Functional‐Nanochannel‐Based Artificial Postsynaptic Membrane for Neural Signal Transduction

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 9, 2024

Abstract Biological‐machine interface (BMI) devices represent a significant step toward adaptive and cognitive technologies. However, current BMI emphasize the analysis of electrophysiology often overlook chemical information neurotransmitters in process signaling between neurons. To bridge this gap, light‐gated artificial postsynaptic membrane (APM) is introduced, capable reading dopamine (DA) released from rat pheochromocytoma cells regulate neural signal transmission. Like biological membrane, APM porous functionalized by DA‐specific aptamers azobenzene (Azo) molecules different regions. Azo act as light‐responsive trigger that controls DA release, while capture DA, which converts its concentration into an ionic signal. By light‐enhanced responses to exocytosis (PC12) cells, confirms ability communicate with systems, lays foundation for developing biological‐machine interaction systems more advanced functionalities.

Language: Английский

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Light-Driven Ionic and Molecular Transport through Atomically Thin Single Nanopores in MoS₂/WS₂ Heterobilayers

ACS Nano, Journal Year: 2024, Volume and Issue: 18(35), P. 24581 - 24590

Published: Aug. 13, 2024

Nanofluidic ionic and molecular transport through atomically thin nanopore membranes attracts broad research interest from both scientific industrial communities for environmental, healthcare, energy-related technologies. To mimic the biological ion pumping functions, recently, light-induced quantum effect-facilitated charge separation in heterogeneous 2D-material assemblies is proposed as fourth type of driving force to achieve active noninvasive species synthetic membrane materials. However, date, engineering versatile van der Waals heterostructures into 2D remains largely unexplored. Herein, we fabricate single nanopores heterobilayer transition metal dichalcogenide with helium beam irradiation demonstrate light-driven translocation phenomena nanopores. Experimental simulation results further elucidate mechanism photoinduced near-pore electric potential difference due II band alignment semiconducting WS

Language: Английский

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Olfactory-Inspired Separation-Sensing Nanochannel-Based Electronics for Wireless Sweat Monitoring

ACS Nano, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 14, 2025

Human sweat has the potential to be sufficiently utilized for noninvasive monitoring. Given complexity of secretion, sensitivity and selectivity monitoring should further improved. Here, we developed an olfactory-inspired separation-sensing nanochannel-based electronic sensitive selective monitoring, which was simultaneously endowed with interferent separation target detection performances. The special strategy imparts functional composite membranes a high 113 mV dec–1 potassium detection. excellent mechanical properties conformability Kevlar aramid nanofiber layer bring well-wearing performances realize continuous wireless recognition between molecules ions is proved at molecular level in detail article. replacement proves universality performance enhancement intricate biofluid analysis systems.

Language: Английский

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Hammerhead Shark‐Inspired Microvillus‐Structured Ionic Elastomers for Wet Gas Sensing Based on Solvated Ion Transport

Advanced Functional Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 13, 2025

Abstract Water molecules are ubiquitous disruptors of conventional gas sensing materials, often leading to diminished performance in materials that reliant on electronic signal transmission. This creates the pressing need for efficient with anti‐humidity interference properties. Here, a hammerhead shark‐inspired microvillus‐structured ionic elastomer based transmission nanoconfined space is constructed by incorporating liquids into polymer matrix. The elastomers optimized microvillus structure demonstrated 1.68‐fold higher response than flat ones, short time (9 s) toward 30 ppm triethylamine (TEA), excellent selectivity and low limit detection (LOD) (104.56 ppb). Such serves as proof‐of‐concept effectively combining solvated ion transport design develop advanced systems. With such an evident (23.52%), similar (12 s), LOD (498.05 ppb), long‐term stability (at least days) achieved at relative humidity 70%. Mechanistic investigations revealed effective ions facilitated after sequential water TEA surroundings while significantly enhanced transport. Furthermore, utility system shrimp decay monitoring under wet conditions.

Language: Английский

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Block Copolymer-Assembled Nanopore Arrays Enable Ultra-Sensitive Label-Free DNA Detection

Nanoscale Horizons, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Block copolymer self-assembly enables precise thin-film materials architectures on electrodes for nanopore blockage-based electrochemical DNA detection. This scalable method achieves 30 fM sensitivity in under 20 minutes, advancing portable and accurate biosensing technologies.

Language: Английский

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