ACS symposium series,
Journal Year:
2024,
Volume and Issue:
unknown, P. 257 - 285
Published: May 14, 2024
Copper
is
less
expensive
and
has
more
readily
available
resources
than
many
other
transition
metals,
making
it
accessible.
Loading
nano-sized
copper
particles
on
the
surfaces
of
support
materials
or
obtaining
nanoparticles
based
reduction
processes
just
metal
using
them
as
nanocatalysts
an
interesting
research
area.
Copper-based
produced
in
various
ways
have
been
effectively
employed
a
wide
range
organic
chemical
processes.
We
will
demonstrate
how
copper-based
are
used
chemistry
such
oxidation,
reduction,
click
chemistry,
Ullman-type
cross-coupling
reactions,
cyclization
reactions.
To
stay
current
work
this
field,
we
concentrated
providing
most
recent
scientific
breakthroughs
section,
which
include
articles
published
between
2016
2023.
The
number
obtained,
well
significant
recommendations,
were
gathered
from
selected
incorporated
into
chapter.
Chemical Society Reviews,
Journal Year:
2022,
Volume and Issue:
51(18), P. 7810 - 7882
Published: Jan. 1, 2022
Although
C–H
functionalization
is
one
of
the
simplest
reactions,
it
requires
use
highly
active
and
selective
catalysts.
Recently,
C–H-active
transformations
using
porous
materials
such
as
crystalline
metal-organic
frameworks
(MOFs)
covalent-organic
(COFs)
well
amorphous
porous-organic
polymers
(POPs)
new
emerging
heterogeneous
catalysts
have
attracted
significant
attention
due
to
their
promising
activity
potential
material
tunability.
These
solids
offer
exceptional
structural
uniformity,
facile
tunability
permanent
porosity.
In
addition,
tuning
catalytic
selectivity
these
can
be
achieved
through
engineering
site
microenvironments,
metal
node
substitution,
linker
changes,
node/linker
functionalization,
pore
modification.
The
present
review
provides
an
overview
current
state
art
on
MOFs,
COFs
POPs
advanced
for
various
bond
activation
providing
details
about
chemo-,
regio-,
stereo-selectivity
control,
comparing
performance
with
that
other
catalysts,
triggering
additional
research
by
showing
limitations
challenges
in
this
area,
a
perspective
future
developments.
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(5), P. 2599 - 2599
Published: Feb. 23, 2024
N-heterocyclic
carbene
(NHC)
silver(I)
and
gold(I)
complexes
have
found
different
applications
in
various
research
fields,
as
medicinal
chemistry
for
their
antiproliferative,
anticancer,
antibacterial
activity,
innovative
effective
catalysts.
The
possibility
of
modulating
the
physicochemical
properties,
by
acting
on
ligands
substituents,
makes
them
versatile
tools
development
novel
metal-based
compounds,
mostly
anticancer
compounds.
As
it
is
known,
chemotherapy
commonly
adopted
clinical
treatment
cancers,
even
though
its
efficacy
hampered
several
factors.
Thus,
more
less
toxic
drugs
still
an
urgent
need.
Herein,
we
reported
synthesis
characterization
new
stabilized
caffeine-derived
NHC
ligands,
together
with
biological
catalytic
activities.
Our
data
highlight
interesting
properties
this
series
catalysts
A3-coupling
hydroamination
reactions
promising
anti-inflammatory,
antioxidant
agents.
ability
these
regulating
pathological
aspects,
often
co-promoting
causes,
cancer
ideal
leads
to
be
further
structurally
functionalized
investigated.
The Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
89(11), P. 8220 - 8229
Published: May 16, 2024
In
this
work,
a
practical
copper-catalyzed
multicomponent
coupling
reaction
of
primary
aromatic
amines,
rongalite,
and
alkynes
for
the
direct
synthesis
N-aryl
propargylamines
has
been
developed.
This
method
could
overcome
substrate
limitation
in
A3
reactions
formaldehyde,
alkynes.
Mechanistic
studies
revealed
that
rongalite
acts
as
not
only
active
C1
unit
but
also
accelerator
to
activate
situ-generated
N-arylmethanimines
with
is
highly
efficient
features
broad
scope,
well
utility
scale-up
converting
corresponding
product
into
useful
heterocyclic
skeletons.
ChemistryOpen,
Journal Year:
2023,
Volume and Issue:
12(4)
Published: Jan. 31, 2023
Abstract
The
Ugi
reaction,
a
multicomponent
allows
diversity‐oriented
synthesis
Its
importance
is
recognized
by
an
exponential
increase
in
the
publications
utilizing
post‐Ugi
transformations
as
strategy
to
build
complex
molecules
via
simple
and
sustainable
processes
recent
literature.
A
second
concept,
alkyne
activation
through
metal‐,
acid‐,
iodine‐catalysis
base‐mediated
transformations,
also
leads
wonderful
short
efficient
synthetic
routes.
Combination
of
these
two
approaches
application
alkyne‐containing
component
reaction
brings
benefits
both
protocols
into
one
sequence.
propargyl
amines
come
obvious
choice
this
context
they
work
wonderfully
amine
while
has
potential
generate
biologically
interesting
carbo‐
hetero‐cyclic
systems.
Thus,
can
compare
adduct
with
pupa
which
inherent
property
metamorphosis
molecules.
In
review,
discussed
focus
on
transformations.
Organic & Biomolecular Chemistry,
Journal Year:
2022,
Volume and Issue:
20(24), P. 4933 - 4941
Published: Jan. 1, 2022
The
chemoselective
formation
of
five-membered
propargylic
cyclic
imines
and
the
subsequent
transformation
to
amines
via
(3
+
2)-cycloaddition
donor–acceptor
cyclopropanes
with
alkynylnitriles
mediated
by
BF
3
·OEt
2
has
been
documented.
