Visible-light-induced direct 3-ethoxycarbonylmethylation of 2-aryl-2H-indazoles in water

Organic Chemistry Frontiers, Journal Year: 2022, Volume and Issue: 9(5), P. 1445 - 1450

Published: Jan. 1, 2022

A visible-light-driven rhodamine B-catalyzed transition-metal-free 3-ethoxycarbonylmethylation of 2-aryl-2 H -indazoles and imidazo[1,2- a ]pyridines (40 examples) using commercially available α-bromoesters was realized in water.

Language: Английский

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Visible-Light-Induced, Palladium-Catalyzed 1,4-Difunctionalization of 1,3-Dienes with Bromodifluoroacetamides

Organic Letters, Journal Year: 2022, Volume and Issue: 24(3), P. 924 - 928

Published: Jan. 18, 2022

A highly modular 1,4-difunctionalization of 1,3-dienes with bromodifluoroacetamides and sulfinates/amines through a photoinduced palladium-catalyzed radical relay process is described herein. This developed protocol offers facile general route to access variety value-added CF2-incorporated alkenes in moderate good yields. The versatility flexibility this approach have been well illustrated by readily accessible starting materials, synthetic convenience, wide functional group compatibility.

Language: Английский

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α-Amino Radical-Mediated Difunctionalization of Alkenes with Polyhaloalkanes and N-Heteroarenes

Organic Letters, Journal Year: 2023, Volume and Issue: 25(11), P. 1994 - 1998

Published: March 15, 2023

Herein, we report a mild and practical protocol for the α-perchloroalkyl β-heteroarylation of alkenes using available chloroform as dichloromethyl source via α-amino radical-mediated halogen-atom transfer. Various substrates are compatible under reaction conditions, providing corresponding products in moderate to good yields. This strategy gives an efficient convenient method introduction chloroalkyl motifs into N-heteroarenes. The control experiment demonstrates that radical generated situ is key intermediate transformation.

Language: Английский

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Electrochemical radical annulation of 2-alkynyl biaryls with diselenides under catalyst- and chemical oxidant-free conditions

Chinese Chemical Letters, Journal Year: 2023, Volume and Issue: 34(12), P. 108699 - 108699

Published: June 17, 2023

Language: Английский

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Recent advances on application nanomagnetic recoverable catalysts for synthesis of 1,4-dihydropyridine (DHPs)

Research on Chemical Intermediates, Journal Year: 2024, Volume and Issue: 50(4), P. 1713 - 1743

Published: March 8, 2024

Language: Английский

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Electrochemical C-H Halogenations of Enaminones and Electron-Rich Arenes with Sodium Halide (NaX) as Halogen Source for the Synthesis of 3-Halochromones and Haloarenes

The Journal of Organic Chemistry, Journal Year: 2021, Volume and Issue: 86(17), P. 12378 - 12385

Published: Aug. 16, 2021

Without employing an external oxidant, the simple synthesis of 3-halochromones and various halogenated electron-rich arenes has been realized with electrode oxidation by simplest sodium halide (NaX, X = Cl, Br, I) as halogen source. This electrochemical method is advantageous for mild room temperature operation, environmental friendliness well broad substrate scope in both C–H bond donor source components.

Language: Английский

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Four-component synthesis of 3-aminomethylated imidazoheterocycles in EtOH under catalyst-free, oxidant-free and mild conditions

Green Chemistry, Journal Year: 2021, Volume and Issue: 23(12), P. 4430 - 4434

Published: Jan. 1, 2021

The 3-aminomethylated imidazoheterocycles were efficiently synthesized in one-step via a four-component reaction of equimolar cheap and commercially available reactants at ambient temperature under catalyst-, oxidant-, base-free mild conditions.

Language: Английский

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Electrochemical Selenylative Carbannulation of Biaryl Ynones to Seleno-Dibenzocycloheptenones/Spiro[5.5]Trienones

The Journal of Organic Chemistry, Journal Year: 2021, Volume and Issue: 86(23), P. 17071 - 17081

Published: Nov. 22, 2021

Electrooxidative-induced synthesis of structurally diverse seleno-dibenzocyclohepten-5-ones and seleno-spiro[5.5]trienones by selenylative carbannulation biaryl ynones with diaryl diselenide has been developed. The switchable reactivity, intramolecular ortho-annulation or dearomative ipso-annulation, is directed the substituent present on ortho-aryl group aryl-ynone. prominent features this method include metal-free, external chemical oxidant-free conditions, readily accessible substrates.

Language: Английский

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Multicomponent Bifunctionalization of Methyl Ketones Enabled by Heterogeneous Catalysis and Solar Photocatalysis in Water

ACS Sustainable Chemistry & Engineering, Journal Year: 2021, Volume and Issue: 9(40), P. 13663 - 13671

Published: Sept. 29, 2021

Herein, a novel and green multicomponent transformation for the α-bifunctionalization of methyl ketones enabled by heterogeneous catalysis solar photocatalysis has been described. This reaction is performed in water under an air atmosphere, affording corresponding products moderate-to-good yield. Our shows successful combination photocatalysis, giving sustainable practical alternative modification ketone derivatives.

Language: Английский

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Visible light-enabled iron-catalyzed selenocyclization of N-methoxy-2-alkynylbenzamide

Molecular Catalysis, Journal Year: 2021, Volume and Issue: 515, P. 111881 - 111881

Published: Sept. 15, 2021

Language: Английский

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