Abstract
Electrosynthesis
of
selenylated‐oxazolone
derivatives
via
cascade
selenylation/cyclization
ynamides
was
disclosed.
A
series
diaryl
diselenides,
dialkyl
and
heteroaryl‐substituted
tolerated
in
this
protocol
delivered
4‐selenyloxazolones
28–83%
yields.
The
scale‐up
reaction
the
oxidation
performed
to
showcase
practicability
method.
Furthermore,
mechanistic
experiments
indicated
that
a
cationic
pathway
instead
radical
probably
involved.
Green Synthesis and Catalysis,
Journal Year:
2023,
Volume and Issue:
unknown
Published: Oct. 1, 2023
We
first
describe
a
photoinduced
decatungstate-catalyzed
direct
coupling
of
cycloalkanes
and
cyclic
aldimines.
The
desired
products
were
generated
in
moderate
to
good
yields
with
wide
substrate
scope
under
mild
reaction
conditions.
mechanistic
study
revealed
radical
process.
In
addition,
the
usefulness
organic
synthesis
was
proved
by
scale-up
as
well
late-stage
modification
drug-like
molecules.
Chemical Communications,
Journal Year:
2024,
Volume and Issue:
60(74), P. 10196 - 10199
Published: Jan. 1, 2024
A
method
for
inducing
direct
selenothiocyanation
from
both
terminal
and
internal
alkynes
through
a
radical
process
is
proposed
under
metal-free
conditions.
Abstract
Electrosynthesis
of
selenylated‐oxazolone
derivatives
via
cascade
selenylation/cyclization
ynamides
was
disclosed.
A
series
diaryl
diselenides,
dialkyl
and
heteroaryl‐substituted
tolerated
in
this
protocol
delivered
4‐selenyloxazolones
28–83%
yields.
The
scale‐up
reaction
the
oxidation
performed
to
showcase
practicability
method.
Furthermore,
mechanistic
experiments
indicated
that
a
cationic
pathway
instead
radical
probably
involved.
