Metal- and base-free regioselective cascade sulfonylation-cyclization of 1,5-dienes via the insertion of sulfur dioxide: access to pyrrolinones DOI
Ran Ding,

Xue-Feng Tang,

Yu-Hang Deng

et al.

New Journal of Chemistry, Journal Year: 2022, Volume and Issue: 46(27), P. 12901 - 12904

Published: Jan. 1, 2022

A metal- and base-free regioselective cascade sulfonylation–cyclization reaction of linear substrates, 1,5-dienes, has been developed to synthesize sulfonylated pyrrolinones.

Language: Английский

Visible-Light-Induced Cascade Cyclization of N-Propargyl Aromatic Amines and Acyl Oxime Esters: Rapid Access to 3-Acylated Quinolines DOI
Man Zhang,

Sixin Wu,

Lei Wang

et al.

The Journal of Organic Chemistry, Journal Year: 2022, Volume and Issue: 87(15), P. 10277 - 10284

Published: July 6, 2022

Visible-light-induced radical cascade acylation/cyclization/aromatization of N-propargyl aromatic amines and acyl oxime esters for the construction 3-acylated quinolines is developed. This approach uses as precursor radicals well acylation reagents, Eosin Y photocatalyst, acetonitrile solvent, providing a convenient route toward via C-C bond cleavage esters.

Language: Английский

Citations

9
Copper(I)‐Catalyzed Regioselective Tandem Cyanoalkylative Cyclization of 1,5‐Dienes with Cyclobutanone Oxime Esters DOI
Panpan Wang, Yuting Leng, Yangjie Wu

et al.

European Journal of Organic Chemistry, Journal Year: 2022, Volume and Issue: 2022(45)

Published: Oct. 19, 2022

Abstract An effective strategy for construction of 1,5‐dihydro‐2H‐pyrrol‐2‐one scaffolds by a cascade 1,5‐dienes with cyclobutanone oxime esters was developed. The reaction proceeded through radical addition, 5‐endo cyclization, and subsequent deprotonation, in which two new C−C bonds were formed. This protocol features excellent regioselectivity low‐cost catalyst, as well broad substrate scope, are expected to promote its potential applications pharmacy synthetic chemistry.

Language: Английский

Citations

8
NHC-Catalyzed Tandem Reaction: A Strategy for the Synthesis of 2-Pyrrolidinone-Functionalized Phenanthridines DOI
Nengneng Zhou, Lei Wang,

Fangli Zhao

et al.

The Journal of Organic Chemistry, Journal Year: 2023, Volume and Issue: 88(23), P. 16556 - 16565

Published: Nov. 16, 2023

Herein, an N-heterocyclic carbene (NHC)-catalyzed tandem cyclization/addition/cyclization reaction of 2-isocyanobiaryls and α-bromo-N-cinnamylamides for the synthesis 2-pyrrolidinone-functionalized phenanthridines is developed. This protocol features a radical cascade process, broad substrate scope, good functional group compatibility under metal- oxidant-free conditions.

Language: Английский

Citations

4
Divergent cyanoalkylation/cyanoalkylsulfonylation of enamides under organophotoredox catalytic conditions DOI

Durga Golagani,

Abuthayir Mohamathu Ghouse,

Sriram Ajmeera

et al.

Organic & Biomolecular Chemistry, Journal Year: 2022, Volume and Issue: 20(44), P. 8599 - 8604

Published: Jan. 1, 2022

An organophotoredox catalyzed divergent cyanoalkylation/cyanoalkylsulfonylation of enamides is described.

Language: Английский

Citations

7
Metal- and base-free regioselective cascade sulfonylation-cyclization of 1,5-dienes via the insertion of sulfur dioxide: access to pyrrolinones DOI
Ran Ding,

Xue-Feng Tang,

Yu-Hang Deng

et al.

New Journal of Chemistry, Journal Year: 2022, Volume and Issue: 46(27), P. 12901 - 12904

Published: Jan. 1, 2022

A metal- and base-free regioselective cascade sulfonylation–cyclization reaction of linear substrates, 1,5-dienes, has been developed to synthesize sulfonylated pyrrolinones.

Language: Английский

Citations

6