Organic Letters,
Journal Year:
2024,
Volume and Issue:
26(31), P. 6652 - 6657
Published: July 26, 2024
We
report
a
visible-light-promoted
cyclization/sulfonylation
cascade
of
N-heterocycles
with
thianthrenium
salts
using
DABSO
as
the
SO2
surrogate.
This
method
features
excellent
functional
group
tolerance,
wide
substrate
scope,
and
late-stage
elaboration
bioactive
relevant
molecules.
Mechanistic
investigations
reveal
that
photoactive
electron
donor–acceptor
(EDA)
complexes
between
DABCO
are
capable
generation
aryl
radicals,
which
induce
following
insertion
by
attacking
DABSO,
thus
triggering
key
radical
cyclization
step.
Chemical Society Reviews,
Journal Year:
2022,
Volume and Issue:
51(19), P. 8351 - 8377
Published: Jan. 1, 2022
This
review
focuses
on
nickel-catalyzed
construction
and
transformation
of
various
sulfide-containing
compounds,
such
as
sulfides,
disulfides,
hypervalent
sulfur-containing
compounds.
Nature Communications,
Journal Year:
2025,
Volume and Issue:
16(1)
Published: Jan. 29, 2025
A
chemical
reagent
to
access
methyl
sulfones
has
been
developed.
Its
reaction
with
various
bis-nucleophiles
leads
the
rapid
formation
of
previously
unknown
heteroaromatic
sulfones.
Analogous
strategy
can
also
be
used
construct
alkyl-,
CHF2-,
CF3-
and
even
bicyclo[1.1.1]pentane-containing
derivatives.
These
compounds
have
demonstrated
a
high
potential
for
use
in
medicinal
chemistry
coordination
chemistry.
Methyl
sulfone
is
standard
polar
substituent
found
different
agro
chemicals
or
drugs
but
due
lack
convenient
efficient
approaches
them,
are
less
investigated.
Here
authors
report
The Chemical Record,
Journal Year:
2021,
Volume and Issue:
21(12), P. 3338 - 3355
Published: Jan. 26, 2021
Abstract
Sulfonyl
compounds
have
attracted
considerable
interest
due
to
their
extensive
applications
in
drug
discovery,
agricultural,
and
material
science.
The
access
the
assembly
of
SO
2
‐containing
via
same
oxidative‐state
introduction
hypervalent
sulfur
has
come
fore
recent
years.
Especially,
transition‐metal‐involved
synthesis
is
most
effective
strategy
since
easy
insert
into
metal‐carbon
bonds.
This
review
discusses
application
oxidation‐state
under
transition‐metal‐catalyzed
conditions,
presents
according
different
metal
catalysts
synthesized
diversity
sulfur‐containing
skeletons,
including
sulfonamides,
sulfones,
sulfinamides,
sulfonyl
acids
fluorides.
Organic Letters,
Journal Year:
2021,
Volume and Issue:
23(9), P. 3663 - 3668
Published: April 21, 2021
An
efficient
visible-light-assisted,
copper-catalyzed
sulfonylation
of
aryl
halides
with
sulfinates
is
reported.
In
our
protocol,
a
single
ligand
CuI
photocatalyst
formed
in
situ
was
used
the
photocatalytic
transformation.
Diverse
organosulfones
were
obtained
moderate
to
good
yields.
This
strategy
demonstrates
promising
approach
toward
synthesis
diverse
and
useful
organosulfones.
Advanced Agrochem,
Journal Year:
2022,
Volume and Issue:
2(1), P. 3 - 14
Published: Dec. 21, 2022
As
well
known,
with
the
increase
of
world
population,
improving
agricultural
production
has
always
been
great
importance.
Due
to
effective
protection
against
pests
or
pathogenic
bacteria
and
promoting
growth
crops,
agrochemical
holds
vital
position
in
modern
agriculture.
In
this
field,
introducing
sulfur
moieties
into
active
ingredients
improve
property
pesticides
a
powerful
tool
for
development
agrochemical.
Thus,
efficient
methods
construction
organosulfur
scaffolds
existed
agrochemicals
are
highly
desirable,
which
also
attract
considerable
attentions
over
past
few
decades.
Herein,
we
provide
comprehensive
introduction
representative
synthetic
access
sulfur-containing
molecules
frequently
found
utilization
various
sulfurizing
agents,
point
out
potential
direction
further
development.
Chemical Science,
Journal Year:
2021,
Volume and Issue:
12(27), P. 9359 - 9365
Published: Jan. 1, 2021
A
three-component
aminofluorosulfonylation
of
unactivated
alkenes
has
been
developed
by
merging
photocatalytic
PCET
with
radical
relay
processes,
affording
various
aliphatic
sulfonyl
fluorides
featuring
medicinally
privileged
heterocyclic
scaffolds.
Organic Letters,
Journal Year:
2022,
Volume and Issue:
24(15), P. 2955 - 2960
Published: April 13, 2022
A
photoredox-catalyzed
sulfonylation
of
silyl
enol
ethers
with
DABCO·(SO2)2
and
thianthrenium
salts
is
achieved,
providing
diverse
β-keto
sulfones
in
moderate
to
good
yields.
This
protocol
features
easily
accessible
starting
materials
functional
group
compatibility,
enabling
the
introduction
various
functionalized
sulfonyl
groups
into
ketones.
Furthermore,
as
one
important
industrial
raw
materials,
methanol
can
be
employed
methyl
source
prepare
α-methylsulfonated
ketones
through
a
intermediate
for
first
time.
Angewandte Chemie International Edition,
Journal Year:
2023,
Volume and Issue:
62(16)
Published: Feb. 10, 2023
We
herein
report
a
method
that
enables
the
generation
of
glycosyl
radicals
under
highly
acidic
conditions.
Key
to
success
is
design
and
use
sulfinates
as
radical
precursors,
which
are
bench-stable
solids
can
be
readily
prepared
from
commercial
starting
materials.
This
development
allows
installation
units
onto
pyridine
rings
directly
by
Minisci
reaction.
further
demonstrate
utility
this
in
late-stage
modification
complex
drug
molecules,
including
anticancer
agent
camptothecin.
Experimental
studies
provide
insight
into
reaction
mechanism.
