Organic Letters, Journal Year: 2023, Volume and Issue: 25(9), P. 1476 - 1480
Published: March 1, 2023
A ruthenium(II)-catalyzed one-pot synthesis of highly substituted 1,2-dihydropyridines (DHPs) via a three-component reaction system has been realized. The is conducted using simple Ru(II) catalyst without the addition specific ligands. catalytic exhibits good functionality tolerance with wide range starting materials. DHPs obtained can be easily converted into tetrahydropyridines and azabicyclo[4.2.0]octa-4,7-dienes by subsequent reduction or [2 + 2] cycloaddition reaction.
Language: Английский