Novel transition metal-free synthetic protocols toward the construction of 2,3-dihydrobenzofurans: a recent update DOI Creative Commons
Aqsa Mushtaq, Muhammad Irfan, Atta ul Haq

et al.

Frontiers in Chemistry, Journal Year: 2024, Volume and Issue: 12

Published: Dec. 13, 2024

2,3-Dihydrobenzofurans are noteworthy scaffolds in organic and medicinal chemistry, constituting the structural framework of many varied medicinally active compounds. Moreover, a diverse variety biologically potent natural products also contain this heterocyclic nucleus. Reflecting on wide biological substantiality dihydrobenzofurans, several innovative facile synthetic developments evolving to achieve these heterocycles. This review summarizes transition-metal-free, efficient, novel pathways toward constructing dihydrobenzofuran nucleus established after 2020.

Language: Английский

Development of novel transition metal-catalyzed synthetic approaches for the synthesis of a dihydrobenzofuran nucleus: a review DOI Creative Commons

Rabia Ashraf,

Ameer Fawad Zahoor, Kulsoom Ghulam Ali

et al.

RSC Advances, Journal Year: 2024, Volume and Issue: 14(21), P. 14539 - 14581

Published: Jan. 1, 2024

The synthesis of dihydrobenzofuran scaffolds bears pivotal significance in the field medicinal chemistry and organic synthesis. These heterocyclic hold immense prospects owing to their significant pharmaceutical applications as they are extensively employed essential precursors for constructing complex frameworks. Their versatility importance make them an interesting subject study researchers scientific community. While exploring synthesis, have unveiled various novel efficient pathways assembling core. In wake extensive data being continuously reported each year, we outlined recent updates (post 2020) on methodological accomplishments employing catalytic role several transition metals forge functionalities.

Language: Английский

Citations

6

Electron shuttles mediated bioelectrochemical degradation of volatile chlorinated hydrocarbons: A review DOI
Kai Zhu,

Fenqi Wu,

Jun Dong

et al.

Journal of Water Process Engineering, Journal Year: 2024, Volume and Issue: 58, P. 104744 - 104744

Published: Jan. 13, 2024

Language: Английский

Citations

6

Synthesis and Analysis of Ketoprofen 1,4-Sorbitan Ester DOI Creative Commons
Pooreum Lim, Jae Ho Shim

Molbank, Journal Year: 2025, Volume and Issue: 2025(1), P. M1954 - M1954

Published: Jan. 21, 2025

This study presents the synthesis and comprehensive characterization of ketoprofen 1,4-sorbitan ester, a novel compound with potential applications in drug delivery. The was synthesized through two-step process involving acid-catalyzed dehydration D-Glucose to form 1,4-sorbitan, followed by esterification ketoprofen. structures ester reference compound, methyl were rigorously analyzed using combination advanced analytical techniques. High-resolution accurate mass liquid chromatography–mass spectrometry used determine precise molecular elemental composition compounds. 1H 13C nuclear magnetic resonance spectroscopy provided detailed information on structure atomic connectivity identify specific functional groups confirm formation bonds.

Language: Английский

Citations

0

Novel transition metal-free synthetic protocols toward the construction of 2,3-dihydrobenzofurans: a recent update DOI Creative Commons
Aqsa Mushtaq, Muhammad Irfan, Atta ul Haq

et al.

Frontiers in Chemistry, Journal Year: 2024, Volume and Issue: 12

Published: Dec. 13, 2024

2,3-Dihydrobenzofurans are noteworthy scaffolds in organic and medicinal chemistry, constituting the structural framework of many varied medicinally active compounds. Moreover, a diverse variety biologically potent natural products also contain this heterocyclic nucleus. Reflecting on wide biological substantiality dihydrobenzofurans, several innovative facile synthetic developments evolving to achieve these heterocycles. This review summarizes transition-metal-free, efficient, novel pathways toward constructing dihydrobenzofuran nucleus established after 2020.

Language: Английский

Citations

0