Recent Advances in Palladium-Catalyzed Annulations for the Synthesis of Pyrrolidines DOI
Kai Wang,

Qian Wang,

Mengya Xu

et al.

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: unknown, P. 141010 - 141010

Published: Dec. 1, 2024

Language: Английский

Enantioselective Synthesis of Oxazocines via MQ‐Phos Enabled Palladium‐Catalyzed Asymmetric Formal [4+4]‐Cycloadditions DOI Creative Commons

Qingcheng Meng,

Yinggao Meng,

Qinglin Liu

et al.

Advanced Science, Journal Year: 2024, Volume and Issue: 11(31)

Published: June 17, 2024

Abstract Oxazocines are key structural intermediates in the synthesis of natural products and pharmaceutical molecules. However, oxazocines especially a highly enantioselective manner, is long‐standing formidable challenge due to unfavorable energetics involved cyclization. Herein, series new PNP‐Ligand P ‐chiral stereocenter first designed synthesized, called MQ‐Phos , successfully applied it Pd‐catalyzed higher‐order formal [4+4]‐cycloaddition α β ‐unsaturated imines with 2‐(hydroxymethyl)‐1‐arylallyl carbonates. The reaction features mild conditions, excellent regio‐ enantiocontrol broad substrate scope (54 examples). Various medium‐sized rings can be afforded moderate yields (up 92%) enantioselectivity 99% ee). newly developed critical for ring catalytic reactivity enantioselectivity.

Language: Английский

Citations

6
Recent Advances in Palladium-Catalyzed [4 + n] Cycloaddition of Lactones, Benzoxazinanones, Allylic Carbonates, and Vinyloxetanes DOI
Mengyan Guo, Panke Zhang, Er‐Qing Li

et al.

Topics in Current Chemistry, Journal Year: 2023, Volume and Issue: 381(6)

Published: Nov. 3, 2023

Language: Английский

Citations

9
Ring expansion of spirocyclopropanes with stabilized sulfonium ylides: highly diastereoselective synthesis of cyclobutanes DOI Creative Commons
Hisanori Nambu,

Yuta Onuki,

Kana Aso

et al.

Chemical Communications, Journal Year: 2024, Volume and Issue: 60(34), P. 4537 - 4540

Published: Jan. 1, 2024

A novel method was devised for regioselective ring expansion of spirocyclopropanes to spirocyclobutanes with stabilized sulfonium ylides, affording 1,2- trans -disubstituted 6,8-dioxaspiro[3.5]nonane-5,9-diones without the formation any isomers.

Language: Английский

Citations

3
The literature of heterocyclic chemistry, part XXII, 2022 DOI
Галина А. Газиева, Yu. B. Evdokimenkova, N. O. Soboleva

et al.

Advances in heterocyclic chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

Citations

0
Chemoselective synthesis of tunable poly-functionalized binary pyrazolyl and annulated pyrazolo/pyrido anchored on quinolinone: insecticidal and antioxidant studies DOI Creative Commons

Nedaa N. Elnaggar,

Wafaa S. Hamama,

Mohamed Abd El Salam

et al.

RSC Advances, Journal Year: 2025, Volume and Issue: 15(8), P. 6050 - 6067

Published: Jan. 1, 2025

Several fused/binary pyrazole quinolinone hybrids are synthesized via tandem reactions and their insecticidal efficacy against S. littoralis A. gossypii evaluated.

Language: Английский

Citations

0
Recent Progress in the Synthesis of Silaspiranes DOI Open Access
Hua Chen, Xuejiao Hu,

Wanshu Wang

et al.

Chemistry - A European Journal, Journal Year: 2023, Volume and Issue: 29(70)

Published: Sept. 23, 2023

Abstract Silaspiranes bearing a spiro‐silicon center are promising ring frameworks for the synthesis of novel spirocyclic molecules possessing unique properties. Development efficient methods towards these structures has therefore attracted considerable attentions synthetic chemists. This minireview highlights representative advances in field, and is categorized into four parts according to formation strategies: cyclization, annulation, expansion cycloaddition.

Language: Английский

Citations

7
Chemodivergent mechanosynthesis of cyclopentenyl and pyrrolinyl spirobarbiturates from unsaturated barbiturates and enamino esters DOI
Mingjun Li, Mingming Lu, Peng Xu

et al.

Chemical Communications, Journal Year: 2024, Volume and Issue: 60(29), P. 3958 - 3961

Published: Jan. 1, 2024

A controllable spirocyclization of unsaturated barbiturates with enamines to selectively synthesize spirobarbiturates has been developed under ball-milling conditions.

Language: Английский

Citations

2
Sc(OTf)3-Catalyzed Precise Construction of Medium-Sized [4.2.1]-Oxabridged Scaffolds DOI

Dong-Sheng Ji,

Chenxing Zhou,

Xudong Wang

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 18, 2024

In this study, the readily available and inexpensive Sc(OTf)

Language: Английский

Citations

2
Rh(II)‐Catalyzed Homocoupling/[4+1] Cycloaddition Cascade of Diazobarbiturates with Diazopyrazolones to Prepare Spirobarbiturates DOI
Kuo Wang, Yue Zhang,

Yu‐Hang Mi

et al.

Advanced Synthesis & Catalysis, Journal Year: 2024, Volume and Issue: 366(11), P. 2596 - 2601

Published: April 9, 2024

Abstract Under the catalysis of Rh 2 (OAc) 4 (10 mol%) and (±)‐Me‐Pybox (20 in 1,2‐DCE at 80 °C, homocoupling/[4+1] cycloaddition cascade diazobarbiturates with diazopyrazolones proceeded readily provided spirobarbiturates 32–88% chemical yields. The structure obtained was identified by X‐ray diffraction analysis.

Language: Английский

Citations

1
Synthesis and transformations of 2,4-dioxa- and 2,4-diazaspiro[5.5]undecanones equipped with a diterpenoid substituent DOI

Maxim E. Mironov,

Elvira E. Shults

Russian Chemical Bulletin, Journal Year: 2023, Volume and Issue: 72(10), P. 2453 - 2465

Published: Oct. 1, 2023

Language: Английский

Citations

3