Encapsulated turmeric: An innovative approach for improving absorption and effect DOI Open Access

Rushikesh Tukaram Chavan,

R. V. Salve

The Pharma Innovation, Journal Year: 2023, Volume and Issue: 12(5), P. 2294 - 2301

Published: May 1, 2023

Turmeric, a widely recognized natural supplement, has been shown to have range of health benefits due its anti-inflammatory and antioxidant properties. However, the bioavailability turmeric is limited poor solubility, rapid metabolism, low absorption in gastrointestinal tract. Encapsulation an innovative approach that can help address these issues improve efficacy supplements. This review examines current research on encapsulated potential for improving effectiveness. techniques such as liposomes, solid lipid nanoparticles, nanoemulsions enhance by protecting active compounds from degradation their body. These also found increase duration turmeric's beneficial effects.

Language: Английский

The Combined Treatment of Curcumin with Verapamil Ameliorates the Cardiovascular Pathology in a Williams–Beuren Syndrome Mouse Model DOI Open Access
Noura Abdalla, Paula Ortiz‐Romero, Isaac Rodríguez-Rovira

et al.

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(4), P. 3261 - 3261

Published: Feb. 7, 2023

Williams-Beuren syndrome (WBS) is a rare disorder caused by recurrent microdeletion with hallmarks of cardiovascular manifestations, mainly supra-valvular aortic stenosis (SVAS). Unfortunately, there currently no efficient treatment. We investigated the effect chronic oral treatment curcumin and verapamil on phenotype murine model WBS harbouring similar deletion, CD (complete deletion) mice. analysed systolic blood pressure in vivo histopathology ascending aorta left ventricular myocardium to determine effects treatments their underlying mechanism. Molecular analysis showed significantly upregulated xanthine oxidoreductase (XOR) expression This overexpression concomitant increased levels nitrated proteins as result byproduct-mediated oxidative stress damage, indicating that XOR-generated impacts pathophysiology manifestations WBS. Only combined therapy resulted significant improvement parameters via activation nuclear factor erythroid 2 (NRF2) reduction XOR protein levels. Our data suggested inhibition damage could help prevent severe injuries this disorder.

Language: Английский

Citations

2

Encapsulation of turmeric extract and rice bran oil in alginate hydrogel microcapsules DOI Open Access

Hanan Ali

Food Technology Research Journal, Journal Year: 2024, Volume and Issue: 3(1), P. 47 - 58

Published: March 1, 2024

Turmeric extract (TAE) and rice bran oil (RBO) have grown in popularity among consumers recent years due to their wide spectrum of biological activity. The main bioactive component turmeric, curcumin, has demonstrated promise as a possible anti-carcinogenic agent. Meanwhile, RBO rich γ-oryzanol other phytosterols, efficacy enhancing immune system function, thereby shielding the body against diseases. Microencapsulation ability conceal distinct taste smell shield substances from environmental elements. Alginate hydrogels possess several outstanding characteristics, including hydrophilicity, biodegradability, biocompatibility, non-toxicity, that make them suitable for enveloping food components. objective this study was obtain characterize alginate microcapsules containing turmeric aqueous evaluate effect freeze drying air on curcumin; γ-Oryzanol; total phenols contents DPPH TAE microcapsules. Chemical sensory evaluation showed Non-dried freeze-dried were significantly accepted.

Language: Английский

Citations

0

The Effect of Curcumin on Glucolipid Metabolic Disorders: A Review DOI

Lifen Mo,

Siyu Wan,

Tekla Zékány-Nagy

et al.

Food Reviews International, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 35

Published: Oct. 8, 2024

Curcumin is a natural polyphenol, with different name diferuloylmethane, found in Curcuma longa (turmeric) remarkable antioxidant, antimicrobial, anti-inflammatory, antiangiogenic, and antiplatelet aggregation properties. In recent years, several studies have verified that curcumin may benefit glucolipid metabolic disorders due to its various Glucolipid disorders, major health threats human life, series of diseases the disturbance glucose lipid which are influenced by genetic, environmental, psychiatric, dietary, other factors, including diabetes, hyperlipidemia, hypertension, obesity, dysfunction-associated fatty liver disease, atherosclerosis. Here, we discusses effects underlying mechanisms on how alleviate disorders.

Language: Английский

Citations

0

A Review on Phytopharmacological Properties of Caesalpinia crista DOI Open Access

Jaspreet Sodhi,

Birendra Shrivastava,

Hardarshan Singh Lamba

et al.

Indian Journal of Pharmaceutical Sciences, Journal Year: 2023, Volume and Issue: 85(4)

Published: Jan. 1, 2023

To explore the function of curcumin on cartilage cells, cell proliferation and apoptosis by transforming growth factor-beta/suppressor mothers against decapentaplegic/a disintegrin metalloproteinase with thrombospondin motifs-7 axis was objective study. The viability detected counting kit-8. expression factor-beta, suppressor decapentaplegic protein, a motifs-7, caspase-9, B-cell lymphoma 2, Bcl-2-associated X protein determined Western blot. cells were treated 1 mmol/l sodium nitroprusside for 24 h. Then, different concentration We found that μmol/l could recover proliferation. factor-beta show high low in treatment group. Meanwhile, pathway also detected. caspase-9 2 higher group than without However, lower. viability, proteins no changes or when inhibited. over expression, group, curcumin. Curcumin can promote via inhibit apoptosis. indian sex, free porno, kannada desi xxx hd, xnxx video, tamil sex

Language: Английский

Citations

1

Encapsulated turmeric: An innovative approach for improving absorption and effect DOI Open Access

Rushikesh Tukaram Chavan,

R. V. Salve

The Pharma Innovation, Journal Year: 2023, Volume and Issue: 12(5), P. 2294 - 2301

Published: May 1, 2023

Turmeric, a widely recognized natural supplement, has been shown to have range of health benefits due its anti-inflammatory and antioxidant properties. However, the bioavailability turmeric is limited poor solubility, rapid metabolism, low absorption in gastrointestinal tract. Encapsulation an innovative approach that can help address these issues improve efficacy supplements. This review examines current research on encapsulated potential for improving effectiveness. techniques such as liposomes, solid lipid nanoparticles, nanoemulsions enhance by protecting active compounds from degradation their body. These also found increase duration turmeric's beneficial effects.

Language: Английский

Citations

0