SynOpen,
Journal Year:
2021,
Volume and Issue:
05(01), P. 91 - 99
Published: Jan. 1, 2021
Abstract
A
highly
efficient
and
eco-friendly
method
has
been
developed
for
the
synthesis
of
allyl
sulfones
using
Morita–Baylis–Hillman
(MBH)
adducts
thiosulfonates
under
mild
conditions.
The
Cs2CO3-promoted
radical
sulfonylation
provided
a
series
in
good
to
high
yields
with
stereoselectivities.
wide
variety
MBH
bromides/acetates
as
well
were
tolerated
reliable
scaled-up
synthesis.
plausible
mechanism
is
proposed
rationalize
sulfonylation.
Journal of the American Chemical Society,
Journal Year:
2021,
Volume and Issue:
143(50), P. 21340 - 21349
Published: Dec. 8, 2021
Charge
separation
plays
a
crucial
role
in
regulating
photochemical
properties
and
therefore
warrants
consideration
designing
photocatalysts.
Metal-organic
frameworks
(MOFs)
are
emerging
as
promising
candidates
for
heterogeneous
photocatalysis
due
to
their
structural
designability
tunability
of
photon
absorption.
Herein,
we
report
the
design
pyrazole-benzothiadiazole-pyrazole
organic
molecule
bearing
donor-acceptor-donor
conjugated
π-system
fast
charge
separation.
Further
attempts
integrate
such
photosensitizer
into
MOFs
afford
more
effective
photocatalyst
(JNU-204).
Under
visible-light
irradiation,
three
aerobic
oxidation
reactions
involving
different
oxygenation
pathways
were
achieved
on
JNU-204.
Recycling
experiments
conducted
demonstrate
stability
reusability
JNU-204
robust
photocatalyst.
Furthermore,
illustrate
its
applications
facile
synthesis
pyrrolo[2,1-a]isoquinoline-containing
heterocycles,
core
skeletons
family
marine
natural
products.
is
an
exemplary
MOF
platform
with
good
absorption,
suitable
band
gap,
separation,
extraordinary
chemical
proceeding
under
irradiation.
ACS Sustainable Chemistry & Engineering,
Journal Year:
2024,
Volume and Issue:
12(12), P. 5046 - 5051
Published: March 14, 2024
A
sustainable
method
for
the
construction
of
valuable
β-keto
sulfones
lies
in
reaction
between
vinyl
azides
and
alkyl
sulfonyl
radical
generated
from
low-cost
comparatively
steady
bulk
chemical
dimethyl
sulfoxide
(DMSO)
that
has
been
developed.
This
strategy
features
mild
economical
conditions
using
inexpensive
NiCl2
as
catalyst
H2O2
green
oxidant.
The
conversion
occurs
through
a
sequence
ordered
processes
consisting
addition,
denitrogen,
hydrogen
abstraction,
hydrolysis.
Mechanistic
studies
indicate
sulfinic
acid
produced
DMSO
plays
an
essential
role
reduction
Ni(III).
sensitivity
assessment
gram-scale
experiments
proceed
smoothly
to
demonstrate
robustness
practicality
this
protocol.
Organic Chemistry Frontiers,
Journal Year:
2021,
Volume and Issue:
8(19), P. 5403 - 5409
Published: Jan. 1, 2021
A
visible-light
photoredox-catalyzed
four
component
reaction
of
quinoxalin-2(1
H
)-ones,
alkenes,
aryldiazonium,
and
sodium
metabisulfite
leading
to
sulfone-containing
)-ones
has
been
developed.
ACS Omega,
Journal Year:
2022,
Volume and Issue:
7(44), P. 39531 - 39561
Published: Oct. 27, 2022
Sulfonyl
hydrazides
are
viewed
as
alternatives
to
sulfinic
acids
and
their
salts
or
sulfonyl
halides,
which
broadly
used
in
organic
synthesis
work
active
pharmaceutical
substances.
Generally,
considered
good
building
blocks
show
powerful
value
a
diverse
range
of
reactions
construct
C–S
bonds
C–C
bonds,
even
C–N
sulfur,
carbon,
nitrogen
sources,
respectively.
