Fuel, Journal Year: 2025, Volume and Issue: 391, P. 134782 - 134782
Published: Feb. 22, 2025
Language: Английский
Angewandte Chemie International Edition, Journal Year: 2024, Volume and Issue: 63(14)
Published: Jan. 5, 2024
Abstract Mechanochemical reactions offer methodological and environmental advantages for chemical synthesis, constantly attracting attention within the scientific community. Besides unmistakable sustainability advantages, conditions under which mechanochemical occur, namely solventless conditions, sometimes facilitate isolation of otherwise labile or inaccessible products. Despite these limited knowledge exists regarding mechanisms types intermediates involved. Nevertheless, in an expanding number cases, ex situ monitoring techniques have allowed observation, characterization, reaction transformations. In this Minireview, we present a series examples reactive been detected spanning organic, organometallic, inorganic, materials chemistry. Many were stabilized by non‐covalent interactions, played pivotal role guiding We believe that uncovering understanding such instances, growing mechanochemistry community could find novel opportunities catalysis discover new while achieving simplification design.
Language: Английский
Citations
26
Progress in Materials Science, Journal Year: 2025, Volume and Issue: unknown, P. 101432 - 101432
Published: Jan. 1, 2025
Citations
3
Journal of Organometallic Chemistry, Journal Year: 2025, Volume and Issue: 1027, P. 123508 - 123508
Published: Jan. 6, 2025
Language: Английский
Citations
2
Cell Reports Physical Science, Journal Year: 2024, Volume and Issue: 5(2), P. 101831 - 101831
Published: Feb. 1, 2024
Nickel-catalyzed radical relayed dicarbofunctionalizations of olefins, utilizing carbon electrophiles as coupling partners, present a powerful strategy for the streamlined construction aliphatic structures. However, traditional solution-phase methods encounter challenges such need bulk solvents, limited long reaction times, and air-/moisture-sensitive reagents. As an alternative strategy, ball-mill-enabled metal-catalyzed cross-coupling reactions have gained attention due to their high reactivity atomic efficiency. While many are single- two-component methodologies, three-component solid-state remain relatively scarce. In this work, we report first, our knowledge, ball-milling-enabled Ni-catalyzed reductive dicarbofunctionalization alkenes. Two distinct readily available electrophiles, Csp2 Csp3 halides, simultaneously installed across variety olefins at room temperature in highly regioselective manner withing 1.5 h. By harnessing benefits ball milling reactions, anticipate further advancements sustainable efficient synthetic methodologies.
Language: Английский
Citations
8
Green Energy & Environment, Journal Year: 2024, Volume and Issue: unknown
Published: Aug. 1, 2024
Traditional chemical processes often generate substantial waste, leading to significant pollution of water, air, and soil. Developing eco-friendly methods is crucial for economic environmental sustainability. Mechano-driven chemistry, with its potential material recyclability minimal byproducts, well-aligned green chemistry principles. Despite origins over 2000 years ago nearly 200 scientific investigation, mechano-driven has not been widely implemented in practice. This likely due a lack comprehensive understanding the complex physical effects mechanical forces, which challenge reaction efficiency scalability. review summarizes historical development discusses progress across various mechanisms, including mechanochemistry, tribochemistry, piezochemistry, contact electrification (CE) chemistry. CE-induced reactions, involving ion transfer, electron radical generation, are detailed, emphasizing dominant role radicals initiated by transfer influence through electrical double layer (EDL) formation. Advancing efficient, eco-friendly, controllable technologies can reduce reliance on traditional energy sources (such as electricity heat) toxic reagents, fostering innovation synthesis, catalytic technologies, establishing new paradigm broader applications.
Language: Английский
Citations
7
ChemSusChem, Journal Year: 2024, Volume and Issue: 17(12)
Published: Feb. 14, 2024
To address the growing demand for more sustainable and greener chemistry, mechanochemical methodologies are emerging as key players. However, to date there has been little data highlighting benefits of these rising technologies with regard process scale-up activities or implementation in commercial production scale. Herein, we report first application bead-mill technology (Dyno®-mill) synthesis Acetaminophen, known under brand name Paracetamol. Using Beckmann rearrangement, optimized solvent-free methodology delivered a final product on scale several tens grams. In comparison current solvent-based process, proposed achieves higher yield while also allowing removal solvents chemical reaction, hereby reducing one extensive drivers waste generation. The approach was compared using combination green metrics EcoScale score. paracetamol scores highest all over currently used solution-based processes.
Language: Английский
Citations
6
Advanced Science, Journal Year: 2024, Volume and Issue: 11(29)
Published: June 3, 2024
Abstract A general and modular protocol is reported for olefin difunctionalization through mechanochemistry, facilitated by cooperative radical ligand transfer (RLT) electron catalysis. Utilizing mechanochemical force catalytic amounts of 2,2,6,6‐tetramethylpiperidinyloxyl (TEMPO), ferric nitrate can leverage nitryl radicals, nitrooxy‐functional group via RLT, mediate an catalysis cycle under room temperature. diverse range activated unactivated alkenes exhibited chemo‐ regioselective 1,2‐nitronitrooxylation solvent‐free or solvent‐less conditions, showcasing excellent functional tolerance. Mechanistic studies indicated a significant impact mechanochemistry highlighted the nature this nitrative process.
Language: Английский
Citations
6
Angewandte Chemie International Edition, Journal Year: 2024, Volume and Issue: 63(48)
Published: Aug. 16, 2024
Abstract The rising prospects of mechanochemically assisted syntheses hold promise for both academia and industry, yet they face challenges in understanding and, therefore, anticipating respective reaction kinetics. Particularly, dependencies based on variations milling equipment remain little understood globally overlooked. This study aims to address this issue by identifying critical parameters through kinematic models, facilitating the reproducibility mechanochemical reactions across most prominent mills laboratory settings, namely planetary mixer mills. Through a series selected experiments replicating major classes organic, organometallic, transition metal‐catalyzed, inorganic from literature, we rationalize independence kinetics when accumulated energy criterion is met. As step forward facilitate practicability our findings, provide freely accessible online tool [†] that allows calculation different Our work advances current mechanochemistry lays foundation future rational exploration rapidly evolving field.
Language: Английский
Citations
6
Catalysis Communications, Journal Year: 2024, Volume and Issue: 186, P. 106831 - 106831
Published: Jan. 1, 2024
This work describes a simple method for the preparation of 5-hydroxymethylfurfural (HMF) by dehydrating fructose in DMSO, either with use an affordable catalyst or catalyst-free manner. process can be accompanied, under harsh conditions, bromide-catalyzed Kornblum oxidation hydroxyl group solvent, resulting formation 2,5-diformylfuran (DFF). The optimized techniques presented this study serve as foundation production valuable biobased furanic platform chemicals from renewable sources any laboratory, stimulating development sustainable chemistry and research related fields worldwide.
Language: Английский
Citations
5
European Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 27(30)
Published: May 18, 2024
Abstract Mechanochemistry, as an enabling technology, harnesses mechanical force to drive chemical reactions, presenting compelling advantages in organic synthesis within the principles of green chemistry. This review explores how its unique and alignment with sustainable practices have been widely developed different scientific fields Italy. As a transformative strategy for synthesis, mechanochemistry has portrayed this valuable synthetic alternative due various advantages, such solvent reduction new reaction pathways, that use brings. Nonetheless, improvements brought about by also crucial other chemistry described Italian scientists. In whole context, researchers analysed both already optimised processes feasible paving way avenues previously hampered all limitations belong in‐solution
Language: Английский
Citations
5