Nature Communications,
Journal Year:
2022,
Volume and Issue:
13(1)
Published: Oct. 16, 2022
Abstract
Developing
photo-induced
cascade
cyclization
of
alkene-tethered
acylsilanes
is
challenging,
because
are
unstable
under
light
irradiation.
Herein,
we
report
that
the
energy
transfer
from
excited
to
a
photocatalyst
possesses
lower
triplet
can
inhibit
undesired
decomposition
acylsilanes.
With
neutral
Eosin
Y
as
photocatalyst,
an
efficient
synthesis
cyclopentanol
derivatives
achieved
with
and
allylic
sulfones.
The
reaction
shows
broad
substrate
scope
synthetic
potential
this
transformation
highlighted
by
construction
which
contain
fused-ring
or
bridged-ring.
Organic Letters,
Journal Year:
2022,
Volume and Issue:
24(2), P. 642 - 647
Published: Jan. 5, 2022
A
direct
alkoxycarbonylation/cyclization
reaction
is
accomplished
under
visible
light-induced
photoredox
catalysis.
With
this
approach,
a
variety
of
ester-substituted
indolo[2,1-a]isoquinolines
are
prepared
in
good
to
excellent
yields.
It
worth
noting
that
method
not
only
can
afford
the
synthesis
but
also
provide
an
alternative
route
for
generating
complex
target
structures
bearing
carboxylic
esters.
Beilstein Journal of Organic Chemistry,
Journal Year:
2023,
Volume and Issue:
19, P. 1055 - 1145
Published: July 28, 2023
Photoredox
catalysis
(PRC)
is
a
cutting-edge
frontier
for
single
electron-transfer
(SET)
reactions,
enabling
the
generation
of
reactive
intermediates
both
oxidative
and
reductive
processes
via
photon
activation
catalyst.
Although
this
represents
significant
step
towards
chemoselective
and,
more
generally,
sustainable
chemistry,
its
efficacy
limited
by
energy
visible
light
photons.
Nowadays,
excellent
alternative
conditions
are
available
to
overcome
these
limitations,
harvesting
two
different
but
correlated
concepts:
use
multi-photon
such
as
consecutive
photoinduced
electron
transfer
(conPET)
combination
photo-
electrochemistry
in
synthetic
photoelectrochemistry
(PEC).
Herein,
we
review
most
recent
contributions
fields
activations
organic
functional
groups.
New
opportunities
chemists
captured,
selective
reactions
employing
super-oxidants
super-reductants
engage
unactivated
chemical
feedstocks,
scalability
up
gram
scales
continuous
flow.
This
provides
comparisons
between
techniques
(multi-photon
photoredox
PEC)
help
reader
fully
understand
their
similarities,
differences
potential
applications
therefore
choose
which
method
appropriate
given
reaction,
scale
purpose
project.
Green Synthesis and Catalysis,
Journal Year:
2024,
Volume and Issue:
5(4), P. 211 - 269
Published: May 6, 2024
The
development
of
catalytic
carbonylation
reactions
has
increased
considerably.
Although
many
reviews/chapters/books
on
have
been
published,
summaries
cheap
metal-catalyzed
aryl
halides
and
other
chemical
bonds
with
high
dissociation
energy
C-Y
(Y
=
O,
N,
H)
are
still
very
rare.
Focusing
green
sustainable
chemistry,
this
review
summarizes
discusses
the
achievements
carbonylative
transformations
(C(sp2)-X)
strong
based
non-expensive
metal
catalysts
(Co,
Mn,
Mo,
Ni,
Fe,
Cu),
photochemical
electrochemical
systems
developed
in
recent
decades.
Organic Letters,
Journal Year:
2024,
Volume and Issue:
26(18), P. 3828 - 3833
Published: April 29, 2024
The
photocatalyzed
radical-triggered
thio/selenosulfonylation–bicyclization
of
indole-tethered
1,6-enynes
has
been
established
for
the
first
time,
enabling
synthesis
various
previously
unreported
thio/selenosulfonylated
benzo[c]pyrrolo[1,2,3-lm]carbazoles
with
moderate
to
good
yields
under
mild
conditions.
reaction
pathway
was
proposed,
consisting
energy
transfer,
homolytic
cleavage,
radical
addition,
5-exo-dig,
coupling,
and
a
Mallory
cascade.
This
approach
exhibits
wide
substrate
compatibility
excellent
tolerability
toward
functional
groups
is
characterized
by
its
remarkable
efficiency
in
both
bond
formation
annulation.
Advanced Science,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 28, 2025
Abstract
Transition‐metal‐catalyzed
transformations
offer
a
powerful
approach
to
rapidly
synthesize
complex
benzo‐fused
heterocycles,
crucial
for
drug
and
material
development.
However,
existing
synthetic
strategies
face
challenges
such
as
limited
functional
group
compatibility,
reliance
on
ligands,
difficulties
in
controlling
chemoselectivity
with
prefunctionalized
substrates.
Herein,
ligand‐free
Pd(II)/Cu(I)
catalytic
system
is
presented
that
facilitates
reactions
between
arylsulfonyl
chlorides
unactivated
olefins
under
mild
conditions,
enabling
the
efficient
synthesis
of
saturated
six‐membered
heterocycles.
This
streamlined
strategy
employs
dual
Csp
2
─Csp
3
bond
formation,
producing
diverse
N/O‐polyheterocycles
allowing
late‐stage
functionalization
bioactive
molecules
excellent
yields
high
chemoselectivity.
The
key
success
this
reaction
formation
high‐valent
Ar‐Pd(III)
intermediate,
which
drives
through
1,2‐Pd
migration
electrophilic
C─H
arylation.
unique
reactivity
pathway
heterocycles
while
effectively
avoiding
β‐H
elimination
typically
associated
Heck‐type
reactions.
Advanced Synthesis & Catalysis,
Journal Year:
2022,
Volume and Issue:
364(9), P. 1537 - 1542
Published: March 11, 2022
Abstract
Iron‐catalyzed
cascade
silyl
radical
addition/6‐
exo
‐trig
cyclization/dearomatization
of
biaryl
ynones
has
been
developed.
This
approach
uses
silane
as
the
precursor
well
silylation
reagent,
1,10‐phenanthroline
ligand,
and
tert
‐butyl
hydroperoxide
(TBHP)
oxidant.
By
employing
this
tandem
process,
a
series
silylated
spiro[5.5]trienones
were
prepared.
magnified
image
