Journal of Heterocyclic Chemistry,
Journal Year:
2023,
Volume and Issue:
60(6), P. 1047 - 1057
Published: March 26, 2023
Abstract
We
report
a
facile
method
to
synthesize
novel
alkyl
selanyl[1,2,4]triazolo[4,3‐
]pyrimidine
heterocyclic
scaffolds.
A
diverse
library
of
selenide
derivatives
has
been
prepared
via
the
treatment
5‐bromo‐2,4‐dichloro‐6‐methylpyrimidine
with
potassium
selenocyanate
as
source
selenium.
The
anion
nucleophile
is
applied
produce
5‐bromo‐2‐chloro‐4‐methyl‐6‐selenocyanatopyrimidine
(
2
).
interaction
compound
)
various
halides
afforded
selanyl
pyrimidine
3a
–
e
Then,
hydrazine
hydrate
gave
corresponding
4a
which
react
orthoesters
prepare
relative
5a
o
in
good
excellent
yields.
chemical
structures
whole
products
have
evaluated
by
spectroscopic
analyses.
ACS Applied Nano Materials,
Journal Year:
2023,
Volume and Issue:
6(3), P. 1724 - 1731
Published: Jan. 20, 2023
The
development
of
highly
efficient
nonnoble
metals
toward
hydrogen
evolution
reaction
(HER)
electrocatalysts
is
significant
for
producing
via
water
electrolysis.
Selenides
are
becoming
increasingly
attractive
owing
to
their
excellent
HER
activity.
Herein,
CoSe2
nanorods
were
successfully
manufactured
on
a
carbon
cloth
(CC)
and
selenium
vacancies
obtained
using
plasma
cleaner
(CoSe2-VSe/CC)
enhance
intrinsic
catalytic
synthetic
catalyst
exhibited
lower
overpotential
88
mV
at
10
mA
cm–2
in
1
M
KOH
high
durability
over
100
h
cm–2,
which
can
be
ascribed
the
increased
electrochemical
surface
area
rapid
electron
transfer.
In
addition,
density
functional
theory
(DFT)
calculations
showed
that
introducing
Se
optimized
adsorption
energy
site
reduced
transition-state
barrier
dissociation.
This
study
laid
firm
foundation
preparing
high-performance
stable
anion
defect
engineering.
Organic & Biomolecular Chemistry,
Journal Year:
2021,
Volume and Issue:
20(1), P. 117 - 121
Published: Nov. 27, 2021
Selenium-substituted
heteroarenes
are
biologically
active
compounds
and
useful
building
blocks.
In
this
study,
we
have
developed
a
metal-
oxidant-free,
environmentally
friendly
protocol
for
the
regioselective
selenylation
of
2H-indazole
derivatives
by
an
electrochemical
strategy.
A
number
selenylated
2H-indazoles
with
wide
range
functional
groups
been
synthesized
in
moderate
to
good
yields
under
mild
environment-friendly
reaction
conditions.
Organic & Biomolecular Chemistry,
Journal Year:
2023,
Volume and Issue:
22(4), P. 645 - 681
Published: Dec. 23, 2023
Organochalcogen
compounds
are
prevalent
in
numerous
natural
products,
pharmaceuticals,
agrochemicals,
polymers,
biological
molecules
and
synthetic
intermediates.
Direct
chalcogenation
of
C-H
bonds
has
evolved
as
a
step-
atom-economical
method
for
the
synthesis
chalcogen-bearing
compounds.
Nevertheless,
direct
severely
lags
behind
C-C,
C-N
C-O
bond
formations.
Moreover,
compared
with
monochalcogenation,
reports
selective
mono-/dichalcogenation
exclusive
dichalcogenation
relatively
scarce.
The
past
decade
witnessed
significant
advancements
various
C(sp
Foods,
Journal Year:
2023,
Volume and Issue:
12(20), P. 3773 - 3773
Published: Oct. 13, 2023
The
selenization
of
natural
products
refers
to
the
chemical
modification
method
artificially
introducing
selenium
atoms
into
interact
with
functional
groups
in
target
molecule
form
selenides.
Nowadays,
even
though
scientists
fields
involving
organic
compounds
have
achieved
numerous
results
due
their
continuous
investment,
few
comprehensive
and
systematic
summaries
relating
research
can
be
found.
present
paper
summarizes
methods
several
kinds
important
products,
such
as
polysaccharides,
proteins/polypeptides,
polyphenols,
lipids,
cyclic
compounds,
well
basic
principles
or
mechanisms
selenizing
methods.
On
this
basis,
explored
future
development
trend
field
selenized
it
is
hoped
provide
some
suggestions
for
directional
application
active
ingredients.
Scientific Reports,
Journal Year:
2023,
Volume and Issue:
13(1)
Published: Aug. 31, 2023
In
this
paper,
we
report
an
eco-friendly
approach
for
the
C(sp2)-H
bond
selenylation
of
imidazopyridines
and
other
N-heteroarenes
as
well
simple
arenes
at
ambient
temperature.
This
new
protocol
consists
reaction
between
(N-hetero)-arenes
diorganyl-diselenides
trichloroisocyanuric
acid
(TCCA)-ethanol
reagent
system.
a
short
time,
desired
selenylated
products
were
obtained
regioselectively
in
good
yields,
with
tolerance
wide
range
functional
groups.
ChemistrySelect,
Journal Year:
2024,
Volume and Issue:
9(1)
Published: Jan. 2, 2024
Abstract
A
mild
Oxone®
mediated
reaction
for
direct
regioselective
C−H
selenylation
and
thiocyanation
of
pyrazolo[1,5‐
a
]pyrimidines
is
established
at
ambient
temperature.
This
practical
efficient
methodology
employs
as
user
friendly,
green,
non‐toxic
cheap
reagent
to
facilitate
room
The
present
method
offers
high
regioselectivity,
broad
substrate
scope,
conditions
excellent
yields.
Further,
this
eco‐friendly
approach
could
easily
be
extended
other
heterocycles.
Mechanistic
studies
indicate
that
the
occurs
through
electrophilic
substitution
mechanism
via
generation
an
chalcogen
species.
Chemical Communications,
Journal Year:
2021,
Volume and Issue:
58(1), P. 96 - 99
Published: Nov. 29, 2021
Metal-free
C-Se
cross-couplings
via
the
formation
of
electron-donor-acceptor
(EDA)
complexes
have
been
developed.
The
visible-light
induced
reactions
can
be
applied
for
synthesis
a
series
unsymmetrical
diaryl
selenides
employing
aryl
bromides,
iodides
as
well
chlorides
under
mild
reaction
conditions.
scale-up
was
readily
achieved.
UV-Vis
spectroscopy
measurements
provide
insight
into
mechanism.
Organic & Biomolecular Chemistry,
Journal Year:
2022,
Volume and Issue:
20(14), P. 2813 - 2817
Published: Jan. 1, 2022
An
efficient
electrochemical
method
for
the
direct
synthesis
of
complicated
1,3-diselenyl-dihydroisobenzofurans
was
developed
under
external
oxidant
free
conditions
at
room
temperature
from
substituted
o-divinylbenzenes
and
diselenides.
A
radical
mechanism
is
proposed
this
novel
practical
transformation.
