. However, physical origin their photoluminescence (PL) emission remains elusive. To mimic microenvironment GFP scaffold at molecule level, two groups nanocavities were created by self-assembly using organic chromophores functionalization mesoporous silica, respectively. We provide strong evidence that structural water molecules these are color emitters with a universal formula {X+·(OH-·H2O)·(H2O) n-1}, which X is hydrated protons (H3O+) or protonated amino (NH3+) as an anchoring point, efficiency PL strongly dependent on stability main emitter centers hydroxide complex (OH-·H2O), key intermediate to mediate electron transfer dominated proton nanospace. Further controlled experiments combined characterizations time-resolved steady-state ultrafast transient optical spectroscopy unveil unusual multichannel radiative and/or nonradiative mechanism quantum states distinctive character topological excitation. The finding this work underscores pivotal role structurally bound H2O regulating aggregation-induced luminogens GFP.

Language: Английский

Functional Mesoporous Silica Nanomaterials for Catalysis and Environmental Applications DOI Open Access
Baljeet Singh, Jongbeom Na, Muxina Konarova

et al.

Bulletin of the Chemical Society of Japan, Journal Year: 2020, Volume and Issue: 93(12), P. 1459 - 1496

Published: July 22, 2020

Abstract Silica materials are used in a wide range of applications such as catalysis, photocatalysis, CO2 capture, and environmental remediation. These nanomaterials (NMs) have been extensively investigated since the advent Stöber silica. However, absence pores small surface area silica limits its applications. Later, discovery MCM-41 type mesoporous using surfactants structural directing agents became revolutionary field NMs. This review focuses on methods for synthesizing (NMs), especially nanoparticles (NPs), their various fields including catalysis (i.e., support nanoparticle catalysts) remediation (CO to conversion, volatile organic compound (VOC) removal, capture). The current issues/challenges realizing practical these conventional also highlighted. compares characteristics MCM-41, SBA-15, KCC-1 demonstrate effect morphology pore architecture properties silica-based scope future developments synthesis with different sizes morphologies is discussed.

Language: Английский

Citations

155
Comprehensive Review of Mesoporous Silica Nanoparticles: Drug Loading, Release, and Applications as Hemostatic Agents DOI
Talib M. Albayati, Saja Mohsen Alardhi,

Ali H. Khalbas

et al.

ChemistrySelect, Journal Year: 2024, Volume and Issue: 9(23)

Published: June 18, 2024

Abstract Recently, mesoporous silica nanoparticles (MSNs) have emerged as promising candidates in the field of hemorrhage control owing to their extended pore size, high surface area, and excellent biocompatibility. These characteristics directly influence toxicity cells, loading therapeutic agents, release active ions during hemostasis process. Therefore, understanding fundamentals tuning these is important design types carriers. While several literature reviews explored role MSNs control, comprehensive studies focusing on general specific applications remain scarce. This review concentrates principles synthesizing silica, MSNs, techniques for drugs methods onto site injury, kinetics models, biocompatibility, toxicity, unique properties MSNs. Furthermore, article examines mechanism action nanomaterial hemostatic agents.

Language: Английский

Citations

32
Reinforcing Polymer Flooding System with Dendritic Mesoporous Silica Nanoparticles for Improved Oil Recovery DOI

Di Li,

Yanling Wang,

Baojun Bai

et al.

Energy & Fuels, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 14, 2025

Dendritic mesoporous silica nanoparticles (DMSNs), characterized by a high specific surface area and abundant hydroxyl groups, offer promising approach to enhancing the performance of amphiphilic polymers in challenging enhanced oil recovery (EOR) conditions. In this study, DMSNs were successfully synthesized, systematically evaluated for their impact on solution properties betaine polymer (PADC). The unique "flower-like" structure provided approximately 7-fold higher than conventional SiO2, facilitating polymer–nanoparticle interactions. DMSN/PADC composite system exhibited significantly improved viscosity, salt resistance, thermal tolerance, shear resistance compared PADC SiO2/PADC systems. Quantum chemical calculations elucidated interaction mechanisms, highlighting role silanol groups forming electrostatic interactions hydrogen bonds with PADC, thereby reinforcing three-dimensional network structure. Enhanced tests demonstrated 17.91% tertiary using system, nearly double that (9.48%). This study underscores potential as novel additive optimizing flooding formulations, enabling superior EOR high-temperature, high-salinity reservoirs.

