This
study
investigated
the
catalytic
activities
of
two
Ru
complexes
with
bifunctional
metal-ligand
cooperativity,
named
1b
(containing
a
2-hydroxypyridyl
fragment
and
protic
NHC)
2b
(only
containing
NHC),
for
C-C
bond
formation
through
borrowing
hydrogen
process.
Surprisingly,
complex
2b,
which
lacks
fragment,
exhibited
comparable
activity
to
same
catalyst
loading
in
coupling
broad
range
primary
secondary
alcohols.
The
efficiency
this
straightforward
system
was
further
demonstrated
challenging
reaction
β-alkylation
1-phenylethanol
benzyl
alcohol,
minimal
0.0001
mol%.
highest
TOF
observed
cross-coupling
alcohols
13333
h-1.
Additionally,
found
be
effective
catalysing
aliphatic
double
C-alkylation
cyclopentanol.
finding
holds
promise
development
more
catalysts
reactions
Catalysis Science & Technology,
Journal Year:
2022,
Volume and Issue:
12(12), P. 4050 - 4056
Published: Jan. 1, 2022
A
heteroditopic
Ru(
ii
)-bis-NHC
complex
in
combination
with
dppe
was
developed
as
an
effective
catalyst
system
(0.2
mol%
loading)
for
the
N
-alkylation
of
amides
and
selective
mono-/di-alkylation
4-aminobenzamide
derivatives
excellent
yields.
Chemistry - A European Journal,
Journal Year:
2024,
Volume and Issue:
30(46)
Published: June 12, 2024
The
synthesis
of
sulfoxide-functionalized
NHC
ligand
precursors
were
carried
out
by
direct
and
mild
oxidation
from
corresponding
thioether
with
high
selectivity.
Using
these
salts,
a
series
cationic
[Ru(II)(η
This
study
investigated
the
catalytic
activities
of
two
Ru
complexes
with
bifunctional
metal-ligand
cooperativity,
named
1b
(containing
a
2-hydroxypyridyl
fragment
and
protic
NHC)
2b
(only
containing
NHC),
for
C-C
bond
formation
through
borrowing
hydrogen
process.
Surprisingly,
complex
2b,
which
lacks
fragment,
exhibited
comparable
activity
to
same
catalyst
loading
in
coupling
broad
range
primary
secondary
alcohols.
The
efficiency
this
straightforward
system
was
further
demonstrated
challenging
reaction
β-alkylation
1-phenylethanol
benzyl
alcohol,
minimal
0.0001
mol%.
highest
TOF
observed
cross-coupling
alcohols
13333
h-1.
Additionally,
found
be
effective
catalysing
aliphatic
double
C-alkylation
cyclopentanol.
finding
holds
promise
development
more
catalysts
reactions
