Handbook of CH‐Functionalization,
Journal Year:
2022,
Volume and Issue:
unknown, P. 1 - 42
Published: Oct. 1, 2022
Abstract
This
article
is
intended
to
provide
a
concise
review
of
the
seminal
work
on
nickel‐catalyzed
direct
“sp
2
”
CH
bond
functionalizations,
with
particular
focus
trifluoromethylation,
thiolation,
and
selenylation.
The
current
mechanistic
hypotheses
were
described
for
deeper
understanding
that
should
aid
in
future
design
various
other
efficient
transformations.
We
anticipate
continued
research
this
area
help
extend
applications
late‐stage
functionalization
bioactive
molecules.
Chemical Reviews,
Journal Year:
2022,
Volume and Issue:
122(21), P. 16110 - 16293
Published: Sept. 16, 2022
In
the
present
review,
we
discuss
recent
progress
in
field
of
C–Z
bond
formation
reactions
(Z
=
S,
Se,
Te)
catalyzed
by
transition
metals.
Two
complementary
methodologies
are
considered─catalytic
cross-coupling
and
catalytic
addition
reactions.
The
development
advanced
systems
is
aimed
at
improved
catalyst
efficiency,
reduced
loading,
better
cost
environmental
concerns,
higher
selectivity
yields.
important
rise
research
efforts
sustainability
green
chemistry
areas
critically
assessed.
paramount
role
mechanistic
studies
a
new
generation
addressed,
key
achievements,
problems,
challenges
summarized
for
this
field.
Green Synthesis and Catalysis,
Journal Year:
2022,
Volume and Issue:
4(3), P. 226 - 230
Published: April 12, 2022
Using
visible
light
as
energy
to
form
free
radicals
has
important
synthetic
value.
A
novel
and
efficient
visible-light-mediated
strategy
been
developed
for
the
generation
of
thiobenzene
through
cerium-catalyzed
activation
disulfides.
Through
this
photochemical
reaction,
various
3-sulfenylated
quinoxalin-2(1H)-ones
can
be
conveniently
obtained
in
good
yields
with
functional
group
tolerance.
Our
transformation
provides
an
alternative
that
allows
rapid
access
C3
sulfenylated
a
sustainable
practical
manner.
Organic & Biomolecular Chemistry,
Journal Year:
2022,
Volume and Issue:
20(31), P. 6072 - 6177
Published: Jan. 1, 2022
Transition
metal
catalysed
C–S
bond
formation
from
unreactive
C–H
bonds
is
a
remarkable
tool
in
the
late-stage
functionalization
of
complex
molecules.
This
review
highlights
significant
advances
and
mechanistic
analyses
last
two
decades.
Organic & Biomolecular Chemistry,
Journal Year:
2024,
Volume and Issue:
22(32), P. 6617 - 6630
Published: Jan. 1, 2024
A
ubiquitous
copper(
ii
)-catalyzed
regioselective
ortho
C(sp
2
)–H
amination
of
arenes/heteroarenes
has
been
revealed
with
the
assistance
8-AIP
(8-aminoimidazo[1,2-
a
]pyridine)
as
an
efficacious
6,5-fused
bicyclic
removable
chelating
auxiliary.
Organic Chemistry Frontiers,
Journal Year:
2021,
Volume and Issue:
8(24), P. 6937 - 6949
Published: Jan. 1, 2021
A
site-specific
C6–H
chalcogenation
of
quinoxalin-2(1
H
)-ones
with
various
diselenides
and
dithiols
is
presented
by
employing
Selectfluor
reagent
as
an
oxidant.
The Journal of Organic Chemistry,
Journal Year:
2021,
Volume and Issue:
86(21), P. 15185 - 15202
Published: Oct. 26, 2021
A
general
protocol
has
been
developed
for
the
construction
of
carbon-heteroatom
(C-N,
C-Cl,
C-O,
C-S,
and
C-Se)
bonds
using
bench
stable,
earth-abundant,
environmentally
benign
copper
catalyst.
Only
oxygen
is
sufficient
to
regenerate
Control
experiments
suggested
that
proto-demetalation
step
reversible.
Depending
on
coupling
partner,
reaction
follows
either
disproportionation
or
radical
pathways
complete
catalytic
cycle.
The
synthetic
utility
demonstrated
via
various
functional
group
transformations.
Chinese Journal of Organic Chemistry,
Journal Year:
2023,
Volume and Issue:
43(11), P. 3761 - 3761
Published: Jan. 1, 2023
Sulfur-containing
compounds
are
widely
found
in
natural
products,
pharmaceuticals,
pesticides,
and
materials,
possessing
a
variety
of
biological
activities
or
unique
functions.C-S
coupling
reaction
is
an
important
method
for
the
synthesis
sulfur-containing
one
hot
spots
field
organic
synthesis.With
in-depth
development
catalysts
continuous
expansion
partners,
large
number
C-S
reactions
have
emerged
recent
years,
which
greatly
facilitate
compounds.Aryl
halides
main
kind
substrates
compounds.C-S
aryl
partners
can
efficiently
afford
compounds,
such
as
thiophenols,
thioethers,
disulfides
sulfones
different
well-designed
systems.In
this
review,
with
reviewed
according
to
types
(palladium,
copper,
nickel,
others).The
mechanisms
representative
briefly
described
compared.In
addition,
brief
analysis
current
situations
limitations
given,
prospect
future
put
forward.
RSC Advances,
Journal Year:
2023,
Volume and Issue:
13(9), P. 6191 - 6198
Published: Jan. 1, 2023
A
rhodium-catalysed,
regioselective
synthetic
methodology
for
selenylation
and
sulfenylation
of
3-phenyl
quinoxolinones
has
been
developed
through
N-directed
C-H
activation
in
the
presence
silver
triflimide,
carbonate
using
dichalcogenides
'on
water'.
The
proven
to
be
efficient,
green.
Using
this
method,
a
range
selenylations
sulfenylations
substrates
carried
out
good
excellent
yields.
Further,
late-stage
functionalisation
produced
potential
anti-tumour,
anti-fungal
anti-bacterial
agents
making
these
compounds
drug
candidates.
Chinese Journal of Chemistry,
Journal Year:
2023,
Volume and Issue:
42(9), P. 985 - 989
Published: Dec. 26, 2023
Comprehensive
Summary
A
Ru(II)‐catalyzed
ortho
allylation
reaction
of
N
‐aryl‐7‐azaindole
with
readily
available
2‐methylidene
cyclic
carbonate
has
been
developed.
This
is
an
effective
pathway
for
synthesizing
7‐azaindole
derivatives
a
wide
scope
substrates
and
high
yields.
In
addition,
the
method
can
be
extended
to
other
heterocyclic
compounds
several
carbonates,
highlighting
practicality
this
strategy
synthesis.
Asian Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
13(5)
Published: March 21, 2024
Abstract
A
direct
selenylation
of
N
‐arylsulfonamides
and
anilides
using
environmentally
friendly
readily
available
copper
promoted
assisted
by
amide
is
presented.
This
method
provided
convenient
access
for
various
reactions,
demonstrating
a
wide
range
substrates
strong
tolerance
to
functional
groups.
According
the
selection
reaction
substrates,
products
can
be
isolated
obtain
regioselectivity
ortho
‐,
para
or
unprecedented
,
‐diselenylation
products.
Such
transformation
was
elucidated
proposed
copper‐promoted
amide‐assisted
radical
mechanism.
