The Journal of Organic Chemistry,
Journal Year:
2022,
Volume and Issue:
87(10), P. 6832 - 6837
Published: May 2, 2022
In
this
computational
study,
we
provide
a
detailed
analysis
of
the
underlying
reaction
mechanism
and
show
that
singlet
carbene
is
initially
formed.
Depending
on
pKA
alcohol,
can
engage
in
direct
protonation
or
enol
formation
to
yield
O-H
functionalization
product.
On
contrary,
propargylic
alcohols
take
up
dual
role
form
complex
with
intermediate
leads
facile
cyclopropenation
reactions.
Chemical Reviews,
Journal Year:
2024,
Volume and Issue:
124(11), P. 7214 - 7261
Published: May 16, 2024
In
recent
years,
visible
light-induced
reactions
of
diazo
compounds
have
attracted
increasing
attention
in
organic
synthesis,
leading
to
improvement
existing
reactions,
as
well
the
discovery
unprecedented
transformations.
Thus,
photochemical
or
photocatalytic
generation
both
carbenes
and
radicals
provide
milder
tools
toward
these
key
intermediates
for
many
valuable
However,
vast
majority
transformations
represent
new
reactivity
modes
compounds,
which
are
achieved
by
decomposition
photoredox
catalysis.
particular,
use
a
redox-active
photocatalysts
opens
avenue
plethora
radical
reactions.
The
application
methods
led
inaccessible
classical
associated
with
metal
carbenes.
most
cases,
act
sources
but
can
also
serve
acceptors.
Importantly,
described
processes
operate
under
mild,
practical
conditions.
This
Review
describes
this
subfield
compound
chemistry,
particularly
focusing
on
advancements.
Chemical Communications,
Journal Year:
2023,
Volume and Issue:
59(48), P. 7346 - 7360
Published: Jan. 1, 2023
This
article
discusses
the
photochemistry
of
several
diazo
compounds
undergoing
visible
light-mediated
photolysis
to
generate
free
carbenes
(or
other
highly
reactive
intermediates),
which
can
be
sequentially
trapped
by
different
reacting
partners.
Chinese Journal of Organic Chemistry,
Journal Year:
2021,
Volume and Issue:
41(12), P. 4565 - 4565
Published: Jan. 1, 2021
Carbene
is
one
of
the
most
important
synthetic
intermediates
in
organic
synthesis.In
past
few
decades,
transition-metal
catalyzed
carbene
transfer
reactions
have
made
remarkable
development.Recently,
visible
light-promoted
transformation
diazo
compounds
through
formation
free
as
key
intermediate
begun
to
rise.The
reaction
only
need
light
sole
energy
source
which
meets
concept
green
chemistry.Since
pioneering
works
developed
by
groups
Diaves
and
Zhou,
photo-promoted
has
attracted
more
attentions.On
basis
previous
work,
latest
progress
this
field
further
improved,
mainly
focuses
on
recent
new
under
irradiation
contributions
reported
from
Chinese
research
group.The
future
development
direction,
well
challenges
prospected.
Green Chemistry,
Journal Year:
2022,
Volume and Issue:
24(12), P. 4915 - 4920
Published: Jan. 1, 2022
A
convenient
and
eco-friendly
visible-light
promoted
multicomponent
protocol
has
been
developed
for
the
synthesis
of
S
-alkyl
phosphorothioates
by
using
elemental
sulfur
as
cheap
odorless
source.
ACS Catalysis,
Journal Year:
2022,
Volume and Issue:
12(9), P. 5510 - 5516
Published: April 25, 2022
We
developed
an
efficient
visible-light-mediated
formal
carbene
insertion
reaction
of
1,3-diketones
with
diazoesters
for
the
construction
enantioenriched
1,4-dicarbonyl
compounds
a
quaternary
carbon
center.
Combining
visible
light
and
Brønsted
acid
catalyst,
chiral
were
achieved
in
good
yields
high
enantioselectivities
by
photochemical
transfer
protocol.
European Journal of Organic Chemistry,
Journal Year:
2022,
Volume and Issue:
2022(44)
Published: Oct. 21, 2022
Abstract
Cyclopropanes
are
one
of
the
most
important
strained
rings
existing
in
various
pharmaceutical
products
and
secondary
metabolites.
They
also
widely
used
total
synthesis
natural
products,
medicinal
chemistry,
materials
science.
In
past
years,
photochemical
cyclopropanation
has
been
gradually
developed
as
a
robust
attractive
synthetic
method
to
prepare
diverse
cyclopropane
backbones.
this
review,
we
summarize
recent
advances
visible
light‐mediated
synthesis,
especially
using
carbene
transfer
strategy
photocatalytic
radical
reactions.
