Synthesis,
Journal Year:
2024,
Volume and Issue:
56(09), P. 1415 - 1421
Published: Jan. 17, 2024
Abstract
An
environmentally
friendly
iodine-promoted
disproportionate
coupling
reaction
of
arylsulfonyl
hydrazides
is
reported.
This
strategy
can
synthesize
thiosulfonates
with
medium
to
excellent
yields,
and
features
a
green
system,
wide
applicability
substrates,
easy
availability
raw
materials.
The
preliminary
mechanistic
study
reveals
that
iodine
plays
an
important
role
in
the
radical
process.
Angewandte Chemie,
Journal Year:
2024,
Volume and Issue:
136(8)
Published: Jan. 5, 2024
Abstract
A
mild
photoredox
catalyzed
construction
of
sulfides,
disulfides,
selenides,
sulfoxides
and
sulfones
from
unstrained
ketone
precursors
is
introduced.
Combination
this
deacylative
process
with
S
N
2
or
coupling
reactions
provides
novel
convenient
modular
strategies
toward
unsymmetrical
symmetric
disulfides.
Reactivity
studies
favor
a
bromine
radical
that
initiates
HAT
(Hydrogen
Atom
Transfer)
the
aminal
intermediate
resulting
in
expulsion
C‐centered
intercepted
to
make
C−S
C−Se
bonds.
Gram
scale
reactions,
broad
substrate
scope
tolerance
towards
various
functional
groups
render
method
appealing
for
future
applications
synthesis
organosulfur
selenium
complexes.
Synthesis,
Journal Year:
2024,
Volume and Issue:
56(09), P. 1415 - 1421
Published: Jan. 17, 2024
Abstract
An
environmentally
friendly
iodine-promoted
disproportionate
coupling
reaction
of
arylsulfonyl
hydrazides
is
reported.
This
strategy
can
synthesize
thiosulfonates
with
medium
to
excellent
yields,
and
features
a
green
system,
wide
applicability
substrates,
easy
availability
raw
materials.
The
preliminary
mechanistic
study
reveals
that
iodine
plays
an
important
role
in
the
radical
process.