Language: Английский

Citations

1
Dendritic mesoporous organosilica nanoparticles (DMONs): Chemical composition, structural architecture, and promising applications DOI
Yabin Wang, Baoliang Zhang,

Xiuping Ding

et al.

Nano Today, Journal Year: 2021, Volume and Issue: 39, P. 101231 - 101231

Published: July 7, 2021

Language: Английский

Citations

55
Nonordered dendritic mesoporous silica nanoparticles as promising platforms for advanced methods of diagnosis and therapies DOI
Samira Malekmohammadi, Riaz Ur Rehman Mohammed, Hadi Samadian

et al.

Materials Today Chemistry, Journal Year: 2022, Volume and Issue: 26, P. 101144 - 101144

Published: Sept. 12, 2022

Language: Английский

Citations

34
Carbon Capture Using Porous Silica Materials DOI Creative Commons
Sumedha M. Amaraweera, Chamila Gunathilake, Oneesha H. P. Gunawardene

et al.

Nanomaterials, Journal Year: 2023, Volume and Issue: 13(14), P. 2050 - 2050

Published: July 11, 2023

As the primary greenhouse gas, CO2 emission has noticeably increased over past decades resulting in global warming and climate change. Surprisingly, anthropogenic activities have atmospheric by 50% less than 200 years, causing more frequent severe rainfall, snowstorms, flash floods, droughts, heat waves, rising sea levels recent times. Hence, reducing excess atmosphere is imperative to keep average temperature rise below 2 °C. Among many mitigation approaches, capture using porous materials considered one of most promising technologies. Porous solid such as carbons, silica, zeolites, hollow fibers, alumina been widely investigated Interestingly, silica-based recently emerged excellent candidates for technologies due their unique properties, including high surface area, pore volume, easy functionalization, thermal, mechanical stability, low cost. Therefore, this review comprehensively covers major processes pros cons, selecting a suitable sorbent, use liquid amines, highlights progress various silica materials, amine-functionalized reaction mechanisms synthesis processes. Moreover, adsorption capacities, gas selectivity, reusability, current challenges, future directions also discussed.

Language: Английский

Citations

22
Isorhamnetin and anti-PD-L1 antibody dual-functional mesoporous silica nanoparticles improve tumor immune microenvironment and inhibit YY1-mediated tumor progression DOI Creative Commons
Huijuan Liu,

Jingxia Han,

Ying Lv

et al.

Journal of Nanobiotechnology, Journal Year: 2023, Volume and Issue: 21(1)

Published: July 5, 2023

The immune checkpoint inhibitor (ICI) anti-PD-L1 monoclonal antibody can inhibit the progress of hepatocellular carcinoma (HCC). Epithelial-mesenchymal transformation (EMT) promote tumor migration and formation immune-suppression microenvironment, which affects therapeutic effect ICI. Yin-yang-1 (YY1) is an important transcription factor regulating proliferation, EMT cells. This work proposed a drug-development strategy that combined regulation YY1-mediated progression with ICIs for treatment HCC.We first studied proteins regulated YY1 expression by using pull-down, co-immunoprecipitation, duo-link assay. active compound content was screened virtual screening cell-function Isorhamnetin (ISO) dual-functional mesoporous silica nanoparticles (HMSN-ISO@ProA-PD-L1 Ab) were prepared as antitumor drug to play synergistic anti-tumor role.YY1 specifically bind deubiquitination enzyme USP7. USP7 prevent from ubiquitin-dependent degradation stabilize expression, HCC out, target degradation. cell experiments revealed HMSN-ISO@ProA-PD-L1 Ab cells role in controlled release ISO. inhibited growth Hepa1-6 transplanted tumors better than PD-L1 group ISO group. also exerted promising on reducing MDSC microenvironment promoting T-cell infiltration tumors.The isorhamnetin improve progression. study demonstrated possibility strategies based inhibiting USP7-mediated Ab.

