Journal of Heterocyclic Chemistry,
Journal Year:
2023,
Volume and Issue:
60(6), P. 1047 - 1057
Published: March 26, 2023
Abstract
We
report
a
facile
method
to
synthesize
novel
alkyl
selanyl[1,2,4]triazolo[4,3‐
]pyrimidine
heterocyclic
scaffolds.
A
diverse
library
of
selenide
derivatives
has
been
prepared
via
the
treatment
5‐bromo‐2,4‐dichloro‐6‐methylpyrimidine
with
potassium
selenocyanate
as
source
selenium.
The
anion
nucleophile
is
applied
produce
5‐bromo‐2‐chloro‐4‐methyl‐6‐selenocyanatopyrimidine
(
2
).
interaction
compound
)
various
halides
afforded
selanyl
pyrimidine
3a
–
e
Then,
hydrazine
hydrate
gave
corresponding
4a
which
react
orthoesters
prepare
relative
5a
o
in
good
excellent
yields.
chemical
structures
whole
products
have
evaluated
by
spectroscopic
analyses.
Chemical Communications,
Journal Year:
2024,
Volume and Issue:
60(74), P. 10156 - 10159
Published: Jan. 1, 2024
An
efficient
chalcogenative
annulation
strategy
for
constructing
functionalized
saturated
N-heterocycles
from
unactivated
alkenes
with
dichalcogenides
under
electrochemical
conditions
has
been
presented.
This
protocol
is
applicable
to
mono-,
di-
or
tri-substituted
alkenes,
providing
a
straightforward
pathway
aziridines,
azetidines,
pyrrolidines,
and
piperidines
high
regioselectivity.
Moreover,
the
qualified
realize
oxychalcogenation
of
as
well.
Synthesis,
Journal Year:
2022,
Volume and Issue:
54(10), P. 2487 - 2493
Published: Jan. 4, 2022
Abstract
A
metal-free
direct
C–H
selenation
of
aniline
derivatives
via
an
iodine-catalyzed
C–Se
bond
formation
using
diselenides
as
a
selenium
source
at
ambient
temperature
is
described.
variety
underwent
regioselective
with
different
to
afford
the
corresponding
aryl
selenoethers
in
good
excellent
yields.
Synlett,
Journal Year:
2023,
Volume and Issue:
34(12), P. 1381 - 1384
Published: March 31, 2023
Abstract
A
nickel-catalyzed
C–Se
cross-coupling
between
aryl
iodides
and
selenols
is
described.
The
newly
developed
catalytic
methodology
offers
facile
access
to
various
unsymmetrical
selenium-containing
motifs.
reaction
features
excellent
functional
group
tolerance,
wide
substrate
scope,
good
efficiency,
operates
under
mild
conditions.
Notably,
this
protocol
could
be
readily
scaled
up
gram
scale
without
the
loss
of
yield.
European Journal of Organic Chemistry,
Journal Year:
2022,
Volume and Issue:
2022(41)
Published: Oct. 5, 2022
Abstract
An
environmentally
friendly
and
efficient
electrochemical
fluoroselenation
reaction
of
olefins
has
been
developed.
With
the
use
commercially
available
diaryl
diselenides,
triethylamine
trihydrofluoride,
olefins,
a
diverse
array
β‐fluoroselenides
could
be
readily
obtained.
The
conditions
are
mild,
tolerating
wide
range
substrates
in
excellent
yields
selectivity,
can
easily
extended
to
gram‐scale
preparation
vicinal
fluoroselenides,
too.
Synthesis,
Journal Year:
2023,
Volume and Issue:
55(21), P. 3693 - 3699
Published: July 6, 2023
Abstract
A
new
method
has
been
developed
for
the
C–H
selenylation
of
pyrazolo[1,5-a]pyrimidine
derivatives
under
irradiation
visible
light.
This
photocatalyst-free
strategy
is
applicable
to
a
wide
range
pyrazolo[1,5-a]pyrimidines
with
broad
functionalities.
The
salient
features
are
mild
reaction
conditions,
use
bench-stable
oxidant,
high
regioselectivity,
and
scalability.
Green Chemistry Letters and Reviews,
Journal Year:
2022,
Volume and Issue:
15(2), P. 373 - 382
Published: April 3, 2022
We
describe
a
simple
and
environment-friendly
visible
light-promoted
protocol
to
access
2-aryl-(3-organoselanyl)thieno[2,3-b]pyridines,
through
the
selenocyclization
of
3-(arylethynyl)-2-(alkylthio)pyridines
in
presence
diorganyl
diselenides
as
selenium
source.
The
Se-based
reactive
species
were
generated
situ
by
homolytic
Se-Se
bond
cleavage
using
blue
LED
an
O2
atmosphere
at
room
temperature.
was
suitable
for
wide
range
substrates
bearing
different
substituents,
allowing
synthesis
twenty-one
thieno[2,3-b]pyridines
good
excellent
yields
(57–99%).
ACS symposium series,
Journal Year:
2024,
Volume and Issue:
unknown, P. 35 - 79
Published: May 14, 2024
This
chapter
reviews
the
historical
development
and
recent
advancements
in
copper-catalyzed
coupling
reactions,
focusing
on
emerging
field
of
nanostructured
copper
catalysts.
We
explore
superior
catalytic
efficiency
these
nanostructures
compared
to
traditional
catalysts,
attributing
their
enhanced
performance
size,
shape,
large
surface
area.
Successful
C–C,
C–heteroatom
bond-forming
reactions
is
highlighted,
accompanied
by
notable
recyclability
nanoparticles
(CuNPs)
without
loss
efficacy.
While
specific
like
Ullmann
Sonogashira
types
have
been
extensively
studied,
gaps
understanding
persist,
pointing
untapped
potential
various
reactions.
The
anticipates
future
developments
highly
efficient
sustainable
emphasizing
ongoing
interest
green
chemistry.
Continued
research
into
mechanisms
encouraged
unlock
full
copper-based
nanomaterials
Organic Chemistry Frontiers,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 13, 2024
Development
of
novel
and
efficient
synthetic
methods
to
achieve
valuable
N-heterocycles
from
aryldiazonium
salts
has
been
an
important
research
area
in
organic
chemistry
for
several
decades.
