A hybrid nanocomposite based on CuFe layered double hydroxide coated graphene oxide for photocatalytic degradation of trimethoprim

Chemosphere, Journal Year: 2023, Volume and Issue: 322, P. 138243 - 138243

Published: Feb. 23, 2023

Language: Английский

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Aliphatic C–H Functionalization Using Pyridine N-Oxides as H-Atom Abstraction Agents

ACS Catalysis, Journal Year: 2022, Volume and Issue: 12(16), P. 10499 - 10505

Published: Aug. 10, 2022

The alkylation and heteroarylation of unactivated tertiary, secondary, primary C(sp3)-H bonds was achieved by employing an acridinium photoredox catalyst along with readily available pyridine Noxides as hydrogen atom transfer (HAT) precursors under visible light. Oxygen-centered radicals, generated single-electron oxidation the Noxides, are proposed key intermediates whose reactivity can be easily modified structural adjustments. A broad range aliphatic C-H substrates electron-donating or -withdrawing groups well various olefinic radical acceptors heteroarenes were tolerated.

Language: Английский

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Phototriggered Self-Catalyzed Phosphorylation of 3,4-Dihydroquinoxalin-2(1H)-ones with Diarylphosphine Oxides in EtOH

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 19, 2024

A highly effective external photocatalyst- and additive-free method for the phosphorylation of 3,4-dihydroquinoxalin-2(1

Language: Английский

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Recent advances in the photocatalytic synthesis of aldehydes

Organic Chemistry Frontiers, Journal Year: 2023, Volume and Issue: 10(16), P. 4198 - 4210

Published: Jan. 1, 2023

This review summarizes the recently developed photocatalytic strategies for installation of formyl group into various scaffolds.

Language: Английский

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Heterogeneous visible-light promoted dehydrogenative [4 + 2] annulation of benzothioamides and alkynes under aerobic conditions

Green Chemistry, Journal Year: 2023, Volume and Issue: 25(13), P. 5206 - 5212

Published: Jan. 1, 2023

We have developed a visible-light induced dehydrogenative [4 + 2] annulation of benzothioamides and alkynes under aerobic conditions to synthesize isothiochromenes.

Language: Английский

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Visible Light‐Promoted Catalyst‐Free (VLCF) Scalable Synthesis of Novel Derivatives of Isoniazid and Maleimide

ChemistrySelect, Journal Year: 2024, Volume and Issue: 9(2)

Published: Jan. 9, 2024

Abstract We have developed a Visible Light Promoted Catalyst‐Free (VLCF) approach to synthesize novel conjugates of Isoniazid and Maleimide. This method involves the formation an electron donor‐acceptor (EDA) complex between isoniazid maleimide photochemical activity this drives transformation. successfully synthesized Isoniazid‐Maleimide derivatives (3a–d) at gram scale under visible light irradiation without additional photo catalyst chromatographic purification resulting in excellent yields recyclable green solvent. Molecular docking was employed predict silico anti‐tubercular binding modes active site enoyl‐ACP reductase, InhA. The newly compounds exhibited high affinity compared Isoniazid‐NAD adduct, indicating their potential for more effective activity. ADME analysis revealed favourable physicochemical properties, lipophilicity, water solubility, pharmacokinetics, drug‐likeness compound 3a, positioning it as promising candidate further drug discovery development.

Language: Английский

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Selective and effective oxidation of ammonium to dinitrogen in MgO/Na2SO3/K2S2O8 system

Chemosphere, Journal Year: 2023, Volume and Issue: 325, P. 138401 - 138401

Published: March 14, 2023

Language: Английский

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K₂S₂O₈-Promoted Consecutive Tandem Cyclization/Oxidative Halogenation: Access to 3-Halo-Pyrazolo[1,5-a]pyrimidines

ACS Omega, Journal Year: 2023, Volume and Issue: 8(26), P. 23851 - 23859

Published: June 22, 2023

A one-pot methodology has been developed to synthesize 3-halo-pyrazolo[1,5-a]pyrimidine derivatives through the three-component reaction of amino pyrazoles, enaminones (or chalcone), and sodium halides. The use easily accessible 1,3-biselectrophilic reagents like chalcone offers a straightforward approach for synthesis 3-halo-pyrazolo[1,5-a]pyrimidines. proceeded cyclocondensation between pyrazoles with enaminones/chalcone in presence K2S2O8 followed by oxidative halogenations NaX-K2S2O8. Mild environmentally benign conditions, wide functional group tolerance, scalability are attractive facet this protocol. combination NaX-K2S2O8 is also beneficial direct pyrazolo[1,5-a]pyrimidines water.

Language: Английский

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Recent Progress of Visible Light-Induced the Synthesis of C(3) (Hetero)arylthio Indole Compounds

Chinese Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 44(2), P. 398 - 398

Published: Jan. 1, 2024

The structure of 3-sulfenyl indoles widely exists in many drug molecules and natural product molecules.Its derivatives have extensive biological activities such as antibacterial, antiviral anti-tumor, are also important intermediates organic synthesis structural units synthesis.Therefore, indole compounds great application value the field medicine.The research its method has become one current hotspots.In this paper, progress recent years is reviewed, some reaction mechanisms discussed.

Language: Английский

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Visible-light-induced photocatalyst-free cascade cyclization of 3-(2-(ethynyl)phenyl)quinazolinones to sulfonated quinolino[2,1-b]quinazolinones

Chemical Communications, Journal Year: 2024, Volume and Issue: 60(56), P. 7228 - 7231

Published: Jan. 1, 2024

A visible-light-induced K 2 S O 8 -promoted cascade sulfonation/cyclization reaction to afford a series of sulfonated quinolino[2,1- b ]quinazolinones has been developed under mild conditions.

Language: Английский

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