Language: Английский

Citations

18
Dendritic Mesoporous Nanoparticles: Structure, Synthesis and Properties DOI Creative Commons
C. F. Xu, Chang Lei, Yue Wang

et al.

Angewandte Chemie, Journal Year: 2021, Volume and Issue: 134(12)

Published: Nov. 27, 2021

Abstract Recently, dendritic mesoporous silica nanoparticles with widespread applications have attracted great interest. Despite many publications (>800), the terminology “dendritic” is ambiguous. Understanding what possible “dendritic structures” are, their formation mechanisms and underlying structure–property relationship fundamentally important. With advance of characterization techniques such as electron tomography, two types tree‐branch‐like flower‐like structures can be distinguished, both described in literature. In this Review, we start definition “dendritic”, then provide critical analysis reported according to structural classification. We update understandings nanoparticles, highlighting how control parameters. Applications are also reviewed a focus on biomedical field, providing new insights into family nanomaterials.

Language: Английский

Citations

41
The Capture and Catalytic Conversion of CO2 by Dendritic Mesoporous Silica‐Based Nanoparticles DOI Creative Commons
Yabin Wang, Liang‐Zhu Huang, Songwei Li

et al.

Energy & environment materials, Journal Year: 2023, Volume and Issue: 7(2)

Published: Jan. 31, 2023

Dendritic mesoporous silica nanoparticles own three‐dimensional center‐radial channels and hierarchical pores, which endows themselves with super‐high specific surface area, extremely large pore volumes, especially accessible internal spaces, so forth. Dissimilar guest species (such as organic groups or metal nanoparticles) could be readily decorated onto the interfaces of realizing functionalization dendritic for targeted applications. As adsorbents catalysts, nanoparticles‐based materials have experienced nonignorable development in CO 2 capture catalytic conversion. This comprehensive review provides a critical survey on this pregnant subject, summarizing designed construction novel materials, involved chemical reactions methanation, dry reforming CH 4 ), value‐added chemicals from cyclic carbonates, 2‐oxazolidinones, quinazoline‐2,4(1 H ,3 )‐diones), on. The adsorptive performances been compared traditional SBA‐15 MCM‐41), corresponding reaction mechanisms thoroughly revealed. It is sincerely expected that in‐depth discussion give scientists certain inspiration to design brand‐new superior capabilities towards capture, utilization, storage.

Language: Английский

Citations

14
Enhancing Dendritic Cell Activation Through Manganese-Coated Nanovaccine Targeting the cGAS-STING Pathway DOI Creative Commons
Qiyu Wang, Ying Gao, Qiang Li

et al.

International Journal of Nanomedicine, Journal Year: 2024, Volume and Issue: Volume 19, P. 263 - 280

Published: Jan. 1, 2024

Background: Nanovaccines have emerged as a promising vaccination strategy, exhibiting their capacity to deliver antigens and adjuvants elicit specific immune responses. Despite this potential, optimizing the design delivery of nanovaccines remains challenge. Methods: In study, we engineered dendritic mesoporous silica-based nanocarrier enveloped in metal-phenolic network (MPN) layer containing divalent manganese ions tannic acid (MSN@MT). This was tailored for antigen loading serve nanovaccine, aiming activate cyclic GMP-AMP synthase-stimulator interferon genes (cGAS-STING) pathway cells (DCs). Our experimental approach encompassed both cellular assays mouse immunizations, allowing comprehensive evaluation nanovaccine's impact on DC activation its influence generation antigen-specific T-cell Results: MSN@MT demonstrated remarkable enhancement humoral responses mice compared control groups. highlights potential effectively trigger cGAS-STING DCs, resulting robust Conclusion: study introduces MSN@MT, unique incorporating acid, showcasing exceptional ability amplify by activating DCs. innovation signifies stride refining nanovaccine potent activation. Keywords: nanocarrier, network, ions,

Language: Английский

Citations

6