Fortschritte der Chemie Organischer Naturstoffe/Fortschritte der Chemie organischer Naturstoffe/Progress in the chemistry of organic natural products,
Journal Year:
2022,
Volume and Issue:
unknown, P. 101 - 130
Journal of Natural Products,
Journal Year:
2021,
Volume and Issue:
84(12), P. 3055 - 3063
Published: Nov. 19, 2021
Rugonidines
A–F
(1–6),
three
pairs
of
novel
configurationally
semistable
diastereomers
featuring
an
unprecedented
1,6-dioxa-7,9-diazaspiro[4.5]dec-7-en-8-amine
scaffold,
were
isolated
from
Alchornea
rugosa
based
on
MS/MS-based
molecular
networking
analysis.
Their
structures
elucidated
by
NMR
spectroscopy
in
combination
with
quantum-chemical
calculations.
Compounds
1–3
showed
a
significant
increase
glucose
uptake
level
differentiated
3T3-L1
adipocytes
using
2-deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-d-glucose
(2-NBDG)
as
fluorescent-tagged
probe.
The Journal of Physical Chemistry Letters,
Journal Year:
2021,
Volume and Issue:
12(31), P. 7418 - 7422
Published: July 30, 2021
Supramolecular
assemblies
based
on
oligo(ethylene
glycol)
(OEG)
building
blocks
are
well-known
for
their
neutral
chemical
property
and
thermal-responsive
behavior.
Here,
the
cyclic
"CLOSED"
linear
"OPEN"
typologies
of
OEGs
led
to
dramatic
difference
in
sensitivity
guanidinium-containing
species.
From
thermodynamic
studies,
association
constant
(Ka)
between
form
amphiphile
guanidinium
salt
was
determined
be
28.7
M–1,
whereas
there
no
detectable
binding
affinity
form.
Therefore,
considering
ion
specificity,
present
results
establish
that
crown
ether
derivatives
with
topologies
provide
an
easy-to-access
model
pair
designed
ion-recognition
sites
special
functional
moieties
geometries
(like
pockets
enzymes
or
channels
cellular
members)
allow
manipulation
intercrossed
relationship
supramolecular
solutes,
waters,
salts.
These
forces
aqueous
solution
offered
alternative
strategy
fabricate
systems
ionic
medium.
Fortschritte der Chemie Organischer Naturstoffe/Fortschritte der Chemie organischer Naturstoffe/Progress in the chemistry of organic natural products,
Journal Year:
2022,
Volume and Issue:
unknown, P. 101 - 130