As
profound
synthetic
tool,
the
electrosynthesis
method
was
recently
achieve
efficient
green
applications
hydrazides.
Interestingly,
many
unique
novel
electrochemical
syntheses
using
radical
precursors
have
been
developed,
including
cascade
reactions,
functionalization
heterocycles,
well
continuous
flow
combining
with
since
2017.
Accordingly,
it
is
necessary
specifically
summarize
recent
developments
only
more
deeply
understand
better
design
reactions.
Herein,
research
2017
reviewed
detail
based
on
chemical
structures
products
reaction
mechanisms.
Advanced Synthesis & Catalysis,
Journal Year:
2023,
Volume and Issue:
365(14), P. 2310 - 2331
Published: June 24, 2023
Abstract
Alkenes
are
valuable
feedstocks
in
organic
synthesis.
Selenium
or
sulfur‐containing
coumpounds
with
a
neighboring
functional
group
can
be
easily
prepared
by
direct
difunctionalization
of
alkenes
via
three‐component
reactions.
It
will
reduce
the
number
steps
and
waste
generation,
form
complicated
molecules
from
simple
starting
materials.
Herein,
recent
developments
(2013–2022)
have
been
summarized
two
categories:
(1)
selenylation
seleniranium
intermediates
Se‐centered
radicals;
(2)
thiolation
more
diverse
mechanisms
products
Reactions
electron‐rich
arenes,
alcohols,
water,
acids,
NaN
3
,
amines,
KSCN,
sulfamides,
TMSNCS,
TMSN
Et
N
⋅
3HF,
SOCl
2
HCl,
NFSI,
t
BuONO,
pyridinium
salts,
BuOOH,
ArN
BF
4
CO
CO,
O
CF
SO
Cl,
R
P(O)−H,
(RO)
P(O)SH,
P(O)OH
et
al
discussed.
We
hope
this
review
do
help
for
future
research
area.
Organic & Biomolecular Chemistry,
Journal Year:
2022,
Volume and Issue:
20(21), P. 4331 - 4337
Published: Jan. 1, 2022
A
unique
cycloannulation
of
(
E
)-β-iodovinyl
sulfones
with
1-aminopyridinium
iodide/
N
-tosylpyridinium
imide
followed
by
detosylation
is
realized
to
access
2-substituted-pyrazolo[1,5-
a
]pyridines
and
their
3-sulfonyl
analogues
in
good
high
yields.
Organic Letters,
Journal Year:
2022,
Volume and Issue:
24(36), P. 6653 - 6657
Published: Sept. 1, 2022
Switchable
in
situ
SO2
capture
and
CF3
migration
of
enol
triflates
with
peroxyl
compounds
under
iron
catalysis
are
presented.
By
regulating
the
structure
peroxides,
a
variety
keto-functionalized
dialkyl
sulfones
α-trifluoromethyl
ketones
were
selectively
synthesized
good
yields
mild
conditions.
Organic Chemistry Frontiers,
Journal Year:
2023,
Volume and Issue:
10(20), P. 5190 - 5197
Published: Jan. 1, 2023
An
efficient
and
rapid
iron-catalyzed
oxosulfonylation
of
alkynes
with
small-ring
compounds
Na
2
S
O
5
for
the
synthesis
β
-keto
sulfones
has
been
developed.
Chinese Journal of Chemistry,
Journal Year:
2024,
Volume and Issue:
42(12), P. 1367 - 1372
Published: Feb. 23, 2024
Comprehensive
Summary
The
selective
oxidative
sulfonylation
of
alkenes
with
selenium
sulfonate
depended
on
the
reaction
conditions.
electrochemical
C—H
proceeded
smoothly
to
afford
(
E
)‐vinyl
sulfones
good
selectivity
in
an
undivided
cell
without
external
oxidant.
While
aerobic
trifunctionalization
occurred
presence
KI
air,
which
provides
β
‐keto
selenosulfones
via
formation
C—O,
C—S,
and
C—Se
bonds
one‐pot.
Following
control
experiments,
a
plausible
mechanism
is
proposed
rationalize
experimental
results.
