Access to Dibenzo[c,e]azonines by Iron-Catalyzed Alkyne–Carbonyl Metathesis DOI
Paul Richardson, Johnny W. Lee

Synfacts, Journal Year: 2022, Volume and Issue: 18(04), P. 0358 - 0358

Published: March 18, 2022

Key words iron catalysis - alkynes dibenzoazonines cyclization metathesis

Language: Английский

Synthesis of novel benzopyrimido[4,5-d]azoninone analogs catalyzed by biosynthesized Ag-TiO2 core/shell magnetic nanocatalyst and assessment of their antioxidant activity DOI Creative Commons
Mohamed M. Hammouda, K. Shalabi, Abdulaziz A. Alanazi

et al.

RSC Advances, Journal Year: 2023, Volume and Issue: 13(46), P. 32532 - 32546

Published: Jan. 1, 2023

A novel series of benzopyrimido[4,5- d ]azoninones were synthesized using a Ag-TiO 2 core/shell magnetic nanocatalyst, characterized by spectroscopic analyses and assessed as antioxidant agents DPPH phosphomolybdate assays.

Language: Английский

Citations

11
A Catalytic Intramolecular Aldehyde–Alkyne Metathesis Approach to Azepino[1,2‐a]indoles DOI

U. Deka,

Arup Jyoti Das,

Swapnil Kumar Nath

et al.

Advanced Synthesis & Catalysis, Journal Year: 2024, Volume and Issue: 366(21), P. 4452 - 4461

Published: July 23, 2024

Abstract Reported herein is a method for the construction of azepino[1,2‐ ]indoles via an intramolecular aldehyde–alkyne metathesis 1‐(5‐aryl‐4‐pentynyl)indole‐2‐carbaldehydes. This Sc(OTf) 3 ‐catalyzed reaction has several remarkable features, such as ready accessibility starting materials, broad substrate scope, operational simplicity, and high yields. The practicality process synthetic potential products were demonstrated with upscaling experiment downstream derivatizations obtained products. We have also extended this methodology to synthesize 6,7‐dihydropyrido[1,2‐ ]indole derivative.

Language: Английский

Citations

3
Sc(OTf)3-catalyzed alkyne-carbonyl metathesis-initiated cyclization for accessing naphtho[2,1-b]furan-1-ones under microwave heating DOI

Wei-Le Li,

Bao-Yang Liu,

Chunmei Li

et al.

Tetrahedron Letters, Journal Year: 2024, Volume and Issue: 138, P. 154962 - 154962

Published: Feb. 16, 2024

Language: Английский

Citations

2
Recent Advances on the Synthesis of Nine-Membered N-Heterocycles DOI Open Access

Xiaoting Qin,

Ning Zou,

Cai‐Mei Nong

et al.

Chinese Journal of Organic Chemistry, Journal Year: 2023, Volume and Issue: 43(1), P. 130 - 130

Published: Jan. 1, 2023

Nine-membered N-heterocycle scaffolds are widely found in natural products and biologically active molecules.The rigid structure of the medium-sized ring plays important roles regulation their biological pharmacological activities.Therefore, nine-membered is one most attractive compounds.Because increasing entropy extension skeleton, synthesis N-heterocycles still difficult; especially effective control substituent stereoselectivity for greatest challenging topics This review summarizes novel synthetic strategies applications pharmaceutically molecules containing scaffold recent years.Keywords N-

Language: Английский

Citations

6
The Anticorrosive Efficacy of Newly Synthesized Pyrido-bis(benzo[b]azoninone) Analogs on Carbon Steel Under Sweet Corrosive Environments: A Combined Empirical and Theoretical Approaches DOI
K. Shalabi, Hany M. Abd El‐Lateef, Mohamed M. Hammouda

et al.

Colloids and Surfaces A Physicochemical and Engineering Aspects, Journal Year: 2024, Volume and Issue: 702, P. 134958 - 134958

Published: July 30, 2024

Language: Английский

Citations

1
Phase-transfer catalyzed Michael/ammonolysis cascade reactions of enaminones and olefinic azlactones: a new approach to structurally diverse quinoline-2,5-diones DOI
Lin Chen, Liang Wei

Organic & Biomolecular Chemistry, Journal Year: 2022, Volume and Issue: 20(15), P. 3201 - 3210

Published: Jan. 1, 2022

Michael/ammonolysis cascade reactions between cyclohexane-1,3-dione-derived enaminones and olefinic azlactones via phase-transfer catalysis have been developed. This method provides rapid access to a suite of architecturally complex diverse quinoline-2,5-diones bearing secondary amide group at the C-3 position in moderate excellent yields (53-94%) with diastereoselectivities (>99 : 1 dr most cases). The achievement preparative-scale reaction product derivatization that can be obtained highlight application potential this protocol both academic industrial settings. An investigation mechanism implies tetrabutylammonium hydroxide may actual catalyst during reaction.

Language: Английский

Citations

7
Silica Sulphuric Acid Catalyzed Intra‐molecular Alkyne Carbonyl Metathesis (ACM): A Rapid Access to 2H‐ Chromenes DOI
Mahender Khatravath,

Rohit Maurya,

Vikash Kumar

et al.

Asian Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: July 11, 2024

Abstract A highly efficient, convenient and ecofriendly approach to access functionalized 2H ‐chromenes via intramolecular aldehyde alkyne metathesis reaction was established starting from readily accessible alkyne‐tethered 2‐((3‐phenylprop‐2‐yn‐1‐yl) oxy)benzaldehydes catalyzed by silica sulfuric acid (SiO 2 ‐OSO 3 H, SSA) coupled with microwave irradiation. This well tolerated for various substituents including different functional groups furnished the desired H ‐chromene derivatives in good excellent yields a very short time. systematic study of conventional heating irradiation performed demonstrate advantages microwave‐assisted condition terms high yield shorter

Language: Английский

Citations

1
Iron-Catalyzed Synthesis of 13-Aryl-13H-indeno[1,2-l]phenanthrene via Double Annulations of 2-Alkynyl Biaryls DOI

Rupsa Chanda,

Tubai Ghosh, Umasish Jana

et al.

The Journal of Organic Chemistry, Journal Year: 2022, Volume and Issue: 88(1), P. 658 - 664

Published: Dec. 20, 2022

An Fe(III)-catalyzed expedient synthesis of 13-aryl-13H-indeno[1,2-l]phenanthrene is described by a double annulations 2-alkynyl biaryls, initiated the activation acetal. This strategy provides simple, efficient and regioselective varieties indenophenanthrene derivatives from easily available starting materials under mild conditions in high to excellent yields. A plausible reaction mechanism proposed.

Language: Английский

Citations

2
Access to Dibenzo[c,e]azonines by Iron-Catalyzed Alkyne–Carbonyl Metathesis DOI
Paul Richardson, Johnny W. Lee

Synfacts, Journal Year: 2022, Volume and Issue: 18(04), P. 0358 - 0358

Published: March 18, 2022

Key words iron catalysis - alkynes dibenzoazonines cyclization metathesis

Language: Английский

Citations

